Design, synthesis, and biological activity of diaryl ether inhibitors of Toxoplasma gondii enoyl reductase.
about
The benzimidazole based drugs show good activity against T. gondii but poor activity against its proposed enoyl reductase enzyme targetModification of triclosan scaffold in search of improved inhibitors for enoyl-acyl carrier protein (ACP) reductase in Toxoplasma gondii.Drugs in development for toxoplasmosis: advances, challenges, and current status.Discrimination of potent inhibitors of Toxoplasma gondii enoyl-acyl carrier protein reductase by a thermal shift assay.Triazole-based compound as a candidate to develop novel medicines to treat toxoplasmosis.1,4-Disubstituted thiosemicarbazide derivatives are potent inhibitors of Toxoplasma gondii proliferation.Development of a triclosan scaffold which allows for adaptations on both the A- and B-ring for transport peptides.
P2860
Q27681222-6F01E291-22A7-499A-9DCA-0366C8ED9E91Q37128281-991242C7-4325-4F92-8EE9-4EB139FCC998Q37613765-9A2B64BF-C197-4A53-8400-345E8368AEB6Q37635732-93890E36-0CBD-4607-A345-9B886AC57AA2Q38950127-CE8CA716-3F64-41C8-8727-F4901B78176FQ38976714-3004F1E4-F020-4294-A7A0-86FCD26EE66BQ39420787-F38426FD-3D29-4222-AA67-68A03F8C509F
P2860
Design, synthesis, and biological activity of diaryl ether inhibitors of Toxoplasma gondii enoyl reductase.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
@zh
2013年學術文章
@zh-hant
name
Design, synthesis, and biologi ...... plasma gondii enoyl reductase.
@en
Design, synthesis, and biologi ...... plasma gondii enoyl reductase.
@en-gb
Design, synthesis, and biologi ...... plasma gondii enoyl reductase.
@nl
type
label
Design, synthesis, and biologi ...... plasma gondii enoyl reductase.
@en
Design, synthesis, and biologi ...... plasma gondii enoyl reductase.
@en-gb
Design, synthesis, and biologi ...... plasma gondii enoyl reductase.
@nl
prefLabel
Design, synthesis, and biologi ...... plasma gondii enoyl reductase.
@en
Design, synthesis, and biologi ...... plasma gondii enoyl reductase.
@en-gb
Design, synthesis, and biologi ...... plasma gondii enoyl reductase.
@nl
P2093
P2860
P50
P1476
Design, synthesis, and biologi ...... plasma gondii enoyl reductase.
@en
P2093
Alina Fomovska
Bo Shiun Lai
David W Rice
Ernest J Mui
Gustavo A Afanador
Jennifer M Auschwitz
Mark R Hickman
Patty J Lee
Rima McLeod
Susan E Leed
P2860
P304
P356
10.1016/J.BMCL.2013.02.019
P407
P577
2013-02-13T00:00:00Z