Phospholipase C-gamma1 interacts with conserved phosphotyrosyl residues in the linker region of Syk and is a substrate for Syk
about
The Syk tyrosine kinase suppresses malignant growth of human breast cancer cellsMolecular basis for a direct interaction between the Syk protein-tyrosine kinase and phosphoinositide 3-kinaseIdentification of two tyrosine phosphoproteins, pp70 and pp68, which interact with phospholipase Cgamma, Grb2, and Vav after B cell antigen receptor activationA novel B lymphocyte-associated adaptor protein, Bam32, regulates antigen receptor signaling downstream of phosphatidylinositol 3-kinaseActivation of the Syk tyrosine kinase is insufficient for downstream signal transduction in B lymphocytes.Inhibition of Spleen Tyrosine Kinase Potentiates Paclitaxel-Induced Cytotoxicity in Ovarian Cancer Cells by Stabilizing Microtubules.Tyrosine phosphorylation of SLP-76 is downstream of Syk following stimulation of the collagen receptor in plateletsInteraction of SLP adaptors with the SH2 domain of Tec family kinasesEvidence that phospholipase C-gamma2 interacts with SLP-76, Syk, Lyn, LAT and the Fc receptor gamma-chain after stimulation of the collagen receptor glycoprotein VI in human plateletsBLNK: molecular scaffolding through 'cis'-mediated organization of signaling proteinsSyk is required for BCR-mediated activation of p90Rsk, but not p70S6k, via a mitogen-activated protein kinase-independent pathway in B cellsRelocation of Syk protein-tyrosine kinase to the actin filament network and subsequent association with FakRegulation of mouse PECAM-1 tyrosine phosphorylation by the Src and Csk families of protein-tyrosine kinasesSLP-76 is a direct substrate of SHP-1 recruited to killer cell inhibitory receptorsDifferential intrinsic enzymatic activity of Syk and Zap-70 protein-tyrosine kinasesSyk activation and dissociation from the B-cell antigen receptor is mediated by phosphorylation of tyrosine 130Phosphorylation of Tyr342 in the linker region of Syk is critical for Fc epsilon RI signaling in mast cellsPhospholipase D2 acts as an essential adaptor protein in the activation of Syk in antigen-stimulated mast cellsFour tyrosine residues in phospholipase C-gamma 2, identified as Btk-dependent phosphorylation sites, are required for B cell antigen receptor-coupled calcium signalingThe Syk family of protein tyrosine kinases in T-cell activation and developmentTULA-2 Protein Phosphatase Suppresses Activation of Syk through the GPVI Platelet Receptor for Collagen by Dephosphorylating Tyr(P)346, a Regulatory Site of SykTec kinases mediate sustained calcium influx via site-specific tyrosine phosphorylation of the phospholipase Cgamma Src homology 2-Src homology 3 linker.Functional independence and interdependence of the Src homology domains of phospholipase C-gamma1 in B-cell receptor signal transduction.The SH3 domain of Bruton's tyrosine kinase displays altered ligand binding properties when auto-phosphorylated in vitro.Regulation of the pp72syk protein tyrosine kinase by platelet integrin alpha IIb beta 3Regulation of the helix-loop-helix proteins, E2A and Id3, by the Ras-ERK MAPK cascade.The Syk protein tyrosine kinase is essential for Fcgamma receptor signaling in macrophages and neutrophilsA unique insert in the linker domain of Syk is necessary for its function in immunoreceptor signalling.Phosphorylation of Tyr319 in ZAP-70 is required for T-cell antigen receptor-dependent phospholipase C-gamma1 and Ras activation.Mercury alters endogenous phosphorylation profiles of SYK in murine B cells.LAT is required for tyrosine phosphorylation of phospholipase cgamma2 and platelet activation by the collagen receptor GPVI.BLNK mediates Syk-dependent Btk activation.Regulation and function of syk tyrosine kinase in mast cell signaling and beyond.Rhamnus davurica leaf extract inhibits Fyn activation by antigen in mast cells for anti-allergic activity.Sensitive kinase assay linked with phosphoproteomics for identifying direct kinase substrates.Cholesterol deficiency in a mouse model of Smith-Lemli-Opitz syndrome reveals increased mast cell responsiveness.Human caspase-4 and caspase-5 regulate the one-step non-canonical inflammasome activation in monocytes.The SH3 domain of Lck modulates T-cell receptor-dependent activation of extracellular signal-regulated kinase through activation of Raf-1.Regulation of T-cell antigen receptor signalling by Syk tyrosine protein kinaseThe SYK tyrosine kinase: a crucial player in diverse biological functions.
P2860
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P2860
Phospholipase C-gamma1 interacts with conserved phosphotyrosyl residues in the linker region of Syk and is a substrate for Syk
description
1996 nî lūn-bûn
@nan
1996 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Phospholipase C-gamma1 interac ...... Syk and is a substrate for Syk
@ast
Phospholipase C-gamma1 interac ...... Syk and is a substrate for Syk
@en
Phospholipase C-gamma1 interac ...... Syk and is a substrate for Syk
@en-gb
Phospholipase C-gamma1 interac ...... Syk and is a substrate for Syk
@nl
type
label
Phospholipase C-gamma1 interac ...... Syk and is a substrate for Syk
@ast
Phospholipase C-gamma1 interac ...... Syk and is a substrate for Syk
@en
Phospholipase C-gamma1 interac ...... Syk and is a substrate for Syk
@en-gb
Phospholipase C-gamma1 interac ...... Syk and is a substrate for Syk
@nl
prefLabel
Phospholipase C-gamma1 interac ...... Syk and is a substrate for Syk
@ast
Phospholipase C-gamma1 interac ...... Syk and is a substrate for Syk
@en
Phospholipase C-gamma1 interac ...... Syk and is a substrate for Syk
@en-gb
Phospholipase C-gamma1 interac ...... Syk and is a substrate for Syk
@nl
P2093
P2860
P3181
P356
P1476
Phospholipase C-gamma1 interac ...... Syk and is a substrate for Syk
@en
P2093
K A Chandran
S P Sidorenko
P2860
P304
P3181
P356
10.1128/MCB.16.4.1305
P407
P577
1996-04-01T00:00:00Z