MEKK2 associates with the adapter protein Lad/RIBP and regulates the MEK5-BMK1/ERK5 pathway - Wikidata - wikimedia - TriplyDB

MEKK2 associates with the adapter protein Lad/RIBP and regulates the MEK5-BMK1/ERK5 pathway

MEKK2 associates with the adapter protein Lad/RIBP and regulates the MEK5-BMK1/ERK5 pathway

http://www.wikidata.org/entity/Q28143630

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Structure function analysis of SH2D2A isoforms expressed in T cells reveals a crucial role for the proline rich region encoded by SH2D2A exon 7 An analysis of the phosphorylation and activation of extracellular-signal-regulated protein kinase 5 (ERK5) by mitogen-activated protein kinase kinase 5 (MKK5) in vitro Mip1, an MEKK2-interacting protein, controls MEKK2 dimerization and activation.Role of MEKK2-MEK5 in the regulation of TNF-alpha gene expression and MEKK2-MKK7 in the activation of c-Jun N-terminal kinase in mast cells Knockout of ERK5 causes multiple defects in placental and embryonic development Targeting MAPK Signaling in Age-Related Macular Degeneration MEK5/ERK5 pathway: the first fifteen years ERK5 Mediated Signalling in Diabetic Retinopathy Interaction codes within the family of mammalian Phox and Bem1p domain-containing proteins Differential role of MEK5alpha and MEK5beta in BMK1/ERK5 activation WNK1 activates ERK5 by an MEKK2/3-dependent mechanism WNK1: analysis of protein kinase structure, downstream targets, and potential roles in hypertension Targeted deletion of mek5 causes early embryonic death and defects in the extracellular signal-regulated kinase 5/myocyte enhancer factor 2 cell survival pathway ERK5 MAPK regulates embryonic angiogenesis and acts as a hypoxia-sensitive repressor of vascular endothelial growth factor expression Calcium regulation of EGF-induced ERK5 activation: role of Lad1-MEKK2 interaction.G alpha(q) acts as an adaptor protein in protein kinase C zeta (PKCzeta)-mediated ERK5 activation by G protein-coupled receptors (GPCR).MEK and the inhibitors: from bench to bedside.Breast tumor kinase and extracellular signal-regulated kinase 5 mediate Met receptor signaling to cell migration in breast cancer cells.Development and validation of a high-throughput intrinsic ATPase activity assay for the discovery of MEKK2 inhibitors.Cyclic AMP selectively uncouples mitogen-activated protein kinase cascades from activating signals Modulation of protein kinase signaling cascades by palytoxin.MEK kinase 2 and the adaptor protein Lad regulate extracellular signal-regulated kinase 5 activation by epidermal growth factor via Src Reduced MCMV Δm157 viral clearance in the absence of TSAd.MAPK pathways in radiation responses.Neuronal apoptosis induced by selective inhibition of Rac GTPase versus global suppression of Rho family GTPases is mediated by alterations in distinct mitogen-activated protein kinase signaling cascades.Restoration of miR17/20a in solid tumor cells enhances the natural killer cell antitumor activity by targeting Mekk2.Wiring diagrams of MAPK regulation by MEKK1, 2, and 3.A transcription function for the T cell-specific adapter (TSAd) protein in T cells: critical role of the TSAd Src homology 2 domain.Impaired T cell death and lupus-like autoimmunity in T cell-specific adapter protein-deficient mice MAPK signalling: ERK5 versus ERK1/2.G protein regulation of MAPK networks.Role of mitogen-activated protein kinase kinase kinases in signal integration.Extracellular signal regulated kinase 5 mediates signals triggered by the novel tumor promoter palytoxin Resveratrol mitigates lipopolysaccharide-mediated acute inflammation in rats by inhibiting the TLR4/NF-κBp65/MAPKs signaling cascade.Involvement of mixed lineage kinase 3 in cancer.The role of ERK5 in endothelial cell function.Stat3 upregulates MEK5 expression in human breast cancer cells.Statin regulated ERK5 stimulates tight junction formation and reduces permeability in human cardiac endothelial cells.Oncogenic signaling of MEK5-ERK5.An alternative mode of CD43 signal transduction activates pro-survival pathways of T lymphocytes.

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P2860

MEKK2 associates with the adapter protein Lad/RIBP and regulates the MEK5-BMK1/ERK5 pathway

http://www.wikidata.org/entity/Q28143630

description

2001 nî lūn-bûn

@nan

2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2001年の論文

@ja

2001年論文

@yue

2001年論文

@zh-hant

2001年論文

@zh-hk

2001年論文

@zh-mo

2001年論文

@zh-tw

2001年论文

@wuu

name

MEKK2 associates with the adap ...... tes the MEK5-BMK1/ERK5 pathway

@ast

MEKK2 associates with the adap ...... tes the MEK5-BMK1/ERK5 pathway

@en

MEKK2 associates with the adap ...... tes the MEK5-BMK1/ERK5 pathway

@nl

type

label

MEKK2 associates with the adap ...... tes the MEK5-BMK1/ERK5 pathway

@ast

MEKK2 associates with the adap ...... tes the MEK5-BMK1/ERK5 pathway

@en

MEKK2 associates with the adap ...... tes the MEK5-BMK1/ERK5 pathway

@nl

prefLabel

MEKK2 associates with the adap ...... tes the MEK5-BMK1/ERK5 pathway

@ast

MEKK2 associates with the adap ...... tes the MEK5-BMK1/ERK5 pathway

@en

MEKK2 associates with the adap ...... tes the MEK5-BMK1/ERK5 pathway

@nl

P1433

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P1433

Journal of Biological Chemistry

P1476

MEKK2 associates with the adap ...... tes the MEK5-BMK1/ERK5 pathway

@en

P2093

B C Schaefer

http://www.w3.org/2001/XMLSchema#string

E W Gelfand

http://www.w3.org/2001/XMLSchema#string

G L Johnson

http://www.w3.org/2001/XMLSchema#string

K Kesavan

http://www.w3.org/2001/XMLSchema#string

M Ware

http://www.w3.org/2001/XMLSchema#string

N L Johnson

http://www.w3.org/2001/XMLSchema#string

T P Garrington

http://www.w3.org/2001/XMLSchema#string

W Sun

http://www.w3.org/2001/XMLSchema#string

P2860

JNKK1 organizes a MAP kinase module through specific and sequential interactions with upstream and downstream components mediated by its amino-terminal extension

Regulation of the MEF2 family of transcription factors by p38

Targeting of p38 mitogen-activated protein kinases to MEF2 transcription factors

MP1: a MEK binding partner that enhances enzymatic activation of the MAP kinase cascade

Components of a new human protein kinase signal transduction pathway

Regulatory role of MEF2D in serum induction of the c-jun promoter

Primary structure of BMK1: a new mammalian map kinase

Molecular cloning of mitogen-activated protein/ERK kinase kinases (MEKK) 2 and 3. Regulation of sequential phosphorylation pathways involving mitogen-activated protein kinase and c-Jun kinase

Characterization of the structure and function of a novel MAP kinase kinase (MKK6)

MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42

P304

5093-100

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P31

scholarly article

P3181

549041

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P356

10.1074/JBC.M003719200

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P433

7

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P478

276

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2001-02-16T00:00:00Z

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11073940

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