Discovery of a new class of inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase B by biology-oriented synthesis.
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The Chiral Pool in the Pictet-Spengler Reaction for the Synthesis of β-CarbolinesBioactivity-guided mapping and navigation of chemical space.Discovery of new antimalarial chemotypes through chemical methodology and library developmentBiology-oriented synthesis.Design and synthesis of nonpeptidic, small molecule inhibitors for the Mycobacterium tuberculosis protein tyrosine phosphatase PtpBA facile hydroxyindole carboxylic acid based focused library approach for potent and selective inhibitors of Mycobacterium protein tyrosine phosphatase BBio-inspired synthesis yields a tricyclic indoline that selectively resensitizes methicillin-resistant Staphylococcus aureus (MRSA) to β-lactam antibioticsAsperlones A and B, dinaphthalenone derivatives from a mangrove endophytic fungus Aspergillus sp. 16-5C.Double click reaction for the acquisition of a highly potent and selective mPTPB inhibitorCefsulodin Inspired Potent and Selective Inhibitors of mPTPB, a Virulent Phosphatase from Mycobacterium tuberculosis.Discovery and evaluation of novel inhibitors of mycobacterium protein tyrosine phosphatase B from the 6-Hydroxy-benzofuran-5-carboxylic acid scaffold.Allosteric regulation of proteases.Synthesis of natural product inspired compound collections.New strategies in fighting TB: targeting Mycobacterium tuberculosis-secreted phosphatases MptpA & MptpB.Nature-inspired stereospecific total synthesis of P-(+)-dispegatrine and four other monomeric sarpagine indole alkaloids.Enantioselective Organocatalytic Synthesis of a Secoyohimbane-Inspired Compound Collection with Neuritogenic Activity.Scaffold Diversity Synthesis and Its Application in Probe and Drug Discovery.Synthesis of diverse indole libraries on polystyrene resin - Scope and limitations of an organometallic reaction on solid supports.Stereospecific approach to the synthesis of ring-A oxygenated sarpagine indole alkaloids. Total synthesis of the dimeric indole alkaloid P-(+)-dispegatrine and six other monomeric indole alkaloids.Diversity-Oriented Synthesis for Novel, Selective and Drug-like Inhibitors for a Phosphatase from Mycobacterium Tuberculosis.Traceless solid phase synthesis of natural product inspired cis-1,2-dehydrodecalins.Silver catalyzed cascade synthesis of alkaloid ring systems: concise total synthesis of fascaplysin, homofascaplysin C and analogues.Biology-oriented combined solid- and solution-phase synthesis of a macroline-like compound collection.Enantioselective Friedel-Crafts alkylation of indoles with alkylidene malonates catalyzed by N,N'-dioxide-scandium(III) complexes: asymmetric synthesis of beta-carbolines.Enantioselective, protecting-group-free total synthesis of sarpagine alkaloids--a generalized approach.A switchable two-photon membrane tracer capable of imaging membrane-associated protein tyrosine phosphatase activities.Catalytic enantioselective synthesis of functionalized tropanes reveals novel inhibitors of hedgehog signaling.Catalytic Aerobic Oxidation and Tandem Enantioselective Cycloaddition in Cascade Multicomponent SynthesisA Scaffold-Tree-Merging Strategy for Prospective Bioactivity Annotation of γ-Pyrones
P2860
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P2860
Discovery of a new class of inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase B by biology-oriented synthesis.
description
2008 nî lūn-bûn
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2008年の論文
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2008年学术文章
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2008年学术文章
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2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
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2008年學術文章
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2008年學術文章
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name
Discovery of a new class of in ...... by biology-oriented synthesis.
@en
Discovery of a new class of in ...... by biology-oriented synthesis.
@nl
type
label
Discovery of a new class of in ...... by biology-oriented synthesis.
@en
Discovery of a new class of in ...... by biology-oriented synthesis.
@nl
prefLabel
Discovery of a new class of in ...... by biology-oriented synthesis.
@en
Discovery of a new class of in ...... by biology-oriented synthesis.
@nl
P2093
P2860
P356
P1476
Discovery of a new class of in ...... by biology-oriented synthesis.
@en
P2093
Andrea Nören-Müller
Krishna Saxena
Markus Kaiser
Wolfram Wilk
P2860
P304
P356
10.1002/ANIE.200801566
P407
P577
2008-01-01T00:00:00Z