Standardization of the physicochemical parameters to assess in vitro the beta-hematin inhibitory activity of antimalarial drugs.
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Artemisinin Antimalarials Do Not Inhibit Hemozoin FormationThe relationship of physico-chemical properties and structure to the differential antiplasmodial activity of the cinchona alkaloidsA novel way to grow hemozoin-like crystals in vitro and its use to screen for hemozoin inhibiting antimalarial compoundsMalaria pigment crystals as magnetic micro-rotors: key for high-sensitivity diagnosis.Lipophilic mediated assays for beta-hematin inhibitors.A chemotype that inhibits three unrelated pathogenic targets: the botulinum neurotoxin serotype A light chain, P. falciparum malaria, and the Ebola filovirus.Identification and SAR Evaluation of Hemozoin-Inhibiting Benzamides Active against Plasmodium falciparum.Cytostatic versus cytocidal profiling of quinoline drug combinations via modified fixed-ratio isobologram analysis.New approaches in antimalarial drug discovery and development: a review.Characterization and optimization of the haemozoin-like crystal (HLC) assay to determine Hz inhibiting effects of anti-malarial compounds.The mechanism of antimalarial action of the ruthenium(II)-chloroquine complex [RuCl(2)(CQ)] (2).A novel live-dead staining methodology to study malaria parasite viability.Synthesis and biological evaluation of acridine derivatives as antimalarial agents.Use of the NP-40 detergent-mediated assay in discovery of inhibitors of beta-hematin crystallization.Chloroquine-containing organoruthenium complexes are fast-acting multistage antimalarial agents.Platinum(ii)-chloroquine complexes are antimalarial agents against blood and liver stages by impairing mitochondrial function.Anti-plasmodial and Chloroquine Resistance Suppressive Effects of EmbelinCytostatic versus cytocidal activities of chloroquine analogues and inhibition of hemozoin crystal growth.Novel antimalarial aminoquinolines: heme binding and effects on normal or Plasmodium falciparum-parasitized human erythrocytes.The antimalarial activity of Ru-chloroquine complexes against resistant Plasmodium falciparum is related to lipophilicity, basicity, and heme aggregation inhibition ability near water/n-octanol interfaces.Trioxaquines and heme-artemisinin adducts inhibit the in vitro formation of hemozoin better than chloroquine.Development in Assay Methods for in Vitro Antimalarial Drug Efficacy Testing: A Systematic Review.Antimalarial mannoxanes: hybrid antimalarial drugs with outstanding oral activity profiles and a potential dual mechanism of action.
P2860
Q22061803-880735D9-6DBC-4E12-B9B3-40901A0E38B3Q24801973-9CCF8BA0-7D88-49C3-9396-CBF5054F13EEQ28729074-75733809-6C57-447A-AE22-34D4153AD038Q30537450-CC4D5547-A29A-442C-8BBA-9652BA3C1878Q33983849-9CA23798-CC6B-4FEA-BCEA-DE170B84FFD3Q34665879-6A15549C-69F0-493B-B867-0A7699CF5810Q37095658-75E78F80-FC2E-4B92-9A3B-79AD0D4B8FE6Q37418342-1B665262-B0A3-408E-B70F-75AE8C8D96B8Q38059380-D269E094-AC59-4DED-824C-6B2399755066Q38386039-BFBC4EB7-09A0-46CE-9CCD-26407EFFD56CQ38791312-4A5AC243-811E-41D9-A2D5-93B50A255AD0Q39341007-DA22F0BC-A422-4DC1-8396-1DFB7BB3DF12Q39396932-DC6F99A8-FF2E-48B8-83F8-480CA075BC6CQ39553293-F5ABEE51-1EB4-4C92-8A76-E79461CFA487Q40605862-2EACC829-1EF6-449A-8D2E-C3BD8DC1017AQ41911875-CC2CEE53-BA4D-43ED-981C-B804E2AAF660Q41912792-24849E18-823A-4B64-9032-AD863176710BQ41927912-F7BDB667-33B9-4488-A2CC-A5C3522AA846Q41937826-D0DF954B-FFD1-4602-8C00-138DA74BA1F7Q41938737-10F534B0-5B82-4842-92CF-8E54630483F4Q41942403-DE8FF3D7-3B6B-4C65-8B35-D4A13903F527Q45770576-2143D66B-472D-40FE-92F3-E18723A08015Q47983103-450289D7-4BBB-49F3-8917-3C663B55AD3A
P2860
Standardization of the physicochemical parameters to assess in vitro the beta-hematin inhibitory activity of antimalarial drugs.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Standardization of the physico ...... ctivity of antimalarial drugs.
@en
type
label
Standardization of the physico ...... ctivity of antimalarial drugs.
@en
prefLabel
Standardization of the physico ...... ctivity of antimalarial drugs.
@en
P2093
P356
P1476
Standardization of the physico ...... activity of antimalarial drugs
@en
P2093
P304
P356
10.1006/EXPR.2000.4583
P577
2000-12-01T00:00:00Z