Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair - Wikidata - wikimedia - TriplyDB

Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair

Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair

http://www.wikidata.org/entity/Q28299185

about

BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair Ubiquitin-dependent recruitment of the Bloom syndrome helicase upon replication stress is required to suppress homologous recombination The RecQ DNA helicases in DNA repair DNA resection in eukaryotes: deciding how to fix the break Human RECQ helicases: roles in DNA metabolism, mutagenesis and cancer biology DNA end resection: many nucleases make light work Reconstitution of initial steps of dsDNA break repair by the RecF pathway of E. coli DNA End Resection: Facts and Mechanisms Role of Deubiquitinating Enzymes in DNA Repair The role of RecQ helicases in non-homologous end-joining Single-molecule visualization of RecQ helicase reveals DNA melting, nucleation, and assembly are required for processive DNA unwinding.Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family RecQ helicases in DNA double strand break repair and telomere maintenance.End-resection at DNA double-strand breaks in the three domains of life An essential DNA strand-exchange activity is conserved in the divergent N-termini of BLM orthologs.Survival and growth of yeast without telomere capping by Cdc13 in the absence of Sgs1, Exo1, and Rad9.Decatenation of DNA by the S. cerevisiae Sgs1-Top3-Rmi1 and RPA complex: a mechanism for disentangling chromosomes.Epigenetic reduction of DNA repair in progression to gastrointestinal cancer MCM8-9 complex promotes resection of double-strand break ends by MRE11-RAD50-NBS1 complex Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis Cooperation of breast cancer proteins PALB2 and piccolo BRCA2 in stimulating homologous recombination Loss of RMI2 Increases Genome Instability and Causes a Bloom-Like Syndrome Mechanisms for Structural Variation in the Human Genome The MCM8-MCM9 complex promotes RAD51 recruitment at DNA damage sites to facilitate homologous recombination.Does BLM helicase unwind nucleosomal DNA?SUMO modification regulates BLM and RAD51 interaction at damaged replication forks.A helical bundle in the N-terminal domain of the BLM helicase mediates dimer and potentially hexamer formation.DNA replication arrest leads to enhanced homologous recombination and cell death in meristems of rice OsRecQl4 mutants.Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks.The Caenorhabditis elegans Werner syndrome protein functions upstream of ATR and ATM in response to DNA replication inhibition and double-strand DNA breaks.Distinct activities of exonuclease 1 and flap endonuclease 1 at telomeric g4 DNA PARP3 affects the relative contribution of homologous recombination and nonhomologous end-joining pathways.DNA end resection by Dna2-Sgs1-RPA and its stimulation by Top3-Rmi1 and Mre11-Rad50-Xrs2.Distinct roles of RECQ1 in the maintenance of genomic stability.The full-length Saccharomyces cerevisiae Sgs1 protein is a vigorous DNA helicase that preferentially unwinds holliday junctions.53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombination.Delineation of WRN helicase function with EXO1 in the replicational stress response Regulation of homologous recombination in eukaryotes.Cdk1 uncouples CtIP-dependent resection and Rad51 filament formation during M-phase double-strand break repair When transcription meets recombination: a lesson from the human RECQ protein complexes

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Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair

http://www.wikidata.org/entity/Q28299185

description

2008 nî lūn-bûn

@nan

2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

name

Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair

@ast

Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair

@en

Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair

@nl

type

label

Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair

@ast

Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair

@en

Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair

@nl

prefLabel

Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair

@ast

Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair

@en

Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair

@nl

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PNAS.0809380105

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair

@en

P2093

A Zeynep Ozsoy

http://www.w3.org/2001/XMLSchema#string

Amitabh V Nimonkar

http://www.w3.org/2001/XMLSchema#string

Jochen Genschel

http://www.w3.org/2001/XMLSchema#string

Paul Modrich

http://www.w3.org/2001/XMLSchema#string

Stephen C Kowalczykowski

http://www.w3.org/2001/XMLSchema#string

P2860

Human exonuclease I interacts with the mismatch repair protein hMSH2

Replication protein A physically interacts with the Bloom's syndrome protein and stimulates its helicase activity

Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity

Human exonuclease I is required for 5' and 3' mismatch repair

A defined human system that supports bidirectional mismatch-provoked excision

Mechanism of 5'-directed excision in human mismatch repair

Stimulation of flap endonuclease-1 by the Bloom's syndrome protein

Werner syndrome protein interacts functionally with translesion DNA polymerases

The Bloom's syndrome gene product is a 3'-5' DNA helicase

The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks

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16906-11

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scholarly article

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1240930

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10.1073/PNAS.0809380105

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44

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105

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2008-11-04T00:00:00Z

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26175448

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18971343

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2579351

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