Modulation of notch signaling elicits signature tumors and inhibits hras1-induced oncogenesis in the mouse mammary epithelium - Wikidata - wikimedia - TriplyDB

Modulation of notch signaling elicits signature tumors and inhibits hras1-induced oncogenesis in the mouse mammary epithelium

Modulation of notch signaling elicits signature tumors and inhibits hras1-induced oncogenesis in the mouse mammary epithelium

http://www.wikidata.org/entity/Q35103047

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The notch ligand JAGGED1 as a target for anti-tumor therapy Main roads to melanoma The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer A Role for Notch Signalling in Breast Cancer and Endocrine Resistance Luminal progenitors restrict their lineage potential during mammary gland development Notch and Wnt signals cooperatively control cell proliferation and tumorigenesis in the intestine Dose-dependent induction of distinct phenotypic responses to Notch pathway activation in mammary epithelial cells Notch and Mef2 synergize to promote proliferation and metastasis through JNK signal activation in Drosophila Hypoxia potentiates Notch signaling in breast cancer leading to decreased E-cadherin expression and increased cell migration and invasion NOTCH1 inhibition in vivo results in mammary tumor regression and reduced mammary tumorsphere-forming activity in vitro Mammary gene expression profiles during an intramammary challenge reveal potential mechanisms linking negative energy balance with impaired immune response Notch inhibitors for cancer treatment.Trp53 regulates Notch 4 signaling through Mdm2.Role of Notch and its oncogenic signaling crosstalk in breast cancer.Myc is a Notch1 transcriptional target and a requisite for Notch1-induced mammary tumorigenesis in mice.Notch1 signaling regulates the epithelial-mesenchymal transition and invasion of breast cancer in a Slug-dependent manner Overexpression of activated murine Notch1 and Notch3 in transgenic mice blocks mammary gland development and induces mammary tumors Hypoxia-induced Jagged2 promotes breast cancer metastasis and self-renewal of cancer stem-like cells.Aspartate β-Hydroxylase expression promotes a malignant pancreatic cellular phenotype Cross-talk between notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches Regulation of DCIS to invasive breast cancer progression by Singleminded-2s (SIM2s).Quantitative DNA hypomethylation of ligand Jagged1 and receptor Notch1 signifies occurrence and progression of breast carcinoma.Notch promotes recurrence of dormant tumor cells following HER2/neu-targeted therapy.Gamma secretase inhibitor enhances sensitivity to doxorubicin in MDA-MB-231 cells.Therapeutic approaches to modulating Notch signaling: current challenges and future prospects.Regulation of Notch Signaling by an Evolutionary Conserved DEAD Box RNA Helicase, Maheshvara in Drosophila melanogaster.Notch signalling in vertebrate neural development.Notch signaling in breast cancer and tumor angiogenesis: cross-talk and therapeutic potentials.Selection of p53-Deficient Stromal Cells in the Tumor Microenvironment Targeting signal transduction in pancreatic cancer treatment.Gamma secretase inhibitors of Notch signaling Notch-1 activates estrogen receptor-alpha-dependent transcription via IKKalpha in breast cancer cells.Ha-Ras transformation of MCF10A cells leads to repression of Singleminded-2s through NOTCH and C/EBPbeta.Mammary involution and breast cancer risk: transgenic models and clinical studies.Notch3 marks clonogenic mammary luminal progenitor cells in vivo.Notch activation stimulates migration of breast cancer cells and promotes tumor growth Notch and disease: a growing field.Notch signaling in pancreatic cancer: oncogene or tumor suppressor?Cyclin D1 is a direct target of JAG1-mediated Notch signaling in breast cancer.Notch1 is required for Kras-induced lung adenocarcinoma and controls tumor cell survival via p53

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Modulation of notch signaling elicits signature tumors and inhibits hras1-induced oncogenesis in the mouse mammary epithelium

http://www.wikidata.org/entity/Q35103047

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2004 nî lūn-bûn

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2004 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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2004 թվականի օգոստոսին հրատարակված գիտական հոդված

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Modulation of notch signaling ...... n the mouse mammary epithelium

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Modulation of notch signaling ...... n the mouse mammary epithelium

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Modulation of notch signaling ...... n the mouse mammary epithelium

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P2093

Hippokratis Kiaris

http://www.w3.org/2001/XMLSchema#string

Lisa M Grimm

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Matthias Szabolcs

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Peter Fisher

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P2860

Human deltex is a conserved regulator of Notch signalling

TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

Deltex acts as a positive regulator of Notch signaling through interactions with the Notch ankyrin repeats

Sequence of the notch locus of Drosophila melanogaster: relationship of the encoded protein to mammalian clotting and growth factors

Is there a role for Notch signalling in human breast cancer?

Notch signaling: cell fate control and signal integration in development

Involvement of Notch1 in the development of mouse mammary tumors

LIN-12/Notch signaling: lessons from worms and flies

Signalling downstream of activated mammalian Notch

Modulation of the notch signaling by Mash1 and Dlx1/2 regulates sequential specification and differentiation of progenitor cell types in the subcortical telencephalon

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Spyros Artavanis-Tsakonas

Katerina Politi

Argiris Efstratiadis

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8433020

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1618582

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