Structure determination of the three disulfide bond isomers of alpha-conotoxin GI: a model for the role of disulfide bonds in structural stability
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Solution structure of alpha-conotoxin SISolution conformation of alpha-conotoxin EI, a neuromuscular toxin specific for the alpha 1/delta subunit interface of torpedo nicotinic acetylcholine receptorA new level of conotoxin diversity, a non-native disulfide bond connectivity in alpha-conotoxin AuIB reduces structural definition but increases biological activityNMR spatial structure of alpha-conotoxin ImI reveals a common scaffold in snail and snake toxins recognizing neuronal nicotinic acetylcholine receptorsOmega-conotoxin CVID inhibits a pharmacologically distinct voltage-sensitive calcium channel associated with transmitter release from preganglionic nerve terminalsProtein Folding Determinants: Structural Features Determining Alternative Disulfide Pairing in α- and χ/λ-Conotoxins † , ‡Structure of α-conotoxin BuIA: influences of disulfide connectivity on structural dynamicsDistinct Disulfide Isomers of μ-Conotoxins KIIIA and KIIIB Block Voltage-Gated Sodium ChannelsCharacterization of a Novel -Conotoxin from Conus textile That Selectively Targets 6/ 3 2 3 Nicotinic Acetylcholine ReceptorsA novel 4/7-conotoxin LvIA from Conus lividus that selectively blocks 3 2 vs. 6/ 3 2 3 nicotinic acetylcholine receptorsNovel omega-conotoxins from Conus catus discriminate among neuronal calcium channel subtypeslambda-conotoxins, a new family of conotoxins with unique disulfide pattern and protein folding. Isolation and characterization from the venom of Conus marmoreus.Structures of muO-conotoxins from Conus marmoreus. I nhibitors of tetrodotoxin (TTX)-sensitive and TTX-resistant sodium channels in mammalian sensory neurons.Snake venom alpha-neurotoxins and other 'three-finger' proteins.Conotoxins targeting nicotinic acetylcholine receptors: an overviewAtypical alpha-conotoxin LtIA from Conus litteratus targets a novel microsite of the alpha3beta2 nicotinic receptor.Oxidative folding and preparation of α-conotoxins for use in high-throughput structure-activity relationship studies.Synthesis and activity of thioether-containing analogues of the complement inhibitor compstatin.Structure-activity relationships of alpha-conotoxins targeting neuronal nicotinic acetylcholine receptors.Modulation of conotoxin structure and function is achieved through a multienzyme complex in the venom glands of cone snails.Optimal cleavage and oxidative folding of α-conotoxin TxIB as a therapeutic candidate peptideScanning mutagenesis of alpha-conotoxin Vc1.1 reveals residues crucial for activity at the alpha9alpha10 nicotinic acetylcholine receptorSynthetic α-conotoxin mutants as probes for studying nicotinic acetylcholine receptors and in the development of novel drug leads.Therapeutic potential of conopeptides.Ion Mobility-Mass Spectrometry as a Tool for the Structural Characterization of Peptides Bearing Intramolecular Disulfide Bond(s).Influence of disulfide connectivity on structure and bioactivity of α-conotoxin TxIA.αO-Conotoxin GeXIVA disulfide bond isomers exhibit differential sensitivity for various nicotinic acetylcholine receptors but retain potency and selectivity for the human α9α10 subtype.Variants of ribonuclease inhibitor that resist oxidation.Solution conformation of alpha-conotoxin GIC, a novel potent antagonist of alpha3beta2 nicotinic acetylcholine receptors.Solid-phase synthesis and biological activity of a thioether analogue of conotoxin G1.Inhibition of the norepinephrine transporter by the venom peptide chi-MrIA. Site of action, Na+ dependence, and structure-activity relationship.Inhibition of neuronal nicotinic acetylcholine receptor subtypes by alpha-Conotoxin GID and analogues.Molecular Engineering of Conus Peptides as Therapeutic Leads.Alpha-selenoconotoxins, a new class of potent alpha7 neuronal nicotinic receptor antagonists.1,2,3-Triazole Rings as a Disulfide Bond Mimetic in Chimeric AGRP-Melanocortin Peptides: Design, Synthesis, and Functional Characterization.Scrambling of Disulfide Bond Scaffolds in neurotoxin AuIB: A Molecular Dynamics Simulation Study.Diaminodiacid-based solid-phase synthesis of peptide disulfide bond mimics.Stabilization of the cysteine-rich conotoxin MrIA by using a 1,2,3-triazole as a disulfide bond mimetic.Pathway Editing Targets for Thiamine Biofortification in Rice GrainsPrediction of disulfide dihedral angles using chemical shifts
P2860
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P2860
Structure determination of the three disulfide bond isomers of alpha-conotoxin GI: a model for the role of disulfide bonds in structural stability
description
1998 nî lūn-bûn
@nan
1998 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Structure determination of the ...... bonds in structural stability
@ast
Structure determination of the ...... bonds in structural stability
@en
Structure determination of the ...... bonds in structural stability
@nl
type
label
Structure determination of the ...... bonds in structural stability
@ast
Structure determination of the ...... bonds in structural stability
@en
Structure determination of the ...... bonds in structural stability
@nl
prefLabel
Structure determination of the ...... bonds in structural stability
@ast
Structure determination of the ...... bonds in structural stability
@en
Structure determination of the ...... bonds in structural stability
@nl
P2093
P356
P1476
Structure determination of the ...... bonds in structural stability
@en
P2093
J Gehrmann
P F Alewood
P304
P356
10.1006/JMBI.1998.1701
P407
P577
1998-05-01T00:00:00Z