Identification of the yeast TOP3 gene product as a single strand-specific DNA topoisomerase.
about
Human TOP3: a single-copy gene encoding DNA topoisomerase IIIStructure and function of type II DNA topoisomerasesDisruption of mechanisms that prevent rereplication triggers a DNA damage responseInteraction between the N-terminus of human topoisomerase I and SV40 large T antigenOverexpression of a truncated human topoisomerase III partially corrects multiple aspects of the ataxia-telangiectasia phenotypeSlx1-Slx4 is a second structure-specific endonuclease functionally redundant with Sgs1-Top3.Functional overlap between Sgs1-Top3 and the Mms4-Mus81 endonucleaseA genomic study of the bipolar bud site selection pattern in Saccharomyces cerevisiae.Yeast Rmi1/Nce4 controls genome stability as a subunit of the Sgs1-Top3 complex.Binding and activation of DNA topoisomerase III by the Rmi1 subunit.Effects of yeast DNA topoisomerase III on telomere structure.The yeast type I topoisomerase Top3 interacts with Sgs1, a DNA helicase homolog: a potential eukaryotic reverse gyraseTopoisomerase 3alpha and RMI1 suppress somatic crossovers and are essential for resolution of meiotic recombination intermediates in Arabidopsis thalianaIsolation and characterization of a gene encoding DNA topoisomerase I in Drosophila melanogaster.Topoisomerase IIIalpha and Bloom's helicase can resolve a mobile double Holliday junction substrate through convergent branch migration.Mapping the DNA topoisomerase III binding domain of the Sgs1 DNA helicase.The essential role of yeast topoisomerase III in meiosis depends on recombination.Association of yeast DNA topoisomerase III and Sgs1 DNA helicase: studies of fusion proteins.Sgs1 helicase activity is required for mitotic but apparently not for meiotic functions.Isolation of mutants of Saccharomyces cerevisiae requiring DNA topoisomerase I.Preferential cleavage of plasmid-based R-loops and D-loops by Drosophila topoisomerase IIIbetaTopoisomerase III is required for accurate DNA replication and chromosome segregation in Schizosaccharomyces pombeThe dissolution of double Holliday junctions.Alternate pathways involving Sgs1/Top3, Mus81/ Mms4, and Srs2 prevent formation of toxic recombination intermediates from single-stranded gaps created by DNA replication.A novel family of TRF (DNA topoisomerase I-related function) genes required for proper nuclear segregationDNA topoisomerase III localizes to centromeres and affects centromeric CENP-A levels in fission yeast.The absence of Top3 reveals an interaction between the Sgs1 and Pif1 DNA helicases in Saccharomyces cerevisiae.Top3-Rmi1 dissolve Rad51-mediated D loops by a topoisomerase-based mechanism.The mechanism of Mus81-Mms4 cleavage site selection distinguishes it from the homologous endonuclease Rad1-Rad10.RecQ helicases: suppressors of tumorigenesis and premature aging.Secondary metabolites as DNA topoisomerase inhibitors: A new era towards designing of anticancer drugs.Mammalian DNA topoisomerase IIIalpha is essential in early embryogenesis.Mice lacking DNA topoisomerase IIIbeta develop to maturity but show a reduced mean lifespan.DNA topoisomerase III from the hyperthermophilic archaeon Sulfolobus solfataricus with specific DNA cleavage activityTopoisomerase assaysThe rRNA-encoding DNA array has an altered structure in topoisomerase I mutants of Saccharomyces cerevisiaeTopoisomerase I involvement in illegitimate recombination in Saccharomyces cerevisiae.Mitochondrial topoisomerase II activity is essential for kinetoplast DNA minicircle segregation.Analysis of DNA relaxation and cleavage activities of recombinant Mycobacterium tuberculosis DNA topoisomerase I from a new expression and purification protocol.Resolution by unassisted Top3 points to template switch recombination intermediates during DNA replication.
P2860
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P2860
Identification of the yeast TOP3 gene product as a single strand-specific DNA topoisomerase.
description
1992 nî lūn-bûn
@nan
1992 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
Identification of the yeast TO ...... nd-specific DNA topoisomerase.
@ast
Identification of the yeast TO ...... nd-specific DNA topoisomerase.
@en
Identification of the yeast TO ...... nd-specific DNA topoisomerase.
@nl
type
label
Identification of the yeast TO ...... nd-specific DNA topoisomerase.
@ast
Identification of the yeast TO ...... nd-specific DNA topoisomerase.
@en
Identification of the yeast TO ...... nd-specific DNA topoisomerase.
@nl
prefLabel
Identification of the yeast TO ...... nd-specific DNA topoisomerase.
@ast
Identification of the yeast TO ...... nd-specific DNA topoisomerase.
@en
Identification of the yeast TO ...... nd-specific DNA topoisomerase.
@nl
P3181
P1476
Identification of the yeast TO ...... nd-specific DNA topoisomerase.
@en
P3181
P407
P577
1992-08-25T00:00:00Z