The synucleins: a family of proteins involved in synaptic function, plasticity, neurodegeneration and disease.
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Structures of the E46K mutant-type α-synuclein protein and impact of E46K mutation on the structures of the wild-type α-synuclein proteinThe synaptic pathology of alpha-synuclein aggregation in dementia with Lewy bodies, Parkinson's disease and Parkinson's disease dementiaDequalinium-induced protofibril formation of alpha-synucleinThe chaperone-like protein 14-3-3η interacts with human α-synuclein aggregation intermediates rerouting the amyloidogenic pathway and reducing α-synuclein cellular toxicitySynaptic vesicle trafficking and Parkinson's diseaseAlpha-synuclein and polyunsaturated fatty acids promote clathrin-mediated endocytosis and synaptic vesicle recyclingUpregulation of alpha-synuclein by lipopolysaccharide and interleukin-1 in human macrophagesMitochondrial lipid abnormality and electron transport chain impairment in mice lacking alpha-synucleinAlpha-synuclein promotes SNARE-complex assembly in vivo and in vitroNeuropathology of non-Alzheimer degenerative disordersResidual structure, backbone dynamics, and interactions within the synuclein familyParkin counteracts symptoms in a Drosophila model of Parkinson's disease.Native α-synuclein induces clustering of synaptic-vesicle mimics via binding to phospholipids and synaptobrevin-2/VAMP2Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functionsUnfolded Protein Response and Macroautophagy in Alzheimer's, Parkinson's and Prion DiseasesAdult Astrogenesis and the Etiology of Cortical NeurodegenerationRedox control of protein degradationAdult hippocampal neurogenesis in Parkinson's disease: impact on neuronal survival and plasticityAlpha-synuclein biology in Lewy body diseasesalpha-Synuclein produces a long-lasting increase in neurotransmitter releaseProteomics of the injured rat sciatic nerve reveals protein expression dynamics during regenerationα-Synuclein negatively regulates protein kinase Cδ expression to suppress apoptosis in dopaminergic neurons by reducing p300 histone acetyltransferase activityAlpha-synuclein involvement in hippocampal synaptic plasticity: role of NO, cGMP, cGK and CaMKIIThe effect of music performance on the transcriptome of professional musicians.Biophysics of α-synuclein membrane interactions.Biophysical insights into how surfaces, including lipid membranes, modulate protein aggregation related to neurodegeneration.A β-synuclein mutation linked to dementia produces neurodegeneration when expressed in mouse brainHypokinesia and reduced dopamine levels in zebrafish lacking β- and γ1-synucleins.Highly conserved and disease-specific patterns of carboxyterminally truncated Abeta peptides 1-37/38/39 in addition to 1-40/42 in Alzheimer's disease and in patients with chronic neuroinflammation.Novel leptin-regulated genes revealed by transcriptional profiling of the hypothalamic paraventricular nucleus.Biophysics of Parkinson's disease: structure and aggregation of alpha-synuclein.Synuclein gamma predicts poor clinical outcome in colon cancer with normal levels of carcinoembryonic antigenPartial regulation of serotonin transporter function by gamma-synuclein.CSF from Parkinson disease patients differentially affects cultured microglia and astrocytes.Tryptophan probes at the alpha-synuclein and membrane interface.Serine 129 phosphorylation reduces the ability of alpha-synuclein to regulate tyrosine hydroxylase and protein phosphatase 2A in vitro and in vivo.Membrane association and protein conformation of alpha-synuclein in intact neurons. Effect of Parkinson's disease-linked mutations.beta-amyloid peptides enhance alpha-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease.Baicalein reduces E46K alpha-synuclein aggregation in vitro and protects cells against E46K alpha-synuclein toxicity in cell models of familiar Parkinsonism.Synuclein gamma stimulates membrane-initiated estrogen signaling by chaperoning estrogen receptor (ER)-alpha36, a variant of ER-alpha.
P2860
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P2860
The synucleins: a family of proteins involved in synaptic function, plasticity, neurodegeneration and disease.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh-hant
name
The synucleins: a family of pr ...... neurodegeneration and disease.
@en
The synucleins: a family of pr ...... neurodegeneration and disease.
@nl
type
label
The synucleins: a family of pr ...... neurodegeneration and disease.
@en
The synucleins: a family of pr ...... neurodegeneration and disease.
@nl
prefLabel
The synucleins: a family of pr ...... neurodegeneration and disease.
@en
The synucleins: a family of pr ...... neurodegeneration and disease.
@nl
P1476
The synucleins: a family of pr ...... neurodegeneration and disease.
@en
P304
P356
10.1016/S0166-2236(97)01213-7
P577
1998-06-01T00:00:00Z