about
CRL4B catalyzes H2AK119 monoubiquitination and coordinates with PRC2 to promote tumorigenesisIdentification and functional analysis of a SLC33A1: c.339T>G (p.Ser113Arg) variant in the original SPG42 familyEmbryonic stem cells and somatic cells differ in mutation frequency and typeA missense mutation in SLC33A1, which encodes the acetyl-CoA transporter, causes autosomal-dominant spastic paraplegia (SPG42)Modulation of DNA end joining by nuclear proteinsMutation in CUL4B, which encodes a member of cullin-RING ubiquitin ligase complex, causes X-linked mental retardationMlh1 mediates tissue-specific regulation of mitotic recombinationArtesunate sensitizes ovarian cancer cells to cisplatin by downregulating RAD51.Resveratrol sequentially induces replication and oxidative stresses to drive p53-CXCR2 mediated cellular senescence in cancer cells.Replication stress induces micronuclei comprising of aggregated DNA double-strand breaksBerberine radiosensitizes human esophageal cancer cells by downregulating homologous recombination repair protein RAD51Accelerated hepatocellular carcinoma development in CUL4B transgenic miceExome sequencing reveals a heterozygous DLX5 mutation in a Chinese family with autosomal-dominant split-hand/foot malformation.MiR-182 overexpression in tumourigenesis of high-grade serous ovarian carcinoma.Lack of Cul4b, an E3 ubiquitin ligase component, leads to embryonic lethality and abnormal placental development.Oxidative stress preferentially induces a subtype of micronuclei and mediates the genomic instability caused by p53 dysfunction.STC2 overexpression mediated by HMGA2 is a biomarker for aggressiveness of high-grade serous ovarian cancer.Chromosome instability contributes to loss of heterozygosity in mice lacking p53Mitotic recombination produces the majority of recessive fibroblast variants in heterozygous mice.HMGA2 overexpression-induced ovarian surface epithelial transformation is mediated through regulation of EMT genesA human cell-based reporter detects microhomology-mediated end joiningSerum withdrawal up-regulates human SIRT1 gene expression in a p53-dependent manner.Isoliensinine induces apoptosis in triple-negative human breast cancer cells through ROS generation and p38 MAPK/JNK activation.Prdx1 deficiency in mice promotes tissue specific loss of heterozygosity mediated by deficiency in DNA repair and increased oxidative stress.X-rays induce distinct patterns of somatic mutation in fetal versus adult hematopoietic cells.Specific deletion of TRAF3 in B lymphocytes leads to B-lymphoma development in mice.CCR2-dependent recruitment of macrophages by tumor-educated mesenchymal stromal cells promotes tumor development and is mimicked by TNFαCUL4B promotes replication licensing by up-regulating the CDK2-CDC6 cascade.Human DNA ligases I and III, but not ligase IV, are required for microhomology-mediated end joining of DNA double-strand breaks.Role of the mismatch repair gene, Msh6, in suppressing genome instability and radiation-induced mutations.GSH-dependent antioxidant defense contributes to the acclimation of colon cancer cells to acidic microenvironmentMutagenesis in vivo in T cells of p21-deficient mice.Characterization of nuclear localization signal in the N terminus of CUL4B and its essential role in cyclin E degradation and cell cycle progression.Lack of interferon-γ receptor results in a microenvironment favorable for intestinal tumorigenesis.Light-sheet-based 2D light scattering cytometry for label-free characterization of senescent cells.miR-106a represses the Rb tumor suppressor p130 to regulate cellular proliferation and differentiation in high-grade serous ovarian carcinoma.S113R mutation in SLC33A1 leads to neurodegeneration and augmented BMP signaling in a mouse model.An osteopontin-integrin interaction plays a critical role in directing adipogenesis and osteogenesis by mesenchymal stem cells.Ionizing radiation is a potent inducer of mitotic recombination in mouse embryonic stem cells.Neferine induces autophagy of human ovarian cancer cells via p38 MAPK/ JNK activation.
P50
Q24306088-A0268F13-E263-471C-9DCB-2EBCF569A54BQ24306772-7E3FF721-0F24-468C-8387-3F42E514662AQ24531480-8498ED57-C963-42B5-977B-AD71C3F19A43Q24643486-3D0BF470-84F1-4D34-BE6F-B3D3E5D685E7Q28261218-A8225204-F630-4D03-B4D3-960EEE318516Q28286574-DF7A153D-F9F7-4E7C-93F4-5D1908C45EC0Q28586588-4B18184A-E67D-4A80-96E6-10ABB334B46CQ33564205-D0FB1DFD-0B31-4B32-B500-9C2D22C5D470Q33670862-51A3365A-D128-43E8-B62C-B597FFCDEE7FQ33883336-E0E312BB-D2E3-41A3-B56D-4CFAEA38DB8BQ33999614-5596D2CE-3215-4BEE-ADA9-76B2491678ACQ34043935-88A07457-BB1D-46BF-A0E1-481AE72C48B8Q34055794-EF3F711A-BD87-4742-8FAE-86EFC40AEF06Q34253391-2C5266E0-582C-4334-9CB6-976E79D90962Q34273850-F0BAF5A5-453E-44F8-8989-F5CE6651953CQ34293764-D484FDE5-F09C-4EFC-A3E9-3260DBB2664FQ34484508-28524D80-1752-4B73-9C3D-B17D2353840EQ35159652-EAC286EC-FC97-4DD1-8F2C-AD156EFEBF72Q35600328-2F830793-507C-447A-A3D4-9512F602204DQ35615694-42A739B2-9881-4613-AA9E-8A0DD3E630D2Q35713289-5C27E132-9D53-498E-A91D-D0932BD47189Q35832028-DCF846CB-A7AC-45FA-AB7C-ECC7A712033DQ35898217-493F70F8-FE88-42C2-A404-22ECE0782430Q36074530-B103FAD4-EBB5-4EB8-BDB2-F73E1CD59516Q36116571-FE4C3872-D3BF-4E4E-92B0-4164E190D05AQ36208548-2814C625-46DF-45E9-8972-929882463466Q36456715-6C1400CE-A942-46D1-B0F5-B3B16A43CCFBQ36695607-25C0B031-FB85-41B1-8BE5-0ABECD9F7448Q36715535-F583CE6C-2176-46CC-8084-57637F77AEA5Q36779189-69063839-E783-466E-ABA2-62FFCA1EFAF7Q36957000-CE08372A-FBF0-4679-9C26-A990F68F8436Q37399718-9FF9EA65-E07F-4CFD-BA82-5E89E55A8B16Q37446146-3344EE05-4459-4097-A729-AFB47783B067Q37520458-5BAB7ACB-ACBB-453C-8096-F565BBD35BECQ37523747-86C869D8-5D5D-4C7A-A648-AAEDBAE5D10BQ37548314-31DC9D3C-50D7-42B0-A48E-B507CF0E7867Q37612662-B316C780-98C2-408F-AFF4-63D9E7A6A465Q37651851-EEECF593-6E90-47DD-B52E-4A90B6EA4631Q38396267-C2ECFBDC-05D2-4C8D-B75E-F63FADB6B7BFQ38806119-99DF81DB-FA32-4CE9-B5AE-BF1E71458E0B
P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Changshun Shao
@ast
Changshun Shao
@en
Changshun Shao
@es
Changshun Shao
@nl
Changshun Shao
@sl
type
label
Changshun Shao
@ast
Changshun Shao
@en
Changshun Shao
@es
Changshun Shao
@nl
Changshun Shao
@sl
prefLabel
Changshun Shao
@ast
Changshun Shao
@en
Changshun Shao
@es
Changshun Shao
@nl
Changshun Shao
@sl
P106
P1153
7102817023
P31
P496
0000-0003-2618-9342