Mice lacking DNA topoisomerase IIIbeta develop to maturity but show a reduced mean lifespan.
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Cellular roles of dna topoisomerases: a molecular perspectiveBacillus cereus DNA topoisomerase I and IIIalpha: purification, characterization and complementation of Escherichia coli TopoIII activity.A "Pedi" Cures All: Toenail Trimming and the Treatment of Ulcerative Dermatitis in MiceMutations in homologous recombination genes rescue top3 slow growth in Saccharomyces cerevisiae.A genetic screen for top3 suppressors in Saccharomyces cerevisiae identifies SHU1, SHU2, PSY3 and CSM2: four genes involved in error-free DNA repair.Accelerating aging by mouse reverse genetics: a rational approach to understanding longevityTopoisomerase 3alpha and RMI1 suppress somatic crossovers and are essential for resolution of meiotic recombination intermediates in Arabidopsis thalianaInfertility and aneuploidy in mice lacking a type IA DNA topoisomerase III betaRegulated splicing of the fibronectin EDA exon is essential for proper skin wound healing and normal lifespanDrosophila melanogaster topoisomerase IIIalpha preferentially relaxes a positively or negatively supercoiled bubble substrate and is essential during development.Topoisomerase IIIalpha and Bloom's helicase can resolve a mobile double Holliday junction substrate through convergent branch migration.Topoisomerase 3β is the major topoisomerase for mRNAs and linked to neurodevelopment and mental dysfunction.TOPO3alpha influences antigenic variation by monitoring expression-site-associated VSG switching in Trypanosoma brucei.Preferential cleavage of plasmid-based R-loops and D-loops by Drosophila topoisomerase IIIbetaMethanosarcina acetivorans C2A topoisomerase IIIα, an archaeal enzyme with promiscuity in divalent cation dependence.The influence of genes on the aging process of mice: a statistical assessment of the genetics of aging.Mice as a mammalian model for research on the genetics of agingThe absence of Top3 reveals an interaction between the Sgs1 and Pif1 DNA helicases in Saccharomyces cerevisiae.Development of autoimmunity in mice lacking DNA topoisomerase 3betaA new Drosophila gene wh (wuho) with WD40 repeats is essential for spermatogenesis and has maximal expression in hub cells.Defective p53 engagement after the induction of DNA damage in cells deficient in topoisomerase 3betaIron chelators with topoisomerase-inhibitory activity and their anticancer applications.DNA Topology and Topoisomerases: Teaching a "Knotty" Subject.Top3β is an RNA topoisomerase that works with fragile X syndrome protein to promote synapse formation.Structural basis of the interaction between Topoisomerase IIIβ and the TDRD3 auxiliary factorTrypanosomatids topoisomerase re-visited. New structural findings and role in drug discoveryArginine methylation facilitates the recruitment of TOP3B to chromatin to prevent R loop accumulation.Bloom helicase and DNA topoisomerase IIIalpha are involved in the dissolution of sister chromatids.Topoisomerases and the regulation of neural function.Essential functions of C terminus of Drosophila Topoisomerase IIIα in double holliday junction dissolutionIdentification of a Functional Type IA Topoisomerase, LdTopIIIβ, from Kinetoplastid Parasite Leishmania donovani.DNA topoisomerase II is required for the G0-to-S phase transition in Drosophila Schneider cells, but not in yeast.Generation of double-stranded breaks in hypernegatively supercoiled DNA by Drosophila topoisomerase IIIbeta, a type IA enzyme.An Assay for Detecting RNA Topoisomerase Activity.Type IA topoisomerases can be "magicians" for both DNA and RNA in all domains of life.Viability of Escherichia coli topA mutants lacking DNA topoisomerase I.Developing T lymphocytes are uniquely sensitive to a lack of topoisomerase III alpha.Characterization of a unique type IA topoisomerase in Bacillus cereus.
P2860
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P2860
Mice lacking DNA topoisomerase IIIbeta develop to maturity but show a reduced mean lifespan.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Mice lacking DNA topoisomerase ...... show a reduced mean lifespan.
@ast
Mice lacking DNA topoisomerase ...... show a reduced mean lifespan.
@en
type
label
Mice lacking DNA topoisomerase ...... show a reduced mean lifespan.
@ast
Mice lacking DNA topoisomerase ...... show a reduced mean lifespan.
@en
prefLabel
Mice lacking DNA topoisomerase ...... show a reduced mean lifespan.
@ast
Mice lacking DNA topoisomerase ...... show a reduced mean lifespan.
@en
P2860
P356
P1476
Mice lacking DNA topoisomerase ...... show a reduced mean lifespan.
@en
P2093
P2860
P304
P356
10.1073/PNAS.101132498
P407
P577
2001-05-01T00:00:00Z