A Drosophila melanogaster model of spinal muscular atrophy reveals a function for SMN in striated muscle.
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Modeling spinal muscular atrophy in DrosophilaSurvival motor neuron protein regulates stem cell division, proliferation, and differentiation in DrosophilaTwo distinct arginine methyltransferases are required for biogenesis of Sm-class ribonucleoproteinsThe contribution of mouse models to understanding the pathogenesis of spinal muscular atrophyThe Cajal body and histone locus bodyIs spinal muscular atrophy a disease of the motor neurons only: pathogenesis and therapeutic implications?Homeostatic plasticity at the Drosophila neuromuscular junctionA motor function for the DEAD-box RNA helicase, Gemin3, in DrosophilaMulti-Trait GWAS and New Candidate Genes Annotation for Growth Curve Parameters in Brahman CattleDrosophila as an In Vivo Model for Human Neurodegenerative DiseaseThe neuroprotective drug riluzole acts via small conductance Ca2+-activated K+ channels to ameliorate defects in spinal muscular atrophy modelsEffects of 2,4-diaminoquinazoline derivatives on SMN expression and phenotype in a mouse model for spinal muscular atrophySMN is required for sensory-motor circuit function in Drosophila.Molecular determinants of survival motor neuron (SMN) protein cleavage by the calcium-activated protease, calpainRibonucleoprotein assembly defects correlate with spinal muscular atrophy severity and preferentially affect a subset of spliceosomal snRNPsDifferent atrophy-hypertrophy transcription pathways in muscles affected by severe and mild spinal muscular atrophy.The evolutionarily conserved RNA binding protein SMOOTH is essential for maintaining normal muscle functionConserved genes act as modifiers of invertebrate SMN loss of function defectsSpinal muscular atrophy: why do low levels of survival motor neuron protein make motor neurons sick?The secreted MSP domain of C. elegans VAPB homolog VPR-1 patterns the adult striated muscle mitochondrial reticulum via SMN-1Drosophila melanogaster in the study of human neurodegeneration.Invertebrate models of spinal muscular atrophy: insights into mechanisms and potential therapeutics.Survival motor neuron protein deficiency impairs myotube formation by altering myogenic gene expression and focal adhesion dynamics.Analysis of the fibroblast growth factor system reveals alterations in a mouse model of spinal muscular atrophyDrug discovery and development for spinal muscular atrophy: lessons from screening approaches and future challenges for clinical development.Morindone, an anthraquinone, intercalates DNA sans toxicity: a spectroscopic and molecular modeling perspective.GEMINs: potential therapeutic targets for spinal muscular atrophy?Drosophila Zpr1 (Zinc finger protein 1) is required downstream of both EGFR and FGFR signaling in tracheal subcellular lumen formationSystemic peptide-mediated oligonucleotide therapy improves long-term survival in spinal muscular atrophy.Flightless flies: Drosophila models of neuromuscular disease.Modeling spinal muscular atrophy in Drosophila links Smn to FGF signalingThe Gemin associates of survival motor neuron are required for motor function in Drosophila.Model systems of motor neuron diseases as a platform for studying pathogenic mechanisms and searching for therapeutic agents.Neurogenic and myogenic contributions to hereditary motor neuron disease.A Drosophila model of spinal muscular atrophy uncouples snRNP biogenesis functions of survival motor neuron from locomotion and viability defects.The survival motor neuron gene smn-1 interacts with the U2AF large subunit gene uaf-1 to regulate Caenorhabditis elegans lifespan and motor functions.Survival motor neuron protein in motor neurons determines synaptic integrity in spinal muscular atrophyBehavioral and electrophysiological outcomes of tissue-specific Smn knockdown in Drosophila melanogaster.Sm protein methylation is dispensable for snRNP assembly in Drosophila melanogaster.Evolution of an RNP assembly system: a minimal SMN complex facilitates formation of UsnRNPs in Drosophila melanogaster
P2860
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P2860
A Drosophila melanogaster model of spinal muscular atrophy reveals a function for SMN in striated muscle.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
A Drosophila melanogaster mode ...... on for SMN in striated muscle.
@ast
A Drosophila melanogaster mode ...... on for SMN in striated muscle.
@en
type
label
A Drosophila melanogaster mode ...... on for SMN in striated muscle.
@ast
A Drosophila melanogaster mode ...... on for SMN in striated muscle.
@en
prefLabel
A Drosophila melanogaster mode ...... on for SMN in striated muscle.
@ast
A Drosophila melanogaster mode ...... on for SMN in striated muscle.
@en
P2093
P2860
P921
P356
P1476
A Drosophila melanogaster mode ...... ion for SMN in striated muscle
@en
P2093
Graydon B Gonsalvez
Karl B Shpargel
Michael P Walker
T K Rajendra
P2860
P304
P356
10.1083/JCB.200610053
P407
P5008
P577
2007-03-01T00:00:00Z