MO25 is a master regulator of SPAK/OSR1 and MST3/MST4/YSK1 protein kinases
about
STRAD pseudokinases regulate axogenesis and LKB1 stabilityThe WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+-Cl- co-transportersMST kinases in development and diseaseA molecular update on pseudohypoaldosteronism type IIMitotic exit and separation of mother and daughter cellsFungal communication requires the MAK-2 pathway elements STE-20 and RAS-2, the NRC-1 adapter STE-50 and the MAP kinase scaffold HAM-5The NDR kinase scaffold HYM1/MO25 is essential for MAK2 map kinase signaling in Neurospora crassaStructural insights into the activation of MST3 by MO25Structure of zebrafish MO25Domain-Swapping Switch Point in Ste20 Protein Kinase SPAKDiscovery of Diverse Small-Molecule Inhibitors of Mammalian Sterile20-like Kinase 3 (MST3)Structural and biochemical insights into the activation mechanisms of germinal center kinase OSR1.A novel Ste20-related proline/alanine-rich kinase (SPAK)-independent pathway involving calcium-binding protein 39 (Cab39) and serine threonine kinase with no lysine member 4 (WNK4) in the activation of Na-K-Cl cotransporters.Hypotonicity stimulates potassium flux through the WNK-SPAK/OSR1 kinase cascade and the Ncc69 sodium-potassium-2-chloride cotransporter in the Drosophila renal tubule.Kinase drug discovery--what's next in the field?Cation-chloride cotransporters in neuronal development, plasticity and diseaseSPAK deficiency corrects pseudohypoaldosteronism II caused by WNK4 mutation.Cell cycle regulated interaction of a yeast Hippo kinase and its activator MO25/Hym1A novel non-canonical mechanism of regulation of MST3 (mammalian Sterile20-related kinase 3).Discovery of Novel SPAK Inhibitors That Block WNK Kinase Signaling to Cation Chloride Transporters.Critical role of the SPAK protein kinase CCT domain in controlling blood pressureMolecular physiology of SPAK and OSR1: two Ste20-related protein kinases regulating ion transport.Towards the Development of Small-Molecule MO25 Binders as Potential Indirect SPAK/OSR1 Kinase Inhibitors.RNA-seq of life stages of the oomycete Phytophthora infestans reveals dynamic changes in metabolic, signal transduction, and pathogenesis genes and a major role for calcium signaling in development.SPAK isoforms and OSR1 regulate sodium-chloride co-transporters in a nephron-specific manner.Interactions with WNK (with no lysine) family members regulate oxidative stress response 1 and ion co-transporter activityProteomic responses to elevated ocean temperature in ovaries of the ascidian Ciona intestinalis.Calcium-binding protein 39 facilitates molecular interaction between Ste20p proline alanine-rich kinase and oxidative stress response 1 monomers.Regulation of the renal Na+-Cl- cotransporter by phosphorylation and ubiquitylation.The WNK/SPAK and IRBIT/PP1 pathways in epithelial fluid and electrolyte transportThe CUL3/KLHL3-WNK-SPAK/OSR1 pathway as a target for antihypertensive therapyHypertension: the missing WNKs.Regulation of OSR1 and the sodium, potassium, two chloride cotransporter by convergent signals.Functional kinomics establishes a critical node of volume-sensitive cation-Cl- cotransporter regulation in the mammalian brainPhysiology and pathophysiology of SLC12A1/2 transporters.WNK signalling pathways in blood pressure regulationGerminal center kinases in immune regulation.Exploring the intricate regulatory network controlling the thiazide-sensitive NaCl cotransporter (NCC).SOcK, MiSTs, MASK and STicKs: the GCKIII (germinal centre kinase III) kinases and their heterologous protein-protein interactions.The WNK-SPAK/OSR1 pathway: master regulator of cation-chloride cotransporters.
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P2860
MO25 is a master regulator of SPAK/OSR1 and MST3/MST4/YSK1 protein kinases
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
MO25 is a master regulator of SPAK/OSR1 and MST3/MST4/YSK1 protein kinases
@ast
MO25 is a master regulator of SPAK/OSR1 and MST3/MST4/YSK1 protein kinases
@en
MO25 is a master regulator of SPAK/OSR1 and MST3/MST4/YSK1 protein kinases
@en-gb
MO25 is a master regulator of SPAK/OSR1 and MST3/MST4/YSK1 protein kinases
@nl
type
label
MO25 is a master regulator of SPAK/OSR1 and MST3/MST4/YSK1 protein kinases
@ast
MO25 is a master regulator of SPAK/OSR1 and MST3/MST4/YSK1 protein kinases
@en
MO25 is a master regulator of SPAK/OSR1 and MST3/MST4/YSK1 protein kinases
@en-gb
MO25 is a master regulator of SPAK/OSR1 and MST3/MST4/YSK1 protein kinases
@nl
prefLabel
MO25 is a master regulator of SPAK/OSR1 and MST3/MST4/YSK1 protein kinases
@ast
MO25 is a master regulator of SPAK/OSR1 and MST3/MST4/YSK1 protein kinases
@en
MO25 is a master regulator of SPAK/OSR1 and MST3/MST4/YSK1 protein kinases
@en-gb
MO25 is a master regulator of SPAK/OSR1 and MST3/MST4/YSK1 protein kinases
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
MO25 is a master regulator of SPAK/OSR1 and MST3/MST4/YSK1 protein kinases
@en
P2093
Iva Navratilova
Lorna Plater
Paola de los Heros
Rachel Toth
Robert Gourlay
P2860
P304
P3181
P356
10.1038/EMBOJ.2011.78
P407
P577
2011-05-04T00:00:00Z