A genome-wide screen for regulators of TORC1 in response to amino acid starvation reveals a conserved Npr2/3 complex
about
Discovery of Novel DENN Proteins: Implications for the Evolution of Eukaryotic Intracellular Membrane Structures and Human DiseaseA Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1The product of C9orf72, a gene strongly implicated in neurodegeneration, is structurally related to DENN Rab-GEFsSelective regulation of autophagy by the Iml1-Npr2-Npr3 complex in the absence of nitrogen starvationConserved regulators of Rag GTPases orchestrate amino acid-dependent TORC1 signalingLeucine and mTORC1: a complex relationshipDiscovery of new Longin and Roadblock domains that form platforms for small GTPases in Ragulator and TRAPP-IINutritional control of growth and development in yeastNpr2, yeast homolog of the human tumor suppressor NPRL2, is a target of Grr1 required for adaptation to growth on diverse nitrogen sources.The role of autophagy in genome stability through suppression of abnormal mitosis under starvationMolecular architecture and function of the SEA complex, a modulator of the TORC1 pathway.Reciprocal conversion of Gtr1 and Gtr2 nucleotide-binding states by Npr2-Npr3 inactivates TORC1 and induces autophagy.SEACing the GAP that nEGOCiates TORC1 activation: evolutionary conservation of Rag GTPase regulation.Ksp1 kinase regulates autophagy via the target of rapamycin complex 1 (TORC1) pathway.A conserved coatomer-related complex containing Sec13 and Seh1 dynamically associates with the vacuole in Saccharomyces cerevisiae.Amino acid deprivation inhibits TORC1 through a GTPase-activating protein complex for the Rag family GTPase Gtr1.Methionine inhibits autophagy and promotes growth by inducing the SAM-responsive methylation of PP2AThe yeast Sks1p kinase signaling network regulates pseudohyphal growth and glucose responseThe GATOR2 Component Wdr24 Regulates TORC1 Activity and Lysosome FunctionIdentification of a Novel Regulatory Mechanism of Nutrient Transport Controlled by TORC1-Npr1-Amu1/Par32Nprl3 is required for normal development of the cardiovascular systemThe effector candidate repertoire of the arbuscular mycorrhizal fungus Rhizophagus clarusExperimental and Computational Analysis of a Large Protein Network That Controls Fat Storage Reveals the Design Principles of a Signaling NetworkConvergence of ubiquitylation and phosphorylation signaling in rapamycin-treated yeast cells.The TORC1 inhibitors Nprl2 and Nprl3 mediate an adaptive response to amino-acid starvation in Drosophila.A multi-omic map of the lipid-producing yeast Rhodosporidium toruloidesState transitions in the TORC1 signaling pathway and information processing in Saccharomyces cerevisiaeTORC1 regulators Iml1/GATOR1 and GATOR2 control meiotic entry and oocyte development in Drosophila.A genome-wide screen for identifying all regulators of a target gene.Inferring the effective TOR-dependent network: a computational study in yeast.Npr2 inhibits TORC1 to prevent inappropriate utilization of glutamine for biosynthesis of nitrogen-containing metabolitesGATA-Dependent Glutaminolysis Drives Appressorium Formation in Magnaporthe oryzae by Suppressing TOR Inhibition of cAMP/PKA Signaling.SEA you later alli-GATOR--a dynamic regulator of the TORC1 stress response pathway.Branched-Chain Aminotransferases Control TORC1 Signaling in Saccharomyces cerevisiaeThe Loss of Lam2 and Npr2-Npr3 Diminishes the Vacuolar Localization of Gtr1-Gtr2 and Disinhibits TORC1 Activity in Fission YeastIdentifying Novel Candidate Genes Related to Apoptosis from a Protein-Protein Interaction Network.Genome-Wide Analysis of the TORC1 and Osmotic Stress Signaling Network in Saccharomyces cerevisiae.Multiple amino acid sensing inputs to mTORC1.Regulation of Hematopoiesis and Methionine Homeostasis by mTORC1 Inhibitor NPRL2A novel sphingolipid-TORC1 pathway critically promotes postembryonic development in Caenorhabditis elegans.
P2860
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P248
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P2860
A genome-wide screen for regulators of TORC1 in response to amino acid starvation reveals a conserved Npr2/3 complex
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
A genome-wide screen for regul ...... als a conserved Npr2/3 complex
@ast
A genome-wide screen for regul ...... als a conserved Npr2/3 complex
@en
A genome-wide screen for regul ...... ls a conserved Npr2/3 complex.
@nl
type
label
A genome-wide screen for regul ...... als a conserved Npr2/3 complex
@ast
A genome-wide screen for regul ...... als a conserved Npr2/3 complex
@en
A genome-wide screen for regul ...... ls a conserved Npr2/3 complex.
@nl
altLabel
A genome-wide screen for regul ...... als a conserved Npr2/3 complex
@en
prefLabel
A genome-wide screen for regul ...... als a conserved Npr2/3 complex
@ast
A genome-wide screen for regul ...... als a conserved Npr2/3 complex
@en
A genome-wide screen for regul ...... ls a conserved Npr2/3 complex.
@nl
P2860
P3181
P1433
P1476
A genome-wide screen for regul ...... als a conserved Npr2/3 complex
@en
P2093
Ronald W Davis
Taavi K Neklesa
P2860
P304
P3181
P356
10.1371/JOURNAL.PGEN.1000515
P407
P577
2009-06-01T00:00:00Z