Structures of muO-conotoxins from Conus marmoreus. I nhibitors of tetrodotoxin (TTX)-sensitive and TTX-resistant sodium channels in mammalian sensory neurons.
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Manipulating neuronal circuits with endogenous and recombinant cell-surface tethered modulatorsThe hitchhiker's guide to the voltage-gated sodium channel galaxyConotoxins That Could Provide Analgesia through Voltage Gated Sodium Channel InhibitionEfficient enzymatic cyclization of an inhibitory cystine knot-containing peptideTyrosine-rich conopeptides affect voltage-gated K+ channels.Evolution of separate predation- and defence-evoked venoms in carnivorous cone snailsA diverse family of novel peptide toxins from an unusual cone snail, Conus californicus.Membrane-tethered ligands: tools for cell-autonomous pharmacological manipulation of biological circuits.An in vivo tethered toxin approach for the cell-autonomous inactivation of voltage-gated sodium channel currents in nociceptors.Conotoxin gene superfamilies.μ-Conotoxins that differentially block sodium channels NaV1.1 through 1.8 identify those responsible for action potentials in sciatic nervemuO-conotoxin MrVIB selectively blocks Nav1.8 sensory neuron specific sodium channels and chronic pain behavior without motor deficitsNavβ subunits modulate the inhibition of Nav1.8 by the analgesic gating modifier μO-conotoxin MrVIBBiophysical properties of Na(v) 1.8/Na(v) 1.2 chimeras and inhibition by µO-conotoxin MrVIB.Highly Constrained Bicyclic Scaffolds for the Discovery of Protease-Stable Peptides via mRNA Display.Conotoxins targeting neuronal voltage-gated sodium channel subtypes: potential analgesics?Development of a μO-Conotoxin Analogue with Improved Lipid Membrane Interactions and Potency for the Analgesic Sodium Channel NaV1.8.Therapeutic potential of conopeptides.Animal toxins influence voltage-gated sodium channel function.Therapeutic conotoxins: a US patent literature survey.Kalata B8, a novel antiviral circular protein, exhibits conformational flexibility in the cystine knot motifµ-Conotoxins Modulating Sodium Currents in Pain Perception and Transmission: A Therapeutic Potential.Molecular Engineering of Conus Peptides as Therapeutic Leads.Conotoxins: Therapeutic Potential and Application.Neuronally micro-conotoxins from Conus striatus utilize an alpha-helical motif to target mammalian sodium channels.Marine Toxins That Target Voltage-gated Sodium Channels.Conopressin-T from Conus tulipa reveals an antagonist switch in vasopressin-like peptides.Tethered-toxin debut gets cold reception.The muO-conotoxin MrVIA inhibits voltage-gated sodium channels by associating with domain-3.Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.Toxin structures as evolutionary tools: Using conserved 3D folds to study the evolution of rapidly evolving peptides.
P2860
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P2860
Structures of muO-conotoxins from Conus marmoreus. I nhibitors of tetrodotoxin (TTX)-sensitive and TTX-resistant sodium channels in mammalian sensory neurons.
description
2004 nî lūn-bûn
@nan
2004 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մարտին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Structures of muO-conotoxins f ...... in mammalian sensory neurons.
@ast
Structures of muO-conotoxins f ...... in mammalian sensory neurons.
@en
type
label
Structures of muO-conotoxins f ...... in mammalian sensory neurons.
@ast
Structures of muO-conotoxins f ...... in mammalian sensory neurons.
@en
prefLabel
Structures of muO-conotoxins f ...... in mammalian sensory neurons.
@ast
Structures of muO-conotoxins f ...... in mammalian sensory neurons.
@en
P2860
P50
P356
P1476
Structures of muO-conotoxins f ...... s in mammalian sensory neurons
@en
P2093
Linda Thomas
P2860
P304
25774-25782
P356
10.1074/JBC.M313002200
P407
P577
2004-03-24T00:00:00Z