DNA polymerase lambda can elongate on DNA substrates mimicking non-homologous end joining and interact with XRCC4-ligase IV complex.
about
Phosphorylation of human DNA polymerase lambda by the cyclin-dependent kinase Cdk2/cyclin A complex is modulated by its association with proliferating cell nuclear antigenCharacterization of SpPol4, a unique X-family DNA polymerase in Schizosaccharomyces pombe.Structure-function studies of DNA polymerase λStructural insight into the substrate specificity of DNA Polymerase muSolution Structure of Polymerase μ's BRCT Domain Reveals an Element Essential for Its Role in Nonhomologous End Joining †A fidelity mechanism in DNA polymerase lambda promotes error-free bypass of 8-oxo-dGEnd-bridging is required for pol mu to efficiently promote repair of noncomplementary ends by nonhomologous end joiningCharacterization of a natural mutator variant of human DNA polymerase lambda which promotes chromosomal instability by compromising NHEJDNA joint dependence of pol X family polymerase action in nonhomologous end joiningDNA elongation by the human DNA polymerase lambda polymerase and terminal transferase activities are differentially coordinated by proliferating cell nuclear antigen and replication protein AInvolvement of AtPolλ in the repair of high salt- and DNA cross-linking agent-induced double strand breaks in Arabidopsis.A novel mechanism of sugar selection utilized by a human X-family DNA polymerase.Identification of critical residues for the tight binding of both correct and incorrect nucleotides to human DNA polymerase λN-terminal domains of human DNA polymerase lambda promote primer realignment during translesion DNA synthesis.Efficiency and fidelity of human DNA polymerases λ and β during gap-filling DNA synthesis.DNA pol λ's extraordinary ability to stabilize misaligned DNA.Arabidopsis DNA polymerase lambda mutant is mildly sensitive to DNA double strand breaks but defective in integration of a transgene.Promiscuous mismatch extension by human DNA polymerase lambdaAdditive effects of SbcCD and PolX deficiencies in the in vivo repair of DNA double-strand breaks in Deinococcus radioduransMicrohomology-mediated DNA strand annealing and elongation by human DNA polymerases λ and β on normal and repetitive DNA sequences.The X family portrait: structural insights into biological functions of X family polymerases.Nucleotide binding interactions modulate dNTP selectivity and facilitate 8-oxo-dGTP incorporation by DNA polymerase lambda.Control of DNA polymerase lambda stability by phosphorylation and ubiquitination during the cell cycle.A comparison of BRCT domains involved in nonhomologous end-joining: introducing the solution structure of the BRCT domain of polymerase lambda.The interplay of DNA polymerase λ in diverse DNA damage repair pathways in higher plant genome in response to environmental and genotoxic stress factors.Pol zeta ablation in B cells impairs the germinal center reaction, class switch recombination, DNA break repair, and genome stability.Probing conformational changes of human DNA polymerase lambda using mass spectrometry-based protein footprintingRelationship between conformational changes in pol lambda's active site upon binding incorrect nucleotides and mismatch incorporation rates.Polymerases in nonhomologous end joining: building a bridge over broken chromosomes.DNA polymerases in nonhomologous end joining: are there any benefits to standing out from the crowd?Resolution of complex ends by Nonhomologous end joining - better to be lucky than good?DNA stabilization at the Bacillus subtilis PolX core--a binding model to coordinate polymerase, AP-endonuclease and 3'-5' exonuclease activities.A specific N-terminal extension of the 8 kDa domain is required for DNA end-bridging by human Polμ and Polλ.DNA-binding determinants promoting NHEJ by human Polμ.The DNA polymerase lambda is required for the repair of non-compatible DNA double strand breaks by NHEJ in mammalian cells.Polμ tumor variants decrease the efficiency and accuracy of NHEJ.Editing of misaligned 3'-termini by an intrinsic 3'-5' exonuclease activity residing in the PHP domain of a family X DNA polymerase.Nonhomologous End-Joining (NHEJ)Processing of DNA for nonhomologous end-joining is controlled by kinase activity and XRCC4/ligase IV.XRCC4:LIG4; NHEJ1 and POLL or POLM bind DNA DSBs in NHEJ
P2860
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P2860
DNA polymerase lambda can elongate on DNA substrates mimicking non-homologous end joining and interact with XRCC4-ligase IV complex.
description
2004 nî lūn-bûn
@nan
2004 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
DNA polymerase lambda can elon ...... with XRCC4-ligase IV complex.
@ast
DNA polymerase lambda can elon ...... with XRCC4-ligase IV complex.
@en
DNA polymerase lambda can elon ...... with XRCC4-ligase IV complex.
@nl
type
label
DNA polymerase lambda can elon ...... with XRCC4-ligase IV complex.
@ast
DNA polymerase lambda can elon ...... with XRCC4-ligase IV complex.
@en
DNA polymerase lambda can elon ...... with XRCC4-ligase IV complex.
@nl
altLabel
DNA polymerase lambda can elon ...... t with XRCC4-ligase IV complex
@en
prefLabel
DNA polymerase lambda can elon ...... with XRCC4-ligase IV complex.
@ast
DNA polymerase lambda can elon ...... with XRCC4-ligase IV complex.
@en
DNA polymerase lambda can elon ...... with XRCC4-ligase IV complex.
@nl
P1476
DNA polymerase lambda can elon ...... with XRCC4-ligase IV complex.
@en
P2093
P304
P356
10.1016/J.BBRC.2004.09.002
P407
P577
2004-10-29T00:00:00Z