Structure of human Bloom's syndrome helicase in complex with ADP and duplex DNA
about
Human HLTF mediates postreplication repair by its HIRAN domain-dependent replication fork remodelling.Crystal structure of the Bloom's syndrome helicase indicates a role for the HRDC domain in conformational changesA helical bundle in the N-terminal domain of the BLM helicase mediates dimer and potentially hexamer formation.Crystal structure of Deinococcus radiodurans RecQ helicase catalytic core domain: the interdomain flexibility.Structural mechanisms of DNA binding and unwinding in bacterial RecQ helicases.Unwinding forward and sliding back: an intermittent unwinding mode of the BLM helicase.The HRDC domain of E. coli RecQ helicase controls single-stranded DNA translocation and double-stranded DNA unwinding rates without affecting mechanoenzymatic coupling.BLM unfolds G-quadruplexes in different structural environments through different mechanismsCellular defects caused by hypomorphic variants of the Bloom syndrome helicase gene BLM.Mechanistic insight into cadmium-induced inactivation of the Bloom protein.Bloom's Syndrome: Clinical Spectrum, Molecular Pathogenesis, and Cancer Predisposition.Shuttling along DNA and directed processing of D-loops by RecQ helicase support quality control of homologous recombination.Single-molecule studies reveal reciprocating of WRN helicase core along ssDNA during DNA unwinding.Structural studies of DNA end detection and resection in homologous recombination.Grip it and rip it: structural mechanisms of DNA helicase substrate binding and unwinding.Structural mechanisms of human RecQ helicases WRN and BLM.Bloom's syndrome: Why not premature aging?: A comparison of the BLM and WRN helicases.The structural and functional characterization of human RecQ4 reveals insights into its helicase mechanism.Insights into the RecQ helicase mechanism revealed by the structure of the helicase domain of human RECQL5.RAD54 N-terminal domain is a DNA sensor that couples ATP hydrolysis with branch migration of Holliday junctions.Single molecule kinetics uncover roles for E. coli RecQ DNA helicase domains and interaction with SSB
P2860
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P2860
Structure of human Bloom's syndrome helicase in complex with ADP and duplex DNA
description
2014 nî lūn-bûn
@nan
2014 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
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name
Structure of human Bloom's syndrome helicase in complex with ADP and duplex DNA
@ast
Structure of human Bloom's syndrome helicase in complex with ADP and duplex DNA
@en
Structure of human Bloom's syndrome helicase in complex with ADP and duplex DNA
@nl
type
label
Structure of human Bloom's syndrome helicase in complex with ADP and duplex DNA
@ast
Structure of human Bloom's syndrome helicase in complex with ADP and duplex DNA
@en
Structure of human Bloom's syndrome helicase in complex with ADP and duplex DNA
@nl
prefLabel
Structure of human Bloom's syndrome helicase in complex with ADP and duplex DNA
@ast
Structure of human Bloom's syndrome helicase in complex with ADP and duplex DNA
@en
Structure of human Bloom's syndrome helicase in complex with ADP and duplex DNA
@nl
P2093
P2860
P3181
P1476
Structure of human Bloom's syndrome helicase in complex with ADP and duplex DNA
@en
P2093
Adam Tanner
Jay A Bertrand
John R Pollard
Julian M C Golec
Michael K Swan
Peter A Charlton
Philip M Reaper
Rebecca Bordas
Sarah Vial
Valerie Legris
P2860
P304
P3181
P356
10.1107/S139900471400501X
P577
2014-05-01T00:00:00Z