Par3 and aPKC regulate BACE1 endosome-to-TGN trafficking through PACS1.

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The physical approximation of APP and BACE-1: A key event in alzheimer's disease pathogenesis.

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P2860

Par3 and aPKC regulate BACE1 endosome-to-TGN trafficking through PACS1.

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http://www.wikidata.org/entity/Q47747110

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

@wuu

2017年学术文章

@zh-cn

2017年学术文章

@zh-hans

2017年学术文章

@zh-my

2017年学术文章

@zh-sg

2017年學術文章

@yue

2017年學術文章

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2017年學術文章

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name

Par3 and aPKC regulate BACE1 endosome-to-TGN trafficking through PACS1.

@en

Par3 and aPKC regulate BACE1 endosome-to-TGN trafficking through PACS1.

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type

Item

label

Par3 and aPKC regulate BACE1 endosome-to-TGN trafficking through PACS1.

@en

Par3 and aPKC regulate BACE1 endosome-to-TGN trafficking through PACS1.

@nl

prefLabel

Par3 and aPKC regulate BACE1 endosome-to-TGN trafficking through PACS1.

@en

Par3 and aPKC regulate BACE1 endosome-to-TGN trafficking through PACS1.

@nl

P1476

Par3 and aPKC regulate BACE1 endosome-to-TGN trafficking through PACS1.

@en

P2093

Huaye Zhang

http://www.w3.org/2001/XMLSchema#string

Miao Sun

http://www.w3.org/2001/XMLSchema#string

P2860

The Amyloid Precursor Protein is rapidly transported from the Golgi apparatus to the lysosome and where it is processed into beta-amyloid.

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

Alzheimer amyloid protein precursor in the rat hippocampus: transport and processing through the perforant path

Interaction of the cytosolic domains of sorLA/LR11 with the amyloid precursor protein (APP) and beta-secretase beta-site APP-cleaving enzyme

A PACS-1, GGA3 and CK2 complex regulates CI-MPR trafficking

Two endoplasmic reticulum (ER)/ER Golgi intermediate compartment-based lysine acetyltransferases post-translationally regulate BACE1 levels

GGA1-mediated endocytic traffic of LR11/SorLA alters APP intracellular distribution and amyloid-β production

Amyloid beta peptide load is correlated with increased beta-secretase activity in sporadic Alzheimer's disease patients

Retromer deficiency observed in Alzheimer's disease causes hippocampal dysfunction, neurodegeneration, and Abeta accumulation

The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease

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129-140

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scholarly article

P356

10.1016/J.NEUROBIOLAGING.2017.08.024

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http://www.w3.org/2001/XMLSchema#string

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2017-09-21T00:00:00Z

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28946017

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5653456

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Par3 and aPKC regulate BACE1 endosome-to-TGN trafficking through PACS1.

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P2860

P2860

Par3 and aPKC regulate BACE1 endosome-to-TGN trafficking through PACS1.

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type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P478

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P478

P577

P698

P932