The voltage-gated Kv1.3 K(+) channel in effector memory T cells as new target for MS - Wikidata - thesis-toulmin - TriplyDB

The voltage-gated Kv1.3 K(+) channel in effector memory T cells as new target for MS

The voltage-gated Kv1.3 K(+) channel in effector memory T cells as new target for MS

http://www.wikidata.org/entity/Q24675746

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Clofazimine inhibits human Kv1.3 potassium channel by perturbing calcium oscillation in T lymphocytes The voltage-gated potassium channel Kv1.3 is highly expressed on inflammatory infiltrates in multiple sclerosis brain Kv1.3 potassium channels are localized in the immunological synapse formed between cytotoxic and target cells A C-terminally amidated analogue of ShK is a potent and selective blocker of the voltage-gated potassium channel Kv1.3 Imaging of effector memory T cells during a delayed-type hypersensitivity reaction and suppression by Kv1.3 channel block.K+ channels as targets for specific immunomodulation The intermediate-conductance calcium-activated potassium channel KCa3.1 contributes to atherogenesis in mice and humans Engineering a stable and selective peptide blocker of the Kv1.3 channel in T lymphocytes Phosphatidylinositol-3 phosphatase myotubularin-related protein 6 negatively regulates CD4 T cells Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases Targeting effector memory T cells with the small molecule Kv1.3 blocker PAP-1 suppresses allergic contact dermatitis Ion channels and transporters in lymphocyte function and immunity Computational studies of marine toxins targeting ion channels Preferential uptake of antioxidant carbon nanoparticles by T lymphocytes for immunomodulation.Kv1.3 channel-blocking immunomodulatory peptides from parasitic worms: implications for autoimmune diseases Lymphocyte Kv1.3-channels in the pathogenesis of chronic obstructive pulmonary disease: novel therapeutic implications of targeting the channels by commonly used drugs Multiple Sclerosis and T Lymphocytes: An Entangled Story Potassium channel-blockers as therapeutic agents to interfere with bone resorption of periodontal disease Potassium channels, memory T cells, and multiple sclerosis Potent suppression of vascular smooth muscle cell migration and human neointimal hyperplasia by KV1.3 channel blockers Targeting effector memory T cells with a selective peptide inhibitor of Kv1.3 channels for therapy of autoimmune diseases The antibody targeting the E314 peptide of human Kv1.3 pore region serves as a novel, potent and specific channel blocker K(Ca)3.1 channel-blockade attenuates airway pathophysiology in a sheep model of chronic asthma Peptidomimetic Star Polymers for Targeting Biological Ion Channels The C-terminus SH3-binding domain of Kv1.3 is required for the actin-mediated immobilization of the channel via cortactin TASK1 modulates inflammation and neurodegeneration in autoimmune inflammation of the central nervous system.Modeling and simulation of ion channels.The Ca(2+)-activated K(+) channel KCa3.1 compartmentalizes in the immunological synapse of human T lymphocytes.Study of membrane potential in T lymphocytes subpopulations using flow cytometry.Blocking KV1.3 channels inhibits Th2 lymphocyte function and treats a rat model of asthma Helminth Immunomodulation in Autoimmune Disease.Selected microRNAs define cell fate determination of murine central memory CD8 T cells.Inhibition of the K+ channel KCa3.1 ameliorates T cell-mediated colitis Kv1.3 channel blocker (ImKTx88) maintains blood-brain barrier in experimental autoimmune encephalomyelitis.Autoimmune effector memory T cells: the bad and the good A systems pharmacology-based approach to identify novel Kv1.3 channel-dependent mechanisms in microglial activation T-lymphocyte Kv1.3 channel activation triggers the NLRP3 inflammasome signaling pathway in hypertensive patients Binding modes of two scorpion toxins to the voltage-gated potassium channel kv1.3 revealed from molecular dynamics.Oxidative modulation of voltage-gated potassium channels.Natural products and ion channel pharmacology

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P2860

The voltage-gated Kv1.3 K(+) channel in effector memory T cells as new target for MS

http://www.wikidata.org/entity/Q24675746

description

2003 nî lūn-bûn

@nan

2003 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի հունիսին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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name

The voltage-gated Kv1.3 K(+) channel in effector memory T cells as new target for MS

@ast

The voltage-gated Kv1.3 K(+) channel in effector memory T cells as new target for MS

@en

The voltage-gated Kv1.3 K(+) channel in effector memory T cells as new target for MS

@nl

type

label

The voltage-gated Kv1.3 K(+) channel in effector memory T cells as new target for MS

@ast

The voltage-gated Kv1.3 K(+) channel in effector memory T cells as new target for MS

@en

The voltage-gated Kv1.3 K(+) channel in effector memory T cells as new target for MS

@nl

prefLabel

The voltage-gated Kv1.3 K(+) channel in effector memory T cells as new target for MS

@ast

The voltage-gated Kv1.3 K(+) channel in effector memory T cells as new target for MS

@en

The voltage-gated Kv1.3 K(+) channel in effector memory T cells as new target for MS

@nl

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Journal of Clinical Investigation

P1476

The voltage-gated Kv1.3 K(+) channel in effector memory T cells as new target for MS

@en

P2093

Christine Beeton

http://www.w3.org/2001/XMLSchema#string

Heike Wulff

http://www.w3.org/2001/XMLSchema#string

K George Chandy

http://www.w3.org/2001/XMLSchema#string

Michael Pennington

http://www.w3.org/2001/XMLSchema#string

Rameeza Allie

http://www.w3.org/2001/XMLSchema#string

Sung Yun

http://www.w3.org/2001/XMLSchema#string

P2860

Expression and chromosomal localization of a lymphocyte K+ channel gene

Selective blockade of T lymphocyte K(+) channels ameliorates experimental autoimmune encephalomyelitis, a model for multiple sclerosis

CD4+CD28- costimulation-independent T cells in multiple sclerosis

Design of a potent and selective inhibitor of the intermediate-conductance Ca2+-activated K+ channel, IKCa1: a potential immunosuppressant

Voltage-gated potassium channels are required for human T lymphocyte activation

ShK-Dap22, a potent Kv1.3-specific immunosuppressive polypeptide

Correolide and derivatives are novel immunosuppressants blocking the lymphocyte Kv1.3 potassium channels

Up-regulation of the IKCa1 potassium channel during T-cell activation. Molecular mechanism and functional consequences

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

Blockade of the voltage-gated potassium channel Kv1.3 inhibits immune responses in vivo

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1703-13

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scholarly article

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1755216

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10.1172/JCI16921

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11

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111

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Peter A Calabresi

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2003-06-01T00:00:00Z

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12782673

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156104

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