A new orphan member of the nuclear hormone receptor superfamily that interacts with a subset of retinoic acid response elements
about
SXR, a novel steroid and xenobiotic-sensing nuclear receptorReciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CARCross-repression, a functional consequence of the physical interaction of non-liganded nuclear receptors and POU domain transcription factorsActivation of the orphan receptor RIP14 by retinoidsThe xenobiotic compound 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene is an agonist ligand for the nuclear receptor CARPhenobarbital-responsive nuclear translocation of the receptor CAR in induction of the CYP2B geneA novel orphan receptor specific for a subset of thyroid hormone-responsive elements and its interaction with the retinoid/thyroid hormone receptor subfamilyIdentification of a human nuclear receptor defines a new signaling pathway for CYP3A inductionExclusive homodimerization of the orphan receptor hepatocyte nuclear factor 4 defines a new subclass of nuclear receptorsAlternatively spliced isoforms of the human constitutive androstane receptorDiurnal difference in CAR mRNA expressionComplex effects of rexinoids on ligand dependent activation or inhibition of the xenobiotic receptor, CARAlternative splicing affects the function and tissue-specific expression of the human constitutive androstane receptorRegulation of the cytosolic sulfotransferases by nuclear receptorsModulation of xenobiotic receptors by steroidsA brief history of the discovery of PXR and CAR as xenobiotic receptorsThe repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 geneSmall heterodimer partner, an orphan nuclear receptor, augments peroxisome proliferator-activated receptor gamma transactivationInhibitory cross-talk between estrogen receptor (ER) and constitutively activated androstane receptor (CAR). CAR inhibits ER-mediated signaling pathway by squelching p160 coactivatorsDifferential transactivation by two isoforms of the orphan nuclear hormone receptor CARAMP-activated protein kinase mediates phenobarbital induction of CYP2B gene expression in hepatocytes and a newly derived human hepatoma cell lineXenobiotic induction of cytochrome P450 2B1 (CYP2B1) is mediated by the orphan nuclear receptor constitutive androstane receptor (CAR) and requires steroid co-activator 1 (SRC-1) and the transcription factor Sp1Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligandsStructural and functional similarity of amphibian constitutive androstane receptor with mammalian pregnane X receptorTransactivation Assays to Assess Canine and Rodent Pregnane X Receptor (PXR) and Constitutive Androstane Receptor (CAR) ActivationNovel functions of PXR in cardiometabolic disease.Molecular dynamics simulations of the human CAR ligand-binding domain: deciphering the molecular basis for constitutive activity.Structure and expression of the orphan nuclear receptor SHP gene.Sexually dimorphic regulation and induction of P450s by the constitutive androstane receptor (CAR).Coordinated regulation of nuclear receptor CAR by CCRP/DNAJC7, HSP70 and the ubiquitin-proteasome system.A single amino acid controls the functional switch of human constitutive androstane receptor (CAR) 1 to the xenobiotic-sensitive splicing variant CAR3.Phenobarbital Meets Phosphorylation of Nuclear ReceptorsUse of transgenic mice in UDP-glucuronosyltransferase (UGT) studiesSulfotransferase genes: regulation by nuclear receptors in response to xeno/endo-biotics.Activation of xenobiotic receptors: driving into the nucleus.The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene.Retinoid X receptor-alpha-dependent transactivation by a naturally occurring structural variant of human constitutive androstane receptor (NR1I3).Regulation of cytochrome P450 (CYP) genes by nuclear receptors.Modulation of retinoic acid sensitivity in lung cancer cells through dynamic balance of orphan receptors nur77 and COUP-TF and their heterodimerization.CAR2 displays unique ligand binding and RXRalpha heterodimerization characteristics.
P2860
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P2860
A new orphan member of the nuclear hormone receptor superfamily that interacts with a subset of retinoic acid response elements
description
1994 nî lūn-bûn
@nan
1994 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի մարտին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
A new orphan member of the nuc ...... etinoic acid response elements
@ast
A new orphan member of the nuc ...... etinoic acid response elements
@en
A new orphan member of the nuc ...... etinoic acid response elements
@en-gb
A new orphan member of the nuc ...... etinoic acid response elements
@nl
type
label
A new orphan member of the nuc ...... etinoic acid response elements
@ast
A new orphan member of the nuc ...... etinoic acid response elements
@en
A new orphan member of the nuc ...... etinoic acid response elements
@en-gb
A new orphan member of the nuc ...... etinoic acid response elements
@nl
prefLabel
A new orphan member of the nuc ...... etinoic acid response elements
@ast
A new orphan member of the nuc ...... etinoic acid response elements
@en
A new orphan member of the nuc ...... etinoic acid response elements
@en-gb
A new orphan member of the nuc ...... etinoic acid response elements
@nl
P2093
P2860
P3181
P356
P1476
A new orphan member of the nuc ...... etinoic acid response elements
@en
P2093
P2860
P304
P3181
P356
10.1128/MCB.14.3.1544
P407
P577
1994-03-01T00:00:00Z