Re-evaluation of how artemisinins work in light of emerging evidence of in vitro resistance.
about
Erythrocyte G protein as a novel target for malarial chemotherapyArtemisinins: their growing importance in medicineGeographic structuring of the Plasmodium falciparum sarco(endo)plasmic reticulum Ca2+ ATPase (PfSERCA) gene diversityMining a cathepsin inhibitor library for new antiparasitic drug leadsIn vitro sensitivity of Plasmodium falciparum from China-Myanmar border area to major ACT drugs and polymorphisms in potential target genesCurrent status of artemisinin-resistant falciparum malaria in South Asia: a randomized controlled artesunate monotherapy trial in BangladeshGene encoding a deubiquitinating enzyme is mutated in artesunate- and chloroquine-resistant rodent malaria parasitesTransporters involved in resistance to antimalarial drugs.Spontaneous mutations in the Plasmodium falciparum sarcoplasmic/ endoplasmic reticulum Ca2+-ATPase (PfATP6) gene among geographically widespread parasite populations unexposed to artemisinin-based combination therapies.Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria.Artesunate tolerance in transgenic Plasmodium falciparum parasites overexpressing a tryptophan-rich protein.Discovery, mechanisms of action and combination therapy of artemisininMolecular markers of anti-malarial drug resistance in southwest Ethiopia over time: regional surveillance from 2006 to 2013.Lack of association of the S769N mutation in Plasmodium falciparum SERCA (PfATP6) with resistance to artemisinins.Drug-resistant malaria - an insight.Acute pancreatitis and subdural haematoma in a patient with severe falciparum malaria: case report and review of literature.Recent highlights in antimalarial drug resistance and chemotherapy research.Pharmacokinetics of the Antischistosomal Lead Ozonide OZ418 in Uninfected Mice Determined by Liquid Chromatography-Tandem Mass SpectrometryMalaria and iron: history and review.Multifunctional host defense peptides: antiparasitic activities.Toxicity of the antimalarial artemisinin and its dervatives.Synergistic effects of floral phytochemicals against a bumble bee parasite.Novel antimalarial drug targets: hope for new antimalarial drugs.Novel anti-malarial combinations and their toxicity.Quantification of dihydroartemisinin, artesunate and artemisinin in human blood: overcoming the technical challenge of protecting the peroxide bridge.In vitro evaluations of antimalarial drugs and their relevance to clinical outcomes.Stability of peroxide antimalarials in the presence of human hemoglobin.Relationship between antimalarial activity and heme alkylation for spiro- and dispiro-1,2,4-trioxolane antimalarials.Decreasing pfmdr1 copy number in plasmodium falciparum malaria heightens susceptibility to mefloquine, lumefantrine, halofantrine, quinine, and artemisinin.Mechanism of antimalarial action of the synthetic trioxolane RBX11160 (OZ277).Interaction of artemisinins with oxyhemoglobin Hb-FeII, Hb-FeII, carboxyHb-FeII, heme-FeII, and carboxyheme FeII: significance for mode of action and implications for therapy of cerebral malaria.Amodiaquine resistance is not related to rare findings of pfmdr1 gene amplifications in Kenya.
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P2860
Re-evaluation of how artemisinins work in light of emerging evidence of in vitro resistance.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
Re-evaluation of how artemisin ...... idence of in vitro resistance.
@en
Re-evaluation of how artemisin ...... idence of in vitro resistance.
@nl
type
label
Re-evaluation of how artemisin ...... idence of in vitro resistance.
@en
Re-evaluation of how artemisin ...... idence of in vitro resistance.
@nl
prefLabel
Re-evaluation of how artemisin ...... idence of in vitro resistance.
@en
Re-evaluation of how artemisin ...... idence of in vitro resistance.
@nl
P2860
P50
P1476
Re-evaluation of how artemisin ...... idence of in vitro resistance.
@en
P2093
Charles J Woodrow
Odile Mercereau-Puijalon
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P304
P356
10.1016/J.MOLMED.2006.03.005
P577
2006-04-17T00:00:00Z