ENaC proteolytic regulation by channel-activating protease 2.
about
ENaC regulation by proteases and shear stressActivation of a latent nuclear localization signal in the NH2 terminus of γ-ENaC initiates feedback regulation of channel activity.Membrane-anchored serine proteases in vertebrate cell and developmental biologyNew role for plasmin in sodium homeostasis.Regulation of sodium transport by ENaC in the kidneyExtracellular allosteric regulatory subdomain within the gamma subunit of the epithelial Na+ channel.The cystic fibrosis transmembrane conductance regulator impedes proteolytic stimulation of the epithelial Na+ channel.Defining an inhibitory domain in the gamma subunit of the epithelial sodium channelThe epithelial sodium channel γ-subunit is processed proteolytically in human kidney.Proteolytic regulation of epithelial sodium channels by urokinase plasminogen activator: cutting edge and cleavage sites.Enhancement of alveolar epithelial sodium channel activity with decreased cystic fibrosis transmembrane conductance regulator expression in mouse lung.Sodium retention and volume expansion in nephrotic syndrome: implications for hypertension.TMPRSS4-dependent activation of the epithelial sodium channel requires cleavage of the γ-subunit distal to the furin cleavage siteEpithelial Sodium Channel-Mediated Sodium Transport Is Not Dependent on the Membrane-Bound Serine Protease CAP2/Tmprss4.ENaC-mediated alveolar fluid clearance and lung fluid balance depend on the channel-activating protease 1.Energetic and structural basis for activation of the epithelial sodium channel by matriptaseTissue kallikrein activation of the epithelial Na channelCathepsin B is secreted apically from Xenopus 2F3 cells and cleaves the epithelial sodium channel (ENaC) to increase its activity.Regional differences in rat conjunctival ion transport activitiesExpression of TMPRSS4 in non-small cell lung cancer and its modulation by hypoxia.Glandular Proteome Identifies Antiprotease Cystatin C as a Critical Modulator of Airway Hydration and Clearance.The cutting edge: membrane-anchored serine protease activities in the pericellular microenvironment.Membrane-anchored serine proteases in health and disease.ENaC at the cutting edge: regulation of epithelial sodium channels by proteases.Alternative mechanism of activation of the epithelial na+ channel by cleavage.Regulation of the epithelial Na+ channel and airway surface liquid volume by serine proteases.New pulmonary therapies directed at targets other than CFTR.The function and regulation of acid-sensing ion channels (ASICs) and the epithelial Na(+) channel (ENaC): IUPHAR Review 19.Cleavage of endogenous γENaC and elevated abundance of αENaC are associated with increased Na⁺ transport in response to apical fluid volume expansion in human H441 airway epithelial cells.Regulation of epithelial sodium channels in urokinase plasminogen activator deficiencyCutting it out: ENaC processing in the human nephron.Epithelial Na+ Channel Regulation by Extracellular and Intracellular Factors.Morpholino knockdown of the ubiquitously expressed transmembrane serine protease TMPRSS4a in zebrafish embryos exhibits severe defects in organogenesis and cell adhesion.
P2860
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P2860
ENaC proteolytic regulation by channel-activating protease 2.
description
2008 nî lūn-bûn
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2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
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2008年學術文章
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name
ENaC proteolytic regulation by channel-activating protease 2.
@en
ENaC proteolytic regulation by channel-activating protease 2.
@nl
type
label
ENaC proteolytic regulation by channel-activating protease 2.
@en
ENaC proteolytic regulation by channel-activating protease 2.
@nl
prefLabel
ENaC proteolytic regulation by channel-activating protease 2.
@en
ENaC proteolytic regulation by channel-activating protease 2.
@nl
P2093
P2860
P356
P1476
ENaC proteolytic regulation by channel-activating protease 2.
@en
P2093
Agustín García-Caballero
M Jackson Stutts
P2860
P304
P356
10.1085/JGP.200810030
P577
2008-10-13T00:00:00Z