Selective targeting of the BRG/PB1 bromodomains impairs embryonic and trophoblast stem cell maintenance.
about
Discovery and Optimization of a Selective Ligand for the Switch/Sucrose Nonfermenting-Related Bromodomains of Polybromo Protein-1 by the Use of Virtual Screening and Hydration AnalysisStructure-Based Design of an in Vivo Active Selective BRD9 InhibitorTargeting the Bromome: are we there yet?Chemical probes targeting epigenetic proteins: Applications beyond oncology.Targeting the chromatin remodeling enzyme BRG1 increases the efficacy of chemotherapy drugs in breast cancer cellsPromiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia.Mammalian SWI/SNF Enzymes and the Epigenetics of Tumor Cell Metabolic Reprogramming.Selective targeting of Bromodomains of the Bromodomain-PHD Fingers family impairs osteoclast differentiation.Progress in the Development of non-BET Bromodomain Chemical Probes.Epigenomic regulation of oncogenesis by chromatin remodeling.Selective targeting of epigenetic reader domains.Bromodomain inhibitors and cancer therapy: From structures to applications.Mammalian SWI/SNF complexes in cancer: emerging therapeutic opportunities.Identification of a Chemical Probe for Family VIII Bromodomains through Optimization of a Fragment HitDNA binding drives the association of BRG1/hBRM bromodomains with nucleosomes.Tumor suppression via inhibition of SWI/SNF complex-dependent NF-κB activationIdentification and Development of 2,3-Dihydropyrrolo[1,2-a]quinazolin-5(1H)-one Inhibitors Targeting Bromodomains within the Switch/Sucrose Nonfermenting Complex.Histone propionylation is a mark of active chromatin.Chemical probes and inhibitors of bromodomains outside the BET family.The BRG1 ATPase of human SWI/SNF chromatin remodeling enzymes as a driver of cancer.Large-scale analysis of water stability in bromodomain binding pockets with grand canonical Monte CarloSCF-mediated degradation of Brg1 suppresses gastric cancer metastasis
P2860
Q27728041-407CB845-EA92-4080-8EF5-82CF494264EFQ28829832-C0AF1EA2-60D8-49BC-B76F-4D7DD93F147BQ30489777-CA9B5753-7714-44FA-96BB-343C3B6BACC7Q33751386-C679C705-2F89-40E6-97E5-A13F1040D929Q37317194-8E14A233-857D-45DF-84C4-4C2303AD917EQ37334404-5F167F77-3DD5-4159-A9A1-522F89DAF811Q37736010-602FA487-B5FE-49A9-AAC1-E1C9BC6E8586Q38604141-5B5C3A37-B31B-4152-8E9B-E6C4C7402AD6Q38691377-0BE500F5-AEDB-41DD-93B9-9E4B20E42CE1Q38709544-B94CFB61-0AB2-4DB0-A0A7-AFA48FD97463Q38748150-050AA13C-7ADE-4E72-9BB8-699C325387FCQ39027056-CF244C8B-597E-4E19-8785-EA4BBDE023A2Q39229171-6B7DA911-0204-45B0-9573-174495B9613FQ39821089-4C2620F5-BAC1-477D-AA04-2554452BB0EAQ41077356-3659CB7A-5AB6-4E63-8BD6-FC55A35C6FB6Q41718087-C826C31F-26EC-40A1-919B-7943CA2C8E7DQ42540410-EBA94126-C754-4707-83F2-38BFDEEE5757Q43065475-E0FF9991-BFFF-4F9F-BE84-587091DC6BBBQ47128083-A1127537-CAF0-4993-BE1A-8597CA7C221BQ50640303-1BF5B028-0EC2-4140-8DDE-FF6B8774CDE3Q56815991-B9DF35B9-F737-4A85-BEB2-0A9CFA674B5AQ57753119-41D0CB0F-78D4-4866-9ECE-16783554F8DC
P2860
Selective targeting of the BRG/PB1 bromodomains impairs embryonic and trophoblast stem cell maintenance.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Selective targeting of the BRG ...... hoblast stem cell maintenance.
@en
type
label
Selective targeting of the BRG ...... hoblast stem cell maintenance.
@en
prefLabel
Selective targeting of the BRG ...... hoblast stem cell maintenance.
@en
P2093
P2860
P50
P356
P1433
P1476
Selective targeting of the BRG ...... phoblast stem cell maintenance
@en
P2093
Brian S Gerstenberger
Cynthia Tallant
Dafydd R Owen
Dominica Willmann
Josefina Castex
Mark E Bunnage
Martin Philpott
Octovia Monteiro
Panagis Filippakopoulos
Roland Schüle
P2860
P304
P356
10.1126/SCIADV.1500723
P50
P577
2015-11-13T00:00:00Z