DJ-1 transcriptionally up-regulates the human tyrosine hydroxylase by inhibiting the sumoylation of pyrimidine tract-binding protein-associated splicing factor - Wikidata - wikimedia - TriplyDB

DJ-1 transcriptionally up-regulates the human tyrosine hydroxylase by inhibiting the sumoylation of pyrimidine tract-binding protein-associated splicing factor

DJ-1 transcriptionally up-regulates the human tyrosine hydroxylase by inhibiting the sumoylation of pyrimidine tract-binding protein-associated splicing factor

http://www.wikidata.org/entity/Q24338249

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Oxidative status of DJ-1-dependent activation of dopamine synthesis through interaction of tyrosine hydroxylase and 4-dihydroxy-L-phenylalanine (L-DOPA) decarboxylase with DJ-1 DJ-1 induces thioredoxin 1 expression through the Nrf2 pathway RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways Identification of key uric acid synthesis pathway in a unique mutant silkworm Bombyx mori model of Parkinson's disease Park7 expression influences myotube size and myosin expression in muscle Structural Impact of Three Parkinsonism-Associated Missense Mutations on Human DJ-1 † , ‡Formation of a Stabilized Cysteine Sulfinic Acid Is Critical for the Mitochondrial Function of the Parkinsonism Protein DJ-1 Stereospecific mechanism of DJ-1 glyoxalases inferred from their hemithioacetal-containing crystal structures Cross Talk between Two Antioxidant Systems, Thioredoxin and DJ-1: Consequences for Cancer DEGAS: de novo discovery of dysregulated pathways in human diseases DJ-1, an oncogene and causative gene for familial Parkinson's disease, is essential for SV40 transformation in mouse fibroblasts through up-regulation of c-Myc DJ-1-dependent regulation of oxidative stress in the retinal pigment epithelium (RPE)Absence of dopaminergic neuronal degeneration and oxidative damage in aged DJ-1-deficient mice.DJ-1 modulates alpha-synuclein aggregation state in a cellular model of oxidative stress: relevance for Parkinson's disease and involvement of HSP70.Tyrosine hydroxylase gene: another piece of the genetic puzzle of Parkinson's disease Identification of glutathione (GSH)-independent glyoxalase III from Schizosaccharomyces pombe.Mechanisms of Parkinson's disease-related proteins in mediating secondary brain damage after cerebral ischemia.DJ-1 deficient mice demonstrate similar vulnerability to pathogenic Ala53Thr human alpha-syn toxicity.Pretreatment with Sodium Phenylbutyrate Alleviates Cerebral Ischemia/Reperfusion Injury by Upregulating DJ-1 Protein.Immunostaining of oxidized DJ-1 in human and mouse brains Insulin-like growth factor-I activates extracellularly regulated kinase to regulate the p450 side-chain cleavage insulin-like response element in granulosa cells Convergence of miRNA expression profiling, α-synuclein interacton and GWAS in Parkinson's disease.Reactive oxygen species-mediated DJ-1 monomerization modulates intracellular trafficking involving karyopherin β2 Engineered disulfide bonds restore chaperone-like function of DJ-1 mutants linked to familial Parkinson's disease.The oxidation states of DJ-1 dictate the cell fate in response to oxidative stress triggered by 4-hpr: autophagy or apoptosis?Decreased DJ-1 leads to impaired Nrf2-regulated antioxidant defense and increased UV-A-induced apoptosis in corneal endothelial cells.Multiple coregulatory control of tyrosine hydroxylase gene transcription Transcriptional activation of low-density lipoprotein receptor gene by DJ-1 and effect of DJ-1 on cholesterol homeostasis Age-related changes in the retinal pigment epithelium (RPE).Human DJ-1-specific transcriptional activation of tyrosine hydroxylase gene Biosignatures for Parkinson's disease and atypical parkinsonian disorders patients.The DBHS proteins SFPQ, NONO and PSPC1: a multipurpose molecular scaffold Monomer DJ-1 and its N-terminal sequence are necessary for mitochondrial localization of DJ-1 mutants.Identification of the recognition sequence and target proteins for DJ-1 protease.The role of cysteine oxidation in DJ-1 function and dysfunction.Transcriptional activation of the cholecystokinin gene by DJ-1 through interaction of DJ-1 with RREB1 and the effect of DJ-1 on the cholecystokinin level in mice.Neuroprotective effect of a new DJ-1-binding compound against neurodegeneration in Parkinson's disease and stroke model rats A DJ-1 Based Peptide Attenuates Dopaminergic Degeneration in Mice Models of Parkinson's Disease via Enhancing Nrf2.A Physical Interaction between the Dopamine Transporter and DJ-1 Facilitates Increased Dopamine Reuptake PSF: nuclear busy-body or nuclear facilitator?

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DJ-1 transcriptionally up-regulates the human tyrosine hydroxylase by inhibiting the sumoylation of pyrimidine tract-binding protein-associated splicing factor

http://www.wikidata.org/entity/Q24338249

description

2006 nî lūn-bûn

@nan

2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2006年の論文

@ja

2006年論文

@yue

2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

name

DJ-1 transcriptionally up-regu ...... ein-associated splicing factor

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DJ-1 transcriptionally up-regu ...... ein-associated splicing factor

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DJ-1 transcriptionally up-regu ...... ein-associated splicing factor

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DJ-1 transcriptionally up-regu ...... ein-associated splicing factor

@nl

type

label

DJ-1 transcriptionally up-regu ...... ein-associated splicing factor

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DJ-1 transcriptionally up-regu ...... ein-associated splicing factor

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DJ-1 transcriptionally up-regu ...... ein-associated splicing factor

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DJ-1 transcriptionally up-regu ...... ein-associated splicing factor

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prefLabel

DJ-1 transcriptionally up-regu ...... ein-associated splicing factor

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DJ-1 transcriptionally up-regu ...... ein-associated splicing factor

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DJ-1 transcriptionally up-regu ...... ein-associated splicing factor

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DJ-1 transcriptionally up-regu ...... ein-associated splicing factor

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P1433

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P3181

P356

P1433

Journal of Biological Chemistry

P1476

DJ-1 transcriptionally up-regu ...... ein-associated splicing factor

@en

P2093

Changiz Geula

http://www.w3.org/2001/XMLSchema#string

Christina Y Kim

http://www.w3.org/2001/XMLSchema#string

Douglas R Porter

http://www.w3.org/2001/XMLSchema#string

Emmanuel N Pothos

http://www.w3.org/2001/XMLSchema#string

Jin Xu

http://www.w3.org/2001/XMLSchema#string

Nan Zhong

http://www.w3.org/2001/XMLSchema#string

Patrizia Rizzu

http://www.w3.org/2001/XMLSchema#string

P2860

DJ-1 is a redox-dependent molecular chaperone that inhibits alpha-synuclein aggregate formation

PSF is a novel corepressor that mediates its effect through Sin3A and the DNA binding domain of nuclear hormone receptors

DJ-1 positively regulates the androgen receptor by impairing the binding of PIASx alpha to the receptor

The Parkinson's disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis

Down regulation of DJ-1 enhances cell death by oxidative stress, ER stress, and proteasome inhibition

Interaction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell death

DJ-1 has a role in antioxidative stress to prevent cell death

Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism

Histone sumoylation is associated with transcriptional repression

Sensitivity to oxidative stress in DJ-1-deficient dopamine neurons: an ES- derived cell model of primary Parkinsonism

P304

20940-8

http://www.w3.org/2001/XMLSchema#string

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scholarly article

P3181

2284141

http://www.w3.org/2001/XMLSchema#string

P356

10.1074/JBC.M601935200

http://www.w3.org/2001/XMLSchema#string

P407

P433

30

http://www.w3.org/2001/XMLSchema#string

P478

281

http://www.w3.org/2001/XMLSchema#string

P50

Ferdinando Squitieri

P577

2006-07-28T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

16731528

http://www.w3.org/2001/XMLSchema#string

P921

positive regulation of L-dopa biosynthetic process

Parkinsonism associated deglycase

Splicing factor proline and glutamine rich

negative regulation of SUMO transferase activity

Histone deacetylase 1