Involvement of the homeodomain-containing transcription factor PDX-1 in islet amyloid polypeptide gene transcription
about
Factors involved in the duodenal expression of the human calbindin-D9k geneConserved sequences in a tissue-specific regulatory region of the pdx-1 gene mediate transcription in Pancreatic beta cells: role for hepatocyte nuclear factor 3 beta and Pax6Members of the large Maf transcription family regulate insulin gene transcription in islet beta cellsA feat of metabolic proportions: Pdx1 orchestrates islet development and function in the maintenance of glucose homeostasis.Glucose-dependent translocation of insulin promoter factor-1 (IPF-1) between the nuclear periphery and the nucleoplasm of single MIN6 beta-cells.Gene expression in pancreatic adenocarcinoma.The hypofunctional effect of P335L single nucleotide polymorphism on SSTR5 function.PDX-1 is a therapeutic target for pancreatic cancer, insulinoma and islet neoplasia using a novel RNA interference platformC-Abl inhibitor imatinib enhances insulin production by β cells: c-Abl negatively regulates insulin production via interfering with the expression of NKx2.2 and GLUT-2.Karyopherins in nuclear transport of homeodomain proteins during development.Metformin Restrains Pancreatic Duodenal Homeobox-1 (PDX-1) Function by Inhibiting ERK Signaling in Pancreatic Ductal Adenocarcinoma.Thioredoxin-interacting protein promotes islet amyloid polypeptide expression through miR-124a and FoxA2.Defining the cancer master switch.In vivo conversion of adult α-cells into β-like cells: a new research avenue in the context of type 1 diabetes.The endocrine pancreas: insights into development, differentiation, and diabetes.Characterization of pancreatic transcription factor Pdx-1 binding sites using promoter microarray and serial analysis of chromatin occupancy.Suppression of transcription factor PDX-1/IPF1/STF-1/IDX-1 causes no decrease in insulin mRNA in MIN6 cells.The homeodomain of PDX-1 mediates multiple protein-protein interactions in the formation of a transcriptional activation complex on the insulin promoter.Differential expression of the insulin gene transcriptional repressor CCAAT/enhancer-binding protein beta and transactivator islet duodenum homeobox-1 in rat pancreatic beta cells during the development of diabetes mellitus.Amino acid 1-209 is essential for PDX-1-mediated repression of human CMV IE promoter activity.beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes.Glucose and forskolin regulate IAPP gene expression through different signal transduction pathways.Identification of a novel PDX-1 binding site in the human insulin gene enhancer.Suppression of the pancreatic duodenal homeodomain transcription factor-1 (Pdx-1) promoter by sterol regulatory element-binding protein-1c (SREBP-1c).Upstream stimulatory factor regulates Pdx-1 gene expression in differentiated pancreatic beta-cells.Pdx-1 is required for activation in vivo from a duodenum-specific enhancer.Transcription factor occupancy of the insulin gene in vivo. Evidence for direct regulation by Nkx2.2.Reduced PDX-1 expression impairs islet response to insulin resistance and worsens glucose homeostasis.Pancreatic beta cell-specific transcription of the pdx-1 gene. The role of conserved upstream control regions and their hepatic nuclear factor 3beta sites.
P2860
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P2860
Involvement of the homeodomain-containing transcription factor PDX-1 in islet amyloid polypeptide gene transcription
description
1996 nî lūn-bûn
@nan
1996 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Involvement of the homeodomain ...... polypeptide gene transcription
@ast
Involvement of the homeodomain ...... polypeptide gene transcription
@en
Involvement of the homeodomain ...... polypeptide gene transcription
@en-gb
Involvement of the homeodomain ...... polypeptide gene transcription
@nl
type
label
Involvement of the homeodomain ...... polypeptide gene transcription
@ast
Involvement of the homeodomain ...... polypeptide gene transcription
@en
Involvement of the homeodomain ...... polypeptide gene transcription
@en-gb
Involvement of the homeodomain ...... polypeptide gene transcription
@nl
prefLabel
Involvement of the homeodomain ...... polypeptide gene transcription
@ast
Involvement of the homeodomain ...... polypeptide gene transcription
@en
Involvement of the homeodomain ...... polypeptide gene transcription
@en-gb
Involvement of the homeodomain ...... polypeptide gene transcription
@nl
P2093
P356
P1476
Involvement of the homeodomain ...... polypeptide gene transcription
@en
P2093
J i Miyazaki
T Matsuoka
Y Fujitani
Y Kajimoto
Y Yamasaki
P304
P356
10.1006/BBRC.1996.1875
P407
P577
1996-12-24T00:00:00Z