Phospholipase Cgamma activates Ras on the Golgi apparatus by means of RasGRP1
about
Selective regulation of tumor necrosis factor-induced Erk signaling by Src family kinases and the T cell protein tyrosine phosphataseIntracellular retention, degradation, and signaling of glycosylation-deficient FGFR2 and craniosynostosis syndrome-associated FGFR2C278FA diacylglycerol-protein kinase C-RasGRP1 pathway directs Ras activation upon antigen receptor stimulation of T cells.Akt binds to and phosphorylates phospholipase C-gamma1 in response to epidermal growth factorHeterotrimeric G protein-independent signaling of a G protein-coupled receptor. Direct binding of ARNO/cytohesin-2 to the carboxyl terminus of the A2A adenosine receptor is necessary for sustained activation of the ERK/MAP kinase pathwayPLC-gamma1 and Rac1 coregulate EGF-induced cytoskeleton remodeling and cell migrationYSK1 is activated by the Golgi matrix protein GM130 and plays a role in cell migration through its substrate 14-3-3zetaRasGRP1 is required for human NK cell functionSpatial regulation of Raf kinase signaling by RKTGPAQR10 and PAQR11 mediate Ras signaling in the Golgi apparatusMultiple sequence elements facilitate Chp Rho GTPase subcellular location, membrane association, and transforming activityActivation of RasGRP3 by phosphorylation of Thr-133 is required for B cell receptor-mediated Ras activationActivation of H-Ras in the endoplasmic reticulum by the RasGRF family guanine nucleotide exchange factorsRIAM regulates the cytoskeletal distribution and activation of PLC-gamma1 in T cellsAn essential role for RasGRP1 in mast cell function and IgE-mediated allergic responseRasGRF2, a guanosine nucleotide exchange factor for Ras GTPases, participates in T-cell signaling responsesUnusual interplay of two types of Ras activators, RasGRP and SOS, establishes sensitive and robust Ras activation in lymphocytesDasatinib sensitizes KRAS mutant colorectal tumors to cetuximabReceptor-mediated reversible translocation of the G protein betagamma complex from the plasma membrane to the Golgi complex.The PD1:PD-L1/2 Pathway from Discovery to Clinical ImplementationCsk-binding protein (Cbp) negatively regulates epidermal growth factor-induced cell transformation by controlling Src activationConvergence of cell cycle regulation and growth factor signals on GRASP65Identification and characterization of rain, a novel Ras-interacting protein with a unique subcellular localizationH-Ras and phosphoinositide 3-kinase cooperate to induce alpha(1,3)-fucosyltransferase VII expression in Jurkat T cellsInositol (1,4,5) trisphosphate 3 kinase B controls positive selection of T cells and modulates Erk activityRap1-mediated activation of extracellular signal-regulated kinases by cyclic AMP is dependent on the mode of Rap1 activationT-cell protein tyrosine phosphatase (Tcptp) is a negative regulator of colony-stimulating factor 1 signaling and macrophage differentiationRas plasma membrane signalling platformsCoordinating ERK/MAPK signalling through scaffolds and inhibitorsFatty acylation of proteins: The long and the short of it.Ras history: The saga continues.Raft protein clustering alters N-Ras membrane interactions and activation pattern.ShcA mediates the dominant pathway to extracellular signal-regulated kinase activation during early thymic developmentCa2+-dependent monomer and dimer formation switches CAPRI Protein between Ras GTPase-activating protein (GAP) and RapGAP activities.Identification of a Ras GTPase-activating protein regulated by receptor-mediated Ca2+ oscillations.Regulation of RasGRP1 function in T cell development and activation by its unique tail domain.Novel checkpoint response to genotoxic stress mediated by nucleolin-replication protein a complex formation.Identification of an alternatively spliced variant of Ca2+-promoted Ras inactivator as a possible regulator of RANKL shedding.Adaptor SKAP-55 binds p21 activating exchange factor RasGRP1 and negatively regulates the p21-ERK pathway in T-cells.Ras, an actor on many stages: posttranslational modifications, localization, and site-specified events.
P2860
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P2860
Phospholipase Cgamma activates Ras on the Golgi apparatus by means of RasGRP1
description
2003 nî lūn-bûn
@nan
2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
name
Phospholipase Cgamma activates Ras on the Golgi apparatus by means of RasGRP1
@ast
Phospholipase Cgamma activates Ras on the Golgi apparatus by means of RasGRP1
@en
Phospholipase Cgamma activates Ras on the Golgi apparatus by means of RasGRP1
@en-gb
Phospholipase Cgamma activates Ras on the Golgi apparatus by means of RasGRP1
@nl
type
label
Phospholipase Cgamma activates Ras on the Golgi apparatus by means of RasGRP1
@ast
Phospholipase Cgamma activates Ras on the Golgi apparatus by means of RasGRP1
@en
Phospholipase Cgamma activates Ras on the Golgi apparatus by means of RasGRP1
@en-gb
Phospholipase Cgamma activates Ras on the Golgi apparatus by means of RasGRP1
@nl
prefLabel
Phospholipase Cgamma activates Ras on the Golgi apparatus by means of RasGRP1
@ast
Phospholipase Cgamma activates Ras on the Golgi apparatus by means of RasGRP1
@en
Phospholipase Cgamma activates Ras on the Golgi apparatus by means of RasGRP1
@en-gb
Phospholipase Cgamma activates Ras on the Golgi apparatus by means of RasGRP1
@nl
P2093
P2860
P50
P921
P3181
P356
P1433
P1476
Phospholipase Cgamma activates Ras on the Golgi apparatus by means of RasGRP1
@en
P2093
Adrienne D Cox
Mark R Philips
Peter J Lockyer
Theresa M Grana
Trever G Bivona
P2860
P2888
P304
P3181
P356
10.1038/NATURE01806
P407
P577
2003-06-29T00:00:00Z
P6179
1006185831