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Essential requirement for two-pore channel 1 in NAADP-mediated calcium signalingNicotinic acid adenine dinucleotide phosphate regulates skeletal muscle differentiation via action at two-pore channelsSperm express a Ca2+-regulated NAADP synthaseThe biphasic increase of PIP2 in the fertilized eggs of starfish: new roles in actin polymerization and Ca2+ signalingDomain assembly of NAADP-gated two-pore channelsAcidic residues at the active sites of CD38 and ADP-ribosyl cyclase determine nicotinic acid adenine dinucleotide phosphate (NAADP) synthesis and hydrolysis activitiesFertilization and nicotinic acid adenine dinucleotide phosphate induce pH changes in acidic Ca(2+) stores in sea urchin eggsAcidic calcium stores open for business: expanding the potential for intracellular Ca2+ signalingBidirectional Ca²⁺ signaling occurs between the endoplasmic reticulum and acidic organellesThe ecto-enzyme CD38 is a nicotinic acid adenine dinucleotide phosphate (NAADP) synthase that couples receptor activation to Ca2+ mobilization from lysosomes in pancreatic acinar cells.High resolution structural evidence suggests the Sarcoplasmic Reticulum forms microdomains with Acidic Stores (lysosomes) in the heartMolecular characterization of a novel intracellular ADP-ribosyl cyclase.Calcium signaling via two-pore channels: local or global, that is the question.TPCs: Endolysosomal channels for Ca2+ mobilization from acidic organelles triggered by NAADPA functional role for nicotinic acid adenine dinucleotide phosphate in oxytocin-mediated contraction of uterine smooth muscle from rat.The calcium-mobilizing messenger nicotinic acid adenine dinucleotide phosphate participates in sperm activation by mediating the acrosome reactionCalcium channels in the development, maturation, and function of spermatozoa.Two-pore channels: Regulation by NAADP and customized roles in triggering calcium signalsNAADP receptors.Effects of ionomycin on egg activation and early development in starfish.Acidic NAADP-sensitive calcium stores in the endothelium: agonist-specific recruitment and role in regulating blood pressure.VEGF-induced neoangiogenesis is mediated by NAADP and two-pore channel-2-dependent Ca2+ signaling.Two-Pore Channels: Lessons from Mutant Mouse ModelsTwo pore channel 2 differentially modulates neural differentiation of mouse embryonic stem cells.Triazine dyes are agonists of the NAADP receptor.Calcium at fertilization and in early developmentThe NAADP receptor: commentary on Billington et al.Nicotinic acid adenine dinucleotide phosphate (NAADP)-mediated calcium signaling.Calcium pathway machinery at fertilization in echinodermsRefinement of a radioreceptor binding assay for nicotinic acid adenine dinucleotide phosphate.Calcium signalling in early embryos.The acid test: the discovery of two-pore channels (TPCs) as NAADP-gated endolysosomal Ca(2+) release channels.NAADP and the two-pore channel protein 1 participate in the acrosome reaction in mammalian spermatozoa.The endo-lysosomal system as an NAADP-sensitive acidic Ca(2+) store: role for the two-pore channels.Cyclic ADP-ribose and NAADP: fraternal twin messengers for calcium signaling.Physiological roles of NAADP-mediated Ca2+ signaling.Actin, more than just a housekeeping protein at the scene of fertilization.Molecular mechanisms of endolysosomal Ca2+ signalling in health and disease.Cyclic ADP-ribose and nicotinic acid adenine dinucleotide phosphate (NAADP) as messengers for calcium mobilization.Comparative biology of sperm factors and fertilization-induced calcium signals across the animal kingdom.
P2860
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P2860
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Sperm deliver a new second messenger: NAADP
@ast
Sperm deliver a new second messenger: NAADP
@en
Sperm deliver a new second messenger: NAADP
@nl
type
label
Sperm deliver a new second messenger: NAADP
@ast
Sperm deliver a new second messenger: NAADP
@en
Sperm deliver a new second messenger: NAADP
@nl
prefLabel
Sperm deliver a new second messenger: NAADP
@ast
Sperm deliver a new second messenger: NAADP
@en
Sperm deliver a new second messenger: NAADP
@nl
P50
P1433
P1476
Sperm deliver a new second messenger: NAADP
@en
P2093
Grant C Churchill
Justyn M Thomas
P356
10.1016/S0960-9822(03)00002-2
P407
P577
2003-01-21T00:00:00Z