Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neurons
about
Mood disorders in Huntington's disease: from behavior to cellular and molecular mechanismsCiliogenesis is regulated by a huntingtin-HAP1-PCM1 pathway and is altered in Huntington diseasePericentrosomal targeting of Rab6 secretory vesicles by Bicaudal-D-related protein 1 (BICDR-1) regulates neuritogenesis.pARIS-htt: an optimised expression platform to study huntingtin reveals functional domains required for vesicular traffickingNdel1 palmitoylation: a new mean to regulate cytoplasmic dynein activity.Intracellular degradation of misfolded proteins in polyglutamine neurodegenerative diseasesThe Roles of Microtubule-Based Transport at Presynaptic Nerve TerminalsThe axonal cytoskeleton: from organization to functionAxonal transport: cargo-specific mechanisms of motility and regulationHuntington's disease: the past, present, and future search for disease modifiers.PGC-1α, mitochondrial dysfunction, and Huntington's diseaseA huntingtin-mediated fast stress response halting endosomal trafficking is defective in Huntington's disease.TRIM3 regulates the motility of the kinesin motor protein KIF21BMitochondrial transport in neurons: impact on synaptic homeostasis and neurodegeneration.Huntingtin Is Required for Epithelial Polarity through RAB11A-Mediated Apical Trafficking of PAR3-aPKCAmyloid-Beta Induced Changes in Vesicular Transport of BDNF in Hippocampal NeuronsCAR-associated vesicular transport of an adenovirus in motor neuron axonsHuntingtin's function in axonal transport is conserved in Drosophila melanogasterSpatial and temporal characteristics of normal and perturbed vesicle transportAxonal Transport and Neurodegeneration: How Marine Drugs Can Be Used for the Development of TherapeuticsDeceivingly dynamic: Learning-dependent changes in stathmin and microtubulesScalable production in human cells and biochemical characterization of full-length normal and mutant huntingtinHuntingtin mediates dendritic transport of β-actin mRNA in rat neuronsThe Huntington's disease mutation impairs Huntingtin's role in the transport of NF-κB from the synapse to the nucleus.A role for huntington disease protein in dendritic RNA granulesThe regulation of autophagosome dynamics by huntingtin and HAP1 is disrupted by expression of mutant huntingtin, leading to defective cargo degradation.Axonal transport and neurodegenerative disease: can we see the elephant?Microtubule affinity-regulating kinase 2 (MARK2) turns on phosphatase and tensin homolog (PTEN)-induced kinase 1 (PINK1) at Thr-313, a mutation site in Parkinson disease: effects on mitochondrial transportIs Huntingtin Dispensable in the Adult Brain?Serine 421 regulates mutant huntingtin toxicity and clearance in mice.Mutant huntingtin impairs post-Golgi trafficking to lysosomes by delocalizing optineurin/Rab8 complex from the Golgi apparatusPathogenic huntingtin inhibits fast axonal transport by activating JNK3 and phosphorylating kinesin.Genetic and pharmacological inhibition of calcineurin corrects the BDNF transport defect in Huntington's disease.Localization of BDNF mRNA with the Huntington's disease protein in rat brain.Huntingtin coordinates the dynein-mediated dynamic positioning of endosomes and lysosomes.Molecular motor function in axonal transport in vivo probed by genetic and computational analysis in DrosophilaSubpixel colocalization reveals amyloid precursor protein-dependent kinesin-1 and dynein association with axonal vesicles.Ndel1-derived peptides modulate bidirectional transport of injected beads in the squid giant axon.Hook is an adapter that coordinates kinesin-3 and dynein cargo attachment on early endosomes.Increasing membrane cholesterol of neurons in culture recapitulates Alzheimer's disease early phenotypes.
P2860
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P2860
Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neurons
description
2008 nî lūn-bûn
@nan
2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Huntingtin phosphorylation act ...... etrograde transport in neurons
@ast
Huntingtin phosphorylation act ...... etrograde transport in neurons
@en
Huntingtin phosphorylation act ...... etrograde transport in neurons
@en-gb
Huntingtin phosphorylation act ...... etrograde transport in neurons
@nl
type
label
Huntingtin phosphorylation act ...... etrograde transport in neurons
@ast
Huntingtin phosphorylation act ...... etrograde transport in neurons
@en
Huntingtin phosphorylation act ...... etrograde transport in neurons
@en-gb
Huntingtin phosphorylation act ...... etrograde transport in neurons
@nl
prefLabel
Huntingtin phosphorylation act ...... etrograde transport in neurons
@ast
Huntingtin phosphorylation act ...... etrograde transport in neurons
@en
Huntingtin phosphorylation act ...... etrograde transport in neurons
@en-gb
Huntingtin phosphorylation act ...... etrograde transport in neurons
@nl
P2093
P2860
P50
P921
P3181
P356
P1433
P1476
Huntingtin phosphorylation act ...... etrograde transport in neurons
@en
P2093
Emilie Colin
Hélène Rangone
Xiao-Jiang Li
P2860
P304
P3181
P356
10.1038/EMBOJ.2008.133
P407
P577
2008-07-10T00:00:00Z