Phenobarbital-responsive nuclear translocation of the receptor CAR in induction of the CYP2B gene
about
Regional induction of CYP1A1 in rat liver following treatment with mixtures of PCB 126 and PCB 153Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CARThe xenobiotic compound 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene is an agonist ligand for the nuclear receptor CARAlternatively spliced isoforms of the human constitutive androstane receptorInduction of bilirubin clearance by the constitutive androstane receptor (CAR)Complex effects of rexinoids on ligand dependent activation or inhibition of the xenobiotic receptor, CARAlternative splicing affects the function and tissue-specific expression of the human constitutive androstane receptorEndotoxin leads to rapid subcellular re-localization of hepatic RXRalpha: A novel mechanism for reduced hepatic gene expression in inflammationThe evolution of drug-activated nuclear receptors: one ancestral gene diverged into two xenosensor genes in mammalsPhenobarbital induces alterations in the proteome of hepatocytes and mesenchymal cells of rat liversPhenobarbital mediates an epigenetic switch at the constitutive androstane receptor (CAR) target gene Cyp2b10 in the liver of B6C3F1 miceInsights into CYP2B6-mediated drug-drug interactionsActivation of orphan nuclear constitutive androstane receptor requires subnuclear targeting by peroxisome proliferator-activated receptor gamma coactivator-1 alpha. A possible link between xenobiotic response and nutritional stateIdentification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genesInhibitory cross-talk between estrogen receptor (ER) and constitutively activated androstane receptor (CAR). CAR inhibits ER-mediated signaling pathway by squelching p160 coactivatorsPhenobarbital confers its diverse effects by activating the orphan nuclear receptor carPhenobarbital indirectly activates the constitutive active androstane receptor (CAR) by inhibition of epidermal growth factor receptor signalingAMP-activated protein kinase mediates phenobarbital induction of CYP2B gene expression in hepatocytes and a newly derived human hepatoma cell lineXenobiotic induction of cytochrome P450 2B1 (CYP2B1) is mediated by the orphan nuclear receptor constitutive androstane receptor (CAR) and requires steroid co-activator 1 (SRC-1) and the transcription factor Sp1Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligandsThe roles of co-chaperone CCRP/DNAJC7 in Cyp2b10 gene activation and steatosis development in mouse liversPossible involvement of oxidative stress in fenofibrate-induced hepatocarcinogenesis in ratsABC transporter function and regulation at the blood-spinal cord barrierInduction of nuclear translocation of constitutive androstane receptor by peroxisome proliferator-activated receptor alpha synthetic ligands in mouse liverOverexpression of the Rho-guanine nucleotide exchange factor ECT2 inhibits nuclear translocation of nuclear receptor CAR in the mouse liverPregnane X receptor and natural products: beyond drug-drug interactionsRegulation of Drug Disposition Gene Expression in Pregnant Mice with Car Receptor ActivationCloning, functional expression, and characterization of CYP709C1, the first sub-terminal hydroxylase of long chain fatty acid in plants. Induction by chemicals and methyl jasmonate.Coordinated regulation of nuclear receptor CAR by CCRP/DNAJC7, HSP70 and the ubiquitin-proteasome system.A single amino acid controls the functional switch of human constitutive androstane receptor (CAR) 1 to the xenobiotic-sensitive splicing variant CAR3.Phenobarbital Meets Phosphorylation of Nuclear ReceptorsProteasomal interaction as a critical activity modulator of the human constitutive androstane receptor.Transcription coactivator PBP/MED1-deficient hepatocytes are not susceptible to diethylnitrosamine-induced hepatocarcinogenesis in the mouse.Tissue-specific chromatin structure of the phenobarbital-responsive unit and proximal promoter of CYP2B1/2 and modulation by phenobarbital.Dietary flavonoids activate the constitutive androstane receptor (CAR).Sulfotransferase genes: regulation by nuclear receptors in response to xeno/endo-biotics.Activation of xenobiotic receptors: driving into the nucleus.Retinoid X receptor-alpha-dependent transactivation by a naturally occurring structural variant of human constitutive androstane receptor (NR1I3).Nuclear receptor CAR (NR1I3) is essential for DDC-induced liver injury and oval cell proliferation in mouse liver.Phenobarbital and propiconazole toxicogenomic profiles in mice show major similarities consistent with the key role that constitutive androstane receptor (CAR) activation plays in their mode of action
P2860
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P2860
Phenobarbital-responsive nuclear translocation of the receptor CAR in induction of the CYP2B gene
description
1999 nî lūn-bûn
@nan
1999 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Phenobarbital-responsive nucle ...... in induction of the CYP2B gene
@ast
Phenobarbital-responsive nucle ...... in induction of the CYP2B gene
@en
Phenobarbital-responsive nucle ...... in induction of the CYP2B gene
@nl
type
label
Phenobarbital-responsive nucle ...... in induction of the CYP2B gene
@ast
Phenobarbital-responsive nucle ...... in induction of the CYP2B gene
@en
Phenobarbital-responsive nucle ...... in induction of the CYP2B gene
@nl
prefLabel
Phenobarbital-responsive nucle ...... in induction of the CYP2B gene
@ast
Phenobarbital-responsive nucle ...... in induction of the CYP2B gene
@en
Phenobarbital-responsive nucle ...... in induction of the CYP2B gene
@nl
P2093
P2860
P3181
P356
P1476
Phenobarbital-responsive nucle ...... in induction of the CYP2B gene
@en
P2093
P2860
P304
P3181
P356
10.1128/MCB.19.9.6318
P407
P577
1999-09-01T00:00:00Z