A Scaffold-Tree-Merging Strategy for Prospective Bioactivity Annotation of γ-Pyrones
about
Impairment of prostate cancer cell growth by a selective and reversible lysine-specific demethylase 1 inhibitor.Visual Analysis of Biological Activity Data with Scaffold Hunter.Recent trends and observations in the design of high-quality screening collections.Biology-oriented synthesis.Toward an efficient approach to identify molecular scaffolds possessing selective or promiscuous compounds.Synthesis and SAR of Lehualide B: a marine-derived natural product with potent anti-multiple myeloma activity.Histone Lysine Demethylase Inhibitors.In silico target fishing for the potential targets and molecular mechanisms of baicalein as an antiparkinsonian agent: discovery of the protective effects on NMDA receptor-mediated neurotoxicity.Rational development of Stafib-2: a selective, nanomolar inhibitor of the transcription factor STAT5b.Nanomolar inhibitors of the transcription factor STAT5b with high selectivity over STAT5aScaffold Hunter: a comprehensive visual analytics framework for drug discovery.Development of Erasin: a chromone-based STAT3 inhibitor which induces apoptosis in Erlotinib-resistant lung cancer cells.Synthesis and evaluation of xanthone derivatives as acid sphingomyelinase inhibitors: potential treatment for UV-induced skin damage.Biology-Oriented Synthesis of a Withanolide-Inspired Compound Collection Reveals Novel Modulators of Hedgehog Signaling
P2860
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P2860
A Scaffold-Tree-Merging Strategy for Prospective Bioactivity Annotation of γ-Pyrones
description
scientific article published on 01 May 2010
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована у квітні 2010
@uk
name
A Scaffold-Tree-Merging Strategy for Prospective Bioactivity Annotation of γ-Pyrones
@en
A Scaffold-Tree-Merging Strategy for Prospective Bioactivity Annotation of γ-Pyrones
@nl
type
label
A Scaffold-Tree-Merging Strategy for Prospective Bioactivity Annotation of γ-Pyrones
@en
A Scaffold-Tree-Merging Strategy for Prospective Bioactivity Annotation of γ-Pyrones
@nl
prefLabel
A Scaffold-Tree-Merging Strategy for Prospective Bioactivity Annotation of γ-Pyrones
@en
A Scaffold-Tree-Merging Strategy for Prospective Bioactivity Annotation of γ-Pyrones
@nl
P2093
P2860
P50
P356
P1476
A scaffold-tree-merging strategy for prospective bioactivity annotation of gamma-pyrones
@en
P2093
Anke G Roth
Athanassios Giannis
Aybike Yektaoglu
Bianca Sperl
Markus Kaiser
Samy Chammaa
Stefan Wetzel
Steffen Renner
Thorsten Berg
Wolfram Wilk
P2860
P304
P356
10.1002/ANIE.200906555
P407
P577
2010-05-01T00:00:00Z