Regulation of the epithelial sodium channel by serine proteases in human airways. - Test2 - elhamkhani - TriplyDB

Regulation of the epithelial sodium channel by serine proteases in human airways.

Regulation of the epithelial sodium channel by serine proteases in human airways.

http://www.wikidata.org/entity/Q30784493

about

Lipopolysaccharide hyperpolarizes guinea pig airway epithelium by increasing the activities of the epithelial Na+ channel and the Na+ - K+ pump A transmembrane serine protease is linked to the severe acute respiratory syndrome coronavirus receptor and activates virus entry The gene mutated in juvenile nephronophthisis type 4 encodes a novel protein that interacts with nephrocystin Mutations in SPINT2 cause a syndromic form of congenital sodium diarrhea Identification of the SPLUNC1 ENaC-inhibitory domain yields novel strategies to treat sodium hyperabsorption in cystic fibrosis airway epithelial cultures Airway surface liquid volume regulation determines different airway phenotypes in liddle compared with betaENaC-overexpressing mice SPLUNC1 regulates airway surface liquid volume by protecting ENaC from proteolytic cleavage Proteolytic activation of influenza viruses by serine proteases TMPRSS2 and HAT from human airway epithelium Early pulmonary inflammation and lung damage in children with cystic fibrosis Identification of hepatocyte growth factor activator inhibitor-1B as a potential physiological inhibitor of prostasin Prostasin regulates epithelial monolayer function: cell-specific Gpld1-mediated secretion and functional role for GPI anchor.Modeling and Simulation of Mucus Flow in Human Bronchial Epithelial Cell Cultures - Part I: Idealized Axisymmetric Swirling Flow Cloning and characterization of a transmembrane-type serine protease from rat kidney, a new sodium channel activator CFTR delivery to 25% of surface epithelial cells restores normal rates of mucus transport to human cystic fibrosis airway epithelium Cleavage of influenza virus hemagglutinin by airway proteases TMPRSS2 and HAT differs in subcellular localization and susceptibility to protease inhibitors Inhibition of influenza virus infection in human airway cell cultures by an antisense peptide-conjugated morpholino oligomer targeting the hemagglutinin-activating protease TMPRSS2.Efficient activation of the severe acute respiratory syndrome coronavirus spike protein by the transmembrane protease TMPRSS2.A segment of gamma ENaC mediates elastase activation of Na+ transport The host protease TMPRSS2 plays a major role in in vivo replication of emerging H7N9 and seasonal influenza viruses.ENaC-mediated effects assessed by MRI in a rat model of hypertonic saline-induced lung hydration.Inhibition of lung fluid clearance and epithelial Na+ channels by chlorine, hypochlorous acid, and chloramines.Activation of a latent nuclear localization signal in the NH2 terminus of γ-ENaC initiates feedback regulation of channel activity.TMPRSS2, a serine protease expressed in the prostate on the apical surface of luminal epithelial cells and released into semen in prostasomes, is misregulated in prostate cancer cells Purinergic receptors in airway epithelia.Regulation of the epithelial sodium channel (ENaC) by membrane trafficking Adenovirus-mediated human prostasin gene delivery is linked to increased aldosterone production and hypertension in rats.SPLUNC1 expression reduces surface levels of the epithelial sodium channel (ENaC) in Xenopus laevis oocytes.Phenotypic analysis of mice lacking the Tmprss2-encoded protease Prostasin, a membrane-anchored serine peptidase, regulates sodium currents in JME/CF15 cells, a cystic fibrosis airway epithelial cell line.The epithelial sodium channel (ENaC) establishes a trafficking vesicle pool responsible for its regulation Prostasin interacts with the epithelial Na+ channel and facilitates cleavage of the γ-subunit by a second protease Regulation of endogenous ENaC functional expression by CFTR and ΔF508-CFTR in airway epithelial cells.Activation of the epithelial sodium channel by the metalloprotease meprin β subunit.Urinary prostasin in humans: relationships among prostasin, aldosterone and epithelial sodium channel activity.Functional analysis of a missense mutation in the serine protease inhibitor SPINT2 associated with congenital sodium diarrhea.Enhancement of alveolar epithelial sodium channel activity with decreased cystic fibrosis transmembrane conductance regulator expression in mouse lung.Intracellular Na+ regulates epithelial Na+ channel maturation.Prostasin: An Epithelial Sodium Channel Regulator.Inositol polyphosphate derivative inhibits Na+ transport and improves fluid dynamics in cystic fibrosis airway epithelia.Impact of host proteases on reovirus infection in the respiratory tract.

P2860

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P2860

Regulation of the epithelial sodium channel by serine proteases in human airways.

http://www.wikidata.org/entity/Q30784493

description

2001 nî lūn-bûn

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2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2001年の論文

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2001年論文

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2001年論文

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2001年論文

@zh-hk

2001年論文

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2001年論文

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2001年论文

@wuu

name

Regulation of the epithelial sodium channel by serine proteases in human airways.

@ast

Regulation of the epithelial sodium channel by serine proteases in human airways.

@en

type

label

Regulation of the epithelial sodium channel by serine proteases in human airways.

@ast

Regulation of the epithelial sodium channel by serine proteases in human airways.

@en

prefLabel

Regulation of the epithelial sodium channel by serine proteases in human airways.

@ast

Regulation of the epithelial sodium channel by serine proteases in human airways.

@en

P1433

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P1433

Journal of Biological Chemistry

P1476

Regulation of the epithelial sodium channel by serine proteases in human airways.

@en

P2093

Andrew Hirsh

http://www.w3.org/2001/XMLSchema#string

Dong Chen Li

http://www.w3.org/2001/XMLSchema#string

Ginger Holloway

http://www.w3.org/2001/XMLSchema#string

Julie Chao

http://www.w3.org/2001/XMLSchema#string

Richard C Boucher

http://www.w3.org/2001/XMLSchema#string

Scott H Donaldson

http://www.w3.org/2001/XMLSchema#string

Sherif E Gabriel

http://www.w3.org/2001/XMLSchema#string

P2860

Evidence for periciliary liquid layer depletion, not abnormal ion composition, in the pathogenesis of cystic fibrosis airways disease

Identification and cloning of human placental bikunin, a novel serine protease inhibitor containing two Kunitz domains

Cloning of the TMPRSS2 gene, which encodes a novel serine protease with transmembrane, LDLRA, and SRCR domains and maps to 21q22.3

Purification and cloning of hepatocyte growth factor activator inhibitor type 2, a Kunitz-type serine protease inhibitor

Molecular cloning, tissue-specific expression, and cellular localization of human prostasin mRNA

Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits

Defective regulation of the epithelial Na+ channel by Nedd4 in Liddle's syndrome.

Prostasin is a glycosylphosphatidylinositol-anchored active serine protease.

Coordinated clearance of periciliary liquid and mucus from airway surfaces.

An epithelial serine protease activates the amiloride-sensitive sodium channel.

P304

8338-8345

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scholarly article

P356

10.1074/JBC.M105044200

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10

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P478

277

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2001-12-26T00:00:00Z

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11602062

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P698

11756432

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