Coupled in vitro import of U snRNPs and SMN, the spinal muscular atrophy protein
about
WRAP53 is essential for Cajal body formation and for targeting the survival of motor neuron complex to Cajal bodiesAbsence of gemin5 from SMN complexes in nuclear Cajal bodiesTim50a, a nuclear isoform of the mitochondrial Tim50, interacts with proteins involved in snRNP biogenesis.Gemin8 is a novel component of the survival motor neuron complex and functions in small nuclear ribonucleoprotein assemblyGemin8 is required for the architecture and function of the survival motor neuron complexDeficiency of the zinc finger protein ZPR1 causes defects in transcription and cell cycle progressionBiochemical and genetic evidence for a role of IGHMBP2 in the translational machineryZPR1 is essential for survival and is required for localization of the survival motor neurons (SMN) protein to Cajal bodies.Structural basis for m3G-cap-mediated nuclear import of spliceosomal UsnRNPs by snurportin1Cross-talk between snurportin1 subdomains.Gemin proteins are required for efficient assembly of Sm-class ribonucleoproteins.The Cajal body and histone locus bodyDephosphorylation of survival motor neurons (SMN) by PPM1G/PP2Cgamma governs Cajal body localization and stability of the SMN complexA stochastic view of spliceosome assembly and recycling in the nucleusStructural basis for m7G-cap hypermethylation of small nuclear, small nucleolar and telomerase RNA by the dimethyltransferase TGS1Gemin5 delivers snRNA precursors to the SMN complex for snRNP biogenesisIn vitro and in cellulo evidences for association of the survival of motor neuron complex with the fragile X mental retardation proteinIdentification of gemin5 as a novel 7-methylguanosine cap-binding proteinProlactin increases SMN expression and survival in a mouse model of severe spinal muscular atrophy via the STAT5 pathway.Unrip is a component of SMN complexes active in snRNP assemblyThe survival of motor neuron (SMN) protein interacts with the mRNA-binding protein HuD and regulates localization of poly(A) mRNA in primary motor neuron axons.Sm/Lsm genes provide a glimpse into the early evolution of the spliceosomeDynamic control of Cajal body number during zebrafish embryogenesis.Molecular determinants of survival motor neuron (SMN) protein cleavage by the calcium-activated protease, calpainMechanisms and signals for the nuclear import of proteinsA systematic RNAi synthetic interaction screen reveals a link between p53 and snoRNP assembly.Specific sequence features, recognized by the SMN complex, identify snRNAs and determine their fate as snRNPsWhole-genome screening identifies proteins localized to distinct nuclear bodiesThe C-terminal domain of coilin interacts with Sm proteins and U snRNPs.Tudor domains bind symmetrical dimethylated arginines.Depletion of SMN by RNA interference in HeLa cells induces defects in Cajal body formation.Pseudophosphorylated αB-crystallin is a nuclear chaperone imported into the nucleus with help of the SMN complexp38 Mitogen-activated protein kinase stabilizes SMN mRNA through RNA binding protein HuR.Arginine methylation of RNA-binding proteins regulates cell function and differentiationU bodies are cytoplasmic structures that contain uridine-rich small nuclear ribonucleoproteins and associate with P bodies.Oligomeric Properties of Survival Motor Neuron·Gemin2 ComplexesA Drosophila melanogaster model of spinal muscular atrophy reveals a function for SMN in striated muscle.NUFIP and the HSP90/R2TP chaperone bind the SMN complex and facilitate assembly of U4-specific proteins.Involvement of nuclear import and export factors in U8 box C/D snoRNP biogenesis.Cellular dynamics of small RNAs.
P2860
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P2860
Coupled in vitro import of U snRNPs and SMN, the spinal muscular atrophy protein
description
2004 nî lūn-bûn
@nan
2004 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Coupled in vitro import of U snRNPs and SMN, the spinal muscular atrophy protein
@ast
Coupled in vitro import of U snRNPs and SMN, the spinal muscular atrophy protein
@en
Coupled in vitro import of U snRNPs and SMN, the spinal muscular atrophy protein
@en-gb
Coupled in vitro import of U snRNPs and SMN, the spinal muscular atrophy protein
@nl
type
label
Coupled in vitro import of U snRNPs and SMN, the spinal muscular atrophy protein
@ast
Coupled in vitro import of U snRNPs and SMN, the spinal muscular atrophy protein
@en
Coupled in vitro import of U snRNPs and SMN, the spinal muscular atrophy protein
@en-gb
Coupled in vitro import of U snRNPs and SMN, the spinal muscular atrophy protein
@nl
prefLabel
Coupled in vitro import of U snRNPs and SMN, the spinal muscular atrophy protein
@ast
Coupled in vitro import of U snRNPs and SMN, the spinal muscular atrophy protein
@en
Coupled in vitro import of U snRNPs and SMN, the spinal muscular atrophy protein
@en-gb
Coupled in vitro import of U snRNPs and SMN, the spinal muscular atrophy protein
@nl
P2093
P1433
P1476
Coupled in vitro import of U snRNPs and SMN, the spinal muscular atrophy protein
@en
P2093
A Gregory Matera
Tilmann Achsel
Usha Narayanan
P304
P356
10.1016/J.MOLCEL.2004.09.024
P407
P577
2004-10-22T00:00:00Z