Structural and functional analyses of disease-causing missense mutations in Bloom syndrome protein
about
Unwinding and rewinding: double faces of helicase?Phenotypes and genotypes of the chromosomal instability syndromesDisease-causing missense mutations in human DNA helicase disordersThe role of RecQ helicases in non-homologous end-joiningStructure and function of the regulatory HRDC domain from human Bloom syndrome proteinStructure of human Bloom's syndrome helicase in complex with ADP and duplex DNAThe mechanosensory structure of the hair cell requires clarin-1, a protein encoded by Usher syndrome III causative geneCrystal structure of the Bloom's syndrome helicase indicates a role for the HRDC domain in conformational changesBloom's syndrome and PICH helicases cooperate with topoisomerase IIα in centromere disjunction before anaphaseVasohibin-1 is identified as a master-regulator of endothelial cell apoptosis using gene network analysisUnwinding forward and sliding back: an intermittent unwinding mode of the BLM helicase.BLM unfolds G-quadruplexes in different structural environments through different mechanismsDNA helicases associated with genetic instability, cancer, and aging.The Q motif of Fanconi anemia group J protein (FANCJ) DNA helicase regulates its dimerization, DNA binding, and DNA repair function.Multimeric BLM is dissociated upon ATP hydrolysis and functions as monomers in resolving DNA structuresNon-Bloom syndrome-associated partial and total loss-of-function variants of BLM helicase.Cellular defects caused by hypomorphic variants of the Bloom syndrome helicase gene BLM.The BLM dissolvasome in DNA replication and repair.A 3'-5' exonuclease activity embedded in the helicase core domain of Candida albicans Pif1 helicase.Homozygosity for the WRN Helicase-Inactivating Variant, R834C, does not confer a Werner syndrome clinical phenotype.Probing Genome Maintenance Functions of human RECQ1.Pyrimidine pool imbalance induced by BLM helicase deficiency contributes to genetic instability in Bloom syndrome.Processive translocation mechanism of the human Bloom's syndrome helicase along single-stranded DNA.The Pif1 signature motif of Pfh1 is necessary for both protein displacement and helicase unwinding activities, but is dispensable for strand-annealing activity
P2860
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P2860
Structural and functional analyses of disease-causing missense mutations in Bloom syndrome protein
description
2007 nî lūn-bûn
@nan
2007 թուականին հրատարակուած գիտական յօդուած
@hyw
2007 թվականին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Structural and functional anal ...... ions in Bloom syndrome protein
@ast
Structural and functional anal ...... ions in Bloom syndrome protein
@en
Structural and functional anal ...... ions in Bloom syndrome protein
@en-gb
Structural and functional anal ...... ions in Bloom syndrome protein
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type
label
Structural and functional anal ...... ions in Bloom syndrome protein
@ast
Structural and functional anal ...... ions in Bloom syndrome protein
@en
Structural and functional anal ...... ions in Bloom syndrome protein
@en-gb
Structural and functional anal ...... ions in Bloom syndrome protein
@nl
prefLabel
Structural and functional anal ...... ions in Bloom syndrome protein
@ast
Structural and functional anal ...... ions in Bloom syndrome protein
@en
Structural and functional anal ...... ions in Bloom syndrome protein
@en-gb
Structural and functional anal ...... ions in Bloom syndrome protein
@nl
P2093
P2860
P356
P1476
Structural and functional anal ...... ions in Bloom syndrome protein
@en
P2093
Mounira Amor-Gueret
Peng-Ye Wang
Rong-Bing Guo
Shuo-Xing Dou
Xing-Dong Zhang
Xu Guang Xi
P2860
P304
P356
10.1093/NAR/GKM536
P407
P577
2007-09-18T00:00:00Z