The hereditary renal cell carcinoma 3;8 translocation fuses FHIT to a patched-related gene, TRC8
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RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitinationThe TRC8 ubiquitin ligase is sterol regulated and interacts with lipid and protein biosynthetic pathwaysThe TRC8 hereditary kidney cancer gene suppresses growth and functions with VHL in a common pathwayRING-dependent tumor suppression and G2/M arrest induced by the TRC8 hereditary kidney cancer geneSterol-regulated degradation of Insig-1 mediated by the membrane-bound ubiquitin ligase gp78The sterol-sensing endoplasmic reticulum (ER) membrane protein TRC8 hampers ER to Golgi transport of sterol regulatory element-binding protein-2 (SREBP-2)/SREBP cleavage-activated protein and reduces SREBP-2 cleavageThe TRC8 E3 ligase ubiquitinates MHC class I molecules before dislocation from the ERRINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesisUbiquitin ligases in cholesterol metabolismRepresentational oligonucleotide microarray analysis: a high-resolution method to detect genome copy number variationCholesterol biosynthesis from lanosterol: molecular cloning, chromosomal localization, functional expression and liver-specific gene regulation of rat sterol delta8-isomerase, a cholesterogenic enzyme with multiple functionsCholesterol biosynthesis from lanosterol. Molecular cloning, tissue distribution, expression, chromosomal localization, and regulation of rat 7-dehydrocholesterol reductase, a Smith-Lemli-Opitz syndrome-related proteinIntegrated analysis of gene expression, CpG island methylation, and gene copy number in breast cancer cells by deep sequencingA comprehensive analysis of loss of heterozygosity caused by hemizygous deletions in renal cell carcinoma using a subtraction library.Tissue gene expression analysis using arrayed normalized cDNA librariesTranslocation breakpoints in FHIT and FRA3B in both homologs of chromosome 3 in an esophageal adenocarcinoma.A palindrome-driven complex rearrangement of 22q11.2 and 8q24.1 elucidated using novel technologiesAnalysis of the t(3;8) of hereditary renal cell carcinoma: a palindrome-mediated translocation.A palindrome-mediated recurrent translocation with 3:1 meiotic nondisjunction: the t(8;22)(q24.13;q11.21).Evaluating translocation gene fusions by SNP array data.Familial adult renal neoplasiaThe Unfolded Protein Response, Degradation from Endoplasmic Reticulum and CancerViral and cellular MARCH ubiquitin ligases and cancer.Renal cancer: cytogenetic and molecular genetic aspects.Familial clear cell renal cell carcinoma (FCRC): clinical features and mutation analysis of the VHL, MET, and CUL2 candidate genes.Specific haplotypes of the RET proto-oncogene are over-represented in patients with sporadic papillary thyroid carcinoma.Sterol-induced degradation of HMG CoA reductase depends on interplay of two Insigs and two ubiquitin ligases, gp78 and Trc8.Latent herpes simplex virus infection of sensory neurons alters neuronal gene expression.Endoplasmic reticulum degradation requires lumen to cytosol signaling. Transmembrane control of Hrd1p by Hrd3p.Ubiquitin ligases, critical mediators of endoplasmic reticulum-associated degradationSterols regulate processing of carbohydrate chains of wild-type SREBP cleavage-activating protein (SCAP), but not sterol-resistant mutants Y298C or D443N.Glioblastomas with copy number gains in EGFR and RNF139 show increased expressions of carbonic anhydrase genes transformed by ENO1.TRC8-dependent degradation of hepatitis C virus immature core protein regulates viral propagation and pathogenesisPorcine JAB1 significantly enhances apoptosis induced by staurosporine.The tumor suppressor gene TRC8/RNF139 is disrupted by a constitutional balanced translocation t(8;22)(q24.13;q11.21) in a young girl with dysgerminoma.Translocations in epithelial cancers.The Role of the Transmembrane RING Finger Proteins in Cellular and Organelle FunctionReciprocal translocations in breast tumor cell lines: cloning of a t(3;20) that targets the FHIT gene.TRC8 suppresses tumorigenesis through targeting heme oxygenase-1 for ubiquitination and degradation.Nuclear Pedigree Criteria for the Identification of Individuals Suspected to be at Risk of an Inherited Predisposition to Renal Cancer.
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P2860
The hereditary renal cell carcinoma 3;8 translocation fuses FHIT to a patched-related gene, TRC8
description
1998 nî lūn-bûn
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1998 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
The hereditary renal cell carc ...... o a patched-related gene, TRC8
@ast
The hereditary renal cell carc ...... o a patched-related gene, TRC8
@en
The hereditary renal cell carc ...... o a patched-related gene, TRC8
@en-gb
The hereditary renal cell carc ...... o a patched-related gene, TRC8
@nl
type
label
The hereditary renal cell carc ...... o a patched-related gene, TRC8
@ast
The hereditary renal cell carc ...... o a patched-related gene, TRC8
@en
The hereditary renal cell carc ...... o a patched-related gene, TRC8
@en-gb
The hereditary renal cell carc ...... o a patched-related gene, TRC8
@nl
prefLabel
The hereditary renal cell carc ...... o a patched-related gene, TRC8
@ast
The hereditary renal cell carc ...... o a patched-related gene, TRC8
@en
The hereditary renal cell carc ...... o a patched-related gene, TRC8
@en-gb
The hereditary renal cell carc ...... o a patched-related gene, TRC8
@nl
P2093
P2860
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P1476
The hereditary renal cell carc ...... o a patched-related gene, TRC8
@en
P2093
H A Drabkin
L J Robinson
R M Gemmill
P2860
P304
P3181
P356
10.1073/PNAS.95.16.9572
P407
P577
1998-08-04T00:00:00Z