Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k. - Test2 - elhamkhani - TriplyDB

Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k.

Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k.

http://www.wikidata.org/entity/Q41106936

about

Differential regulation of the phosphatidylinositol 3-kinase/Akt and p70 S6 kinase pathways by the alpha(1A)-adrenergic receptor in rat-1 fibroblasts The regulation of protein synthesis and translation factors by CD3 and CD28 in human primary T lymphocytes.mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E Ribosomal protein S6 is a selective mediator of TRAIL-apoptotic signaling Classification of gas5 as a multi-small-nucleolar-RNA (snoRNA) host gene and a member of the 5'-terminal oligopyrimidine gene family reveals common features of snoRNA host genes.Elucidating TOR signaling and rapamycin action: lessons from Saccharomyces cerevisiae.Protein kinase C phosphorylates ribosomal protein S6 kinase betaII and regulates its subcellular localization.8p12 stem cell myeloproliferative disorder: the FOP-fibroblast growth factor receptor 1 fusion protein of the t(6;8) translocation induces cell survival mediated by mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt/mTOR pathways Phosphorylation of the cap-binding protein eukaryotic translation initiation factor 4E by protein kinase Mnk1 in vivo PRMT3 is a ribosomal protein methyltransferase that affects the cellular levels of ribosomal subunits mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells mTOR/p70S6K signaling distinguishes routine, maintenance-level autophagy from autophagic cell death during influenza A infection Functional interaction between RAFT1/FRAP/mTOR and protein kinase cdelta in the regulation of cap-dependent initiation of translation S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway Time-restricted role for dendritic activation of the mTOR-p70S6K pathway in the induction of late-phase long-term potentiation in the CA1 Dual requirement for a newly identified phosphorylation site in p70s6k Specification of neuronal polarity regulated by local translation of CRMP2 and Tau via the mTOR-p70S6K pathway RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1 Overcoming cisplatin resistance by mTOR inhibitor in lung cancer.Human Cytomegalovirus Strategies to Maintain and Promote mRNA Translation The role and regulation of mTOR in T-lymphocyte function Role of AKT/mTORC1 pathway in pancreatic β-cell proliferation Flavivirus Activates Phosphatidylinositol 3-Kinase Signaling To Block Caspase-Dependent Apoptotic Cell Death at the Early Stage of Virus Infection Diverse diseases from a ubiquitous process: the ribosomopathy paradox Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic Tor proteins and protein phosphatase 2A reciprocally regulate Tap42 in controlling cell growth in yeast.Eap1p, a novel eukaryotic translation initiation factor 4E-associated protein in Saccharomyces cerevisiae.Regulation of ribosome biogenesis by the rapamycin-sensitive TOR-signaling pathway in Saccharomyces cerevisiae.mTOR, a new potential target for chronic pain and opioid-induced tolerance and hyperalgesia Regulation of ribosomal S6 kinase 2 by effectors of the phosphoinositide 3-kinase pathway Regulation of the rapamycin and FKBP-target 1/mammalian target of rapamycin and cap-dependent initiation of translation by the c-Abl protein-tyrosine kinase Characterization of S6K2, a novel kinase homologous to S6K1 Rapamycin-sensitive signalling in long-term consolidation of auditory cortex-dependent memory Distinct regulatory mechanism for p70 S6 kinase beta from that for p70 S6 kinase alpha ARD1 stabilization of TSC2 suppresses tumorigenesis through the mTOR signaling pathway Rapalogs and mTOR inhibitors as anti-aging therapeutics TCR-dependent translational control of GATA-3 enhances Th2 differentiation Interleukins 2 and 15 regulate Ets1 expression via ERK1/2 and MNK1 in human natural killer cells p70(s6k) integrates phosphatidylinositol 3-kinase and rapamycin-regulated signals for E2F regulation in T lymphocytes A maize insulin-like growth factor signals to a transduction pathway that regulates protein synthesis in maize

P2860

Q22253167-E923407E-1F17-4302-97F3-8EE71C45A45E Q24298073-9310290F-C19D-471E-8F76-4CF823FD6110 Q24301780-D484858D-054D-4000-85DA-85F7B1AAA506 Q24314084-FCA3C94D-7AEB-48ED-AE24-AAB564532AFF Q24522827-A774067E-50A5-4E3A-A548-2AC463305958 Q24537557-663B0B23-51E0-4111-AA23-B9C0AD302553 Q24540893-DB9E8E14-FE6C-4DB7-A765-BB5AEB7A4C65 Q24548250-A343D553-B4B4-47C2-8D52-9097FA73CB19 Q24554527-101AB6BD-0728-462E-851A-FC4910534850 Q24563414-2392EF70-62ED-4E75-86AE-FDAD02E259CE Q24564276-95D282E7-38BE-4CFF-929F-80C97D56D757 Q24567565-CFEAE069-F54E-46D8-A98F-5438179545C5 Q24600427-746A805E-236D-4449-9476-1B603283DD85 Q24603083-13DB0885-FB10-4F9C-B9B1-D3CD7B627856 Q24630599-DC1EDEA1-3C37-4754-9104-8DD1AE3E8320 Q24644595-742E0486-5A3D-4FBE-A900-2252E8EC0399 Q24648040-6F7425A7-1D85-4CBC-BACF-512163025608 Q24682697-D729FABC-DA02-405E-BC1C-5555A5566D48 Q24815638-74AC726A-BF12-4416-B4E0-F60BB1510D4E Q26752742-972FB753-86C2-40C9-8A9B-75F565816AE1 Q26830161-A698A430-CEEF-451A-820A-D2E5D807B820 Q27026943-6C11D4B8-E560-4703-B1A0-B0D2311A9B6B Q27469840-1BCEF678-A38F-44E3-BC6B-0A40B4B6FD67 Q27694538-320B24A7-9393-4ADB-99E4-82C675501BAE Q27824826-56C164F6-85C7-482B-8FB5-94C2B712D0A5 Q27930579-2927C662-A2D6-4E22-AC3B-CCF9B71440DE Q27932207-5224CB40-F016-4B03-B60F-F3F7CA7CFEDD Q27937080-A1D46EEF-83F4-44DC-A93B-335324C8CF41 Q28081540-DF4893CB-EF74-4FA0-81C1-556CFF4499DA Q28139573-7D10927A-FDB5-48D3-AB2E-7E80FD3539C8 Q28141152-82E06AB7-DB8C-46E5-87D4-3BDB16C40858 Q28144592-DD259CC6-953C-4ACD-BE6C-FA647DFAACB1 Q28202260-2D1F5202-7866-4562-BC76-BB7AFFFF01DE Q28208587-1775694C-CC5A-4347-A113-10CAB8D19E74 Q28272830-EC9A5E05-E4A3-45F1-8C11-02FAEBF469ED Q28286510-7493F7B3-B97A-4BF7-94C0-7CD9D5EDCAB4 Q28290084-DDB2267F-8079-41E6-92BC-B09975B8C46A Q28295106-39B83E3C-6C3B-4A8B-AFBF-228D535219B9 Q28343389-E59E3927-BF61-4B64-8603-C2BD6504F868 Q28345209-D7B5067D-E3D4-47D7-BA2E-A410FB8AB16B

P2860

Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k.

http://www.wikidata.org/entity/Q41106936

description

1997 nî lūn-bûn

@nan

1997年の論文

@ja

1997年論文

@yue

1997年論文

@zh-hant

1997年論文

@zh-hk

1997年論文

@zh-mo

1997年論文

@zh-tw

1997年论文

@wuu

1997年论文

@zh

1997年论文

@zh-cn

name

Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k.

@en

type

label

Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k.

@en

prefLabel

Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k.

@en

P1433

Q41106936-0F824842-EE80-4597-AFA0-1F3504A0E31D

P1476

Q41106936-C0429074-A3F9-448F-AEB7-36B582CAE751

P2093

Q41106936-01A01B8D-FF57-42E0-B9BE-0223255D2741

Q41106936-3AA32F6A-F767-4CC9-BDDD-54775124463B

Q41106936-6C5A8DB4-1272-41FA-AB7C-46185098CA1A

Q41106936-BB6B0F20-8632-45AC-B8B7-99EF18B8B34B

Q41106936-BF4FA70E-EB94-4220-9163-DC2C59F666CF

P2860

Q41106936-020B9C13-BC9C-4B84-B91E-1BD25B6CD82F

Q41106936-02A9124A-A347-4EED-99DA-48539CC0809C

Q41106936-0429F525-3C10-4D2D-ACF5-D846F04691E3

Q41106936-0B20F200-8936-4F86-8DD4-358BDEB9E2FB

Q41106936-0C5716DC-0544-4553-9398-DA84F54012F4

Q41106936-18441D39-C975-4D63-A1E0-AA1FE4221694

Q41106936-19DB17C4-E05A-438B-A5C7-9D3FC31A8A2E

Q41106936-2234406A-BC46-403C-98B0-3EAD87921D68

Q41106936-2AF2951F-FE49-4135-90DC-B0C29FAEA670

Q41106936-2C252986-477D-4D7F-9CFC-88AF26D8B4E1

P304

Q41106936-158EB84D-089A-44D5-944C-EA8D0E9C3A86

P31

Q41106936-B87E0F2F-53E9-4C1D-9A3E-3ED08F57C5F2

P356

Q41106936-B22B9F82-B0B0-401A-BBDC-0ECF92B8465C

P407

Q41106936-543C7103-C05A-4A28-B619-979A9C7D26EF

P433

Q41106936-CB6B863F-D995-4CE1-8DE1-C0490356B875

P478

Q41106936-EBBDEBB3-341E-46ED-9462-F7E0B0666348

P50

Q41106936-80B764DD-73CF-4100-8ACD-BF05E9527C44

P577

Q41106936-EFE67A70-C01F-477F-B120-88F407CA6B33

P5875

Q41106936-367E22F7-792A-4784-82BE-6BB9B9B4C30E

P698

Q41106936-1043CECF-F067-48F7-8F3A-5B8758E3F3BB

P932

Q41106936-E60273E3-C1D2-4FCF-A77A-BE0EBCC0F420

P356

P1433

The EMBO Journal

P1476

Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k

@en

P2093

Dennis PB

http://www.w3.org/2001/XMLSchema#string

Fumagalli S

http://www.w3.org/2001/XMLSchema#string

Jefferies HB

http://www.w3.org/2001/XMLSchema#string

Reinhard C

http://www.w3.org/2001/XMLSchema#string

Thomas G

http://www.w3.org/2001/XMLSchema#string

P2860

La autoantigen alleviates translational repression by the 5' leader sequence of the human immunodeficiency virus type 1 mRNA

Genomic structure and amino acid sequence domains of the human La autoantigen

Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases

A mammalian protein targeted by G1-arresting rapamycin-receptor complex

RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs

Eukaryotic translation initiation factor 4E regulates expression of cyclin D1 at transcriptional and post-transcriptional levels

Isolation of a protein target of the FKBP12-rapamycin complex in mammalian cells

Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation

Control of PHAS-I by insulin in 3T3-L1 adipocytes. Synthesis, degradation, and phosphorylation by a rapamycin-sensitive and mitogen-activated protein kinase-independent pathway

Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

P304

3693-3704

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1093/EMBOJ/16.12.3693

http://www.w3.org/2001/XMLSchema#string

P407

P433

12

http://www.w3.org/2001/XMLSchema#string

P478

16

http://www.w3.org/2001/XMLSchema#string

P50

P577

1997-06-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

14000377

http://www.w3.org/2001/XMLSchema#string

P698

9218810

http://www.w3.org/2001/XMLSchema#string

P932

1169993

http://www.w3.org/2001/XMLSchema#string