A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells - Wikidata - wikimedia - TriplyDB

A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells

A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells

http://www.wikidata.org/entity/Q27684407

about

Smart nanosystems: Bio-inspired technologies that interact with the host environment PDBe: improved accessibility of macromolecular structure data from PDB and EMDB Enhancement of MHC-I antigen presentation via architectural control of pH-responsive, endosomolytic polymer nanoparticles.Epstein-Barr virus and multiple sclerosis: potential opportunities for immunotherapy Current status and perspectives of patient-derived xenograft models in cancer research.Impact of Conditional miRNA126 Overexpression on Apoptosis-Resistant Endothelial Cell Production.Locating Herpesvirus Bcl-2 Homologs in the Specificity Landscape of Anti-Apoptotic Bcl-2 Proteins.Selective peptide inhibitors of antiapoptotic cellular and viral Bcl-2 proteins lead to cytochrome c release during latent Kaposi's sarcoma-associated herpesvirus infection.A Viral microRNA Cluster Regulates the Expression of PTEN, p27 and of a bcl-2 Homolog Computational design and experimental verification of a symmetric protein homodimer.Rosetta:MSF: a modular framework for multi-state computational protein design.Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer.The Bcl-2 family: structures, interactions and targets for drug discovery.Engineering CAR-T cells: Design concepts.Algorithms for protein design.Designing helical peptide inhibitors of protein-protein interactions Deep sequencing methods for protein engineering and design.Tuning DNA binding affinity and cleavage specificity of an engineered gene-targeting nuclease via surface display, flow cytometry and cellular analyses.Structural basis of apoptosis inhibition by the fowlpox virus protein FPV039.Rational design of TNFα binding proteins based on the de novo designed protein DS119.AbDesign: An algorithm for combinatorial backbone design guided by natural conformations and sequences.The Bcl-2 Family in Host-Virus Interactions.GFP-complementation assay to detect functional CPP and protein delivery into living cells.Massively parallel de novo protein design for targeted therapeutics.Mammalian display screening of diverse cystine-dense peptides for difficult to drug targets.Creation of artificial protein-protein interactions using α-helices as interfaces.High-throughput characterization of protein-protein interactions by reprogramming yeast mating.PixelDB: Protein-peptide complexes annotated with structural conservation of the peptide binding mode.Enzyme-Cleavable Polymeric Micelles for the Intracellular Delivery of Proapoptotic Peptides.The Complex Interplay between Chronic Inflammation, the Microbiome, and Cancer: Understanding Disease Progression and What We Can Do to Prevent It.Recent developments in intracellular protein delivery.Engineering altered protein-DNA recognition specificity.Protein design: from computer models to artificial intelligence coiled-coil peptides as scaffolds for disrupting protein-protein interactions Designed for life: biocompatible de novo designed proteins and components

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A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells

http://www.wikidata.org/entity/Q27684407

description

2014 nî lūn-bûn

@nan

2014 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի հունիսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

A Computationally Designed Inh ...... es Apoptosis in Infected Cells

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A Computationally Designed Inh ...... es Apoptosis in Infected Cells

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A Computationally Designed Inh ...... es Apoptosis in Infected Cells

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A Computationally Designed Inh ...... es Apoptosis in Infected Cells

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A Computationally Designed Inh ...... es Apoptosis in Infected Cells

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A Computationally Designed Inh ...... es Apoptosis in Infected Cells

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A Computationally Designed Inh ...... es Apoptosis in Infected Cells

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A Computationally Designed Inh ...... es Apoptosis in Infected Cells

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J.CELL.2014.04.034

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A Computationally Designed Inh ...... es Apoptosis in Infected Cells

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Anthony J Convertine

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Barry L Stoddard

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Betty W Shen

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Bruno E Correia

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Daciana Margineantu

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David M Hockenbery

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Garrett Booth

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Geoffrey Y Berguig

http://www.w3.org/2001/XMLSchema#string

Patrick S Stayton

http://www.w3.org/2001/XMLSchema#string

Shani Frayo

http://www.w3.org/2001/XMLSchema#string

P2860

An Epstein-Barr virus anti-apoptotic protein constitutively expressed in transformed cells and implicated in burkitt lymphomagenesis: the Wp/BHRF1 link

Design of a Novel Globular Protein Fold with Atomic-Level Accuracy

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

Electrostatics of nanosystems: application to microtubules and the ribosome

Structural basis for recognition by an in vitro evolved affibody

Epstein-Barr virus provides a new paradigm: a requirement for the immediate inhibition of apoptosis.

Conformational Changes in Bcl-2 Pro-survival Proteins Determine Their Capacity to Bind Ligands

Acidianus filamentous virus 1 coat proteins display a helical fold spanning the filamentous archaeal viruses lineage

Mcl-1-Bim complexes accommodate surprising point mutations via minor structural changes

Determinants of BH3 Binding Specificity for Mcl-1 versus Bcl-xL

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1644-56

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10.1016/J.CELL.2014.04.034

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7

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263318199

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24949974

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apoptotic process

computational biology

Epstein–Barr virus

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4079535

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