Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation.
about
Molecular recognition of ternary complexes: a new dimension in the structure-guided design of chemical degraders.Thioamide substitution to probe the hydroxyproline recognition of VHL ligands.Chromatin-Bound Cullin-Ring Ligases: Regulatory Roles in DNA Replication and Potential Targeting for Cancer Therapy.Small Molecule Modulators of RING-Type E3 Ligases: MDM and Cullin Families as Targets.Surface Probing by Fragment-Based Screening and Computational Methods Identifies Ligandable Pockets on the von Hippel-Lindau (VHL) E3 Ubiquitin LigaseSmall-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs
P2860
Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation.
description
2017 nî lūn-bûn
@nan
2017年の論文
@ja
2017年論文
@yue
2017年論文
@zh-hant
2017年論文
@zh-hk
2017年論文
@zh-mo
2017年論文
@zh-tw
2017年论文
@wuu
2017年论文
@zh
2017年论文
@zh-cn
name
Homo-PROTACs: bivalent small-m ...... se to induce self-degradation.
@en
Homo-PROTACs: bivalent small-m ...... se to induce self-degradation.
@nl
type
label
Homo-PROTACs: bivalent small-m ...... se to induce self-degradation.
@en
Homo-PROTACs: bivalent small-m ...... se to induce self-degradation.
@nl
prefLabel
Homo-PROTACs: bivalent small-m ...... se to induce self-degradation.
@en
Homo-PROTACs: bivalent small-m ...... se to induce self-degradation.
@nl
P2093
P2860
P50
P1476
Homo-PROTACs: bivalent small-m ...... ase to induce self-degradation
@en
P2093
Douglas J Lamont
Scott J Hughes
Wenzhang Chen
P2860
P2888
P356
10.1038/S41467-017-00954-1
P407
P577
2017-10-10T00:00:00Z