Novel pyrimidine-2,4-diamine derivative suppresses the cell viability and spindle assembly checkpoint activity by targeting Aurora kinases.

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Novel pyrimidine-2,4-diamine derivative suppresses the cell viability and spindle assembly checkpoint activity by targeting Aurora kinases.

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2012 nî lūn-bûn

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年學術文章

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2012年學術文章

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Novel pyrimidine-2,4-diamine d ...... y by targeting Aurora kinases.

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Novel pyrimidine-2,4-diamine d ...... y by targeting Aurora kinases.

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Item

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Novel pyrimidine-2,4-diamine d ...... y by targeting Aurora kinases.

@en

Novel pyrimidine-2,4-diamine d ...... y by targeting Aurora kinases.

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Novel pyrimidine-2,4-diamine d ...... y by targeting Aurora kinases.

@en

Novel pyrimidine-2,4-diamine d ...... y by targeting Aurora kinases.

@nl

P1476

Novel pyrimidine-2,4-diamine d ...... y by targeting Aurora kinases.

@en

P2093

Anna-Leena Salmela

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Jenni Mäki-Jouppila

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Lila Kallio

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Pauliina Toivonen

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P2860

Shugoshin 1 plays a central role in kinetochore assembly and is required for kinetochore targeting of Plk1

Lethality to human cancer cells through massive chromosome loss by inhibition of the mitotic checkpoint.

CENP-A is phosphorylated by Aurora B kinase and plays an unexpected role in completion of cytokinesis

The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint

Molecular basis of drug resistance in aurora kinases

A class of 2,4-bisanilinopyrimidine Aurora A inhibitors with unusually high selectivity against Aurora B

The spindle-assembly checkpoint in space and time

The mitotic serine/threonine kinase Aurora2/AIK is regulated by phosphorylation and degradation

Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen

Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores

P304

436-445

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P31

scholarly article

P356

10.1093/CARCIN/BGS339

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P407

English

P433

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P478

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P50

Pekka Kohonen

Jeroen Pouwels

Marko J. Kallio

P577

2012-10-26T00:00:00Z

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P698

23104179

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