Active PIKfyve associates with and promotes the membrane attachment of the late endosome-to-trans-Golgi network transport factor Rab9 effector p40
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The mammalian phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) regulates endosome-to-TGN retrograde transport.Core protein machinery for mammalian phosphatidylinositol 3,5-bisphosphate synthesis and turnover that regulates the progression of endosomal transport. Novel Sac phosphatase joins the ArPIKfyve-PIKfyve complexKinesin adapter JLP links PIKfyve to microtubule-based endosome-to-trans-Golgi network traffic of furinRab9 GTPase is required for replication of human immunodeficiency virus type 1, filoviruses, and measles virus.Mutations in PIP5K3 are associated with François-Neetens mouchetée fleck corneal dystrophyThe phosphoinositide kinase PIKfyve/Fab1p regulates terminal lysosome maturation in Caenorhabditis elegansA mammalian ortholog of Saccharomyces cerevisiae Vac14 that associates with and up-regulates PIKfyve phosphoinositide 5-kinase activityInhibition of the PtdIns(5) kinase PIKfyve disrupts intracellular replication of Salmonella.A selective PIKfyve inhibitor blocks PtdIns(3,5)P(2) production and disrupts endomembrane transport and retroviral budding.PIKfyve: Partners, significance, debates and paradoxesArPIKfyve-PIKfyve interaction and role in insulin-regulated GLUT4 translocation and glucose transport in 3T3-L1 adipocytesArPIKfyve homomeric and heteromeric interactions scaffold PIKfyve and Sac3 in a complex to promote PIKfyve activity and functionalityTIP47 is a key effector for Rab9 localizationPhosphatidylinositol 3,5-bisphosphate: low abundance, high significanceCharcot-Marie-Tooth disease and intracellular trafficEndosome maturationRole of Rab GTPases in membrane traffic and cell physiologyRabs and their effectors: achieving specificity in membrane trafficInhibition of PIKfyve prevents myocardial apoptosis and hypertrophy through activation of SIRT3 in obese mice.APP controls the formation of PI(3,5)P(2) vesicles through its binding of the PIKfyve complexEndosomal phosphoinositides and human diseases.YM201636, an inhibitor of retroviral budding and PIKfyve-catalyzed PtdIns(3,5)P2 synthesis, halts glucose entry by insulin in adipocytes.Phosphatidylinositol-3,5-bisphosphate: no longer the poor PIP2.The nucleophosmin-anaplastic lymphoma kinase oncogene interacts, activates, and uses the kinase PIKfyve to increase invasiveness.PIKfyve inhibition interferes with phagosome and endosome maturation in macrophages.Distinct Requirements for Vacuolar Protein Sorting 34 Downstream Effector Phosphatidylinositol 3-Phosphate 5-Kinase in Podocytes Versus Proximal Tubular Cells.The Vac14-interaction network is linked to regulators of the endolysosomal and autophagic pathway.
P2860
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P2860
Active PIKfyve associates with and promotes the membrane attachment of the late endosome-to-trans-Golgi network transport factor Rab9 effector p40
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2003 nî lūn-bûn
@nan
2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Active PIKfyve associates with ...... sport factor Rab9 effector p40
@ast
Active PIKfyve associates with ...... sport factor Rab9 effector p40
@en
Active PIKfyve associates with ...... sport factor Rab9 effector p40
@nl
type
label
Active PIKfyve associates with ...... sport factor Rab9 effector p40
@ast
Active PIKfyve associates with ...... sport factor Rab9 effector p40
@en
Active PIKfyve associates with ...... sport factor Rab9 effector p40
@nl
prefLabel
Active PIKfyve associates with ...... sport factor Rab9 effector p40
@ast
Active PIKfyve associates with ...... sport factor Rab9 effector p40
@en
Active PIKfyve associates with ...... sport factor Rab9 effector p40
@nl
P2093
P2860
P356
P1476
Active PIKfyve associates with ...... sport factor Rab9 effector p40
@en
P2093
Aleric Soans
Diego Sbrissa
Jason Fligger
Krzysztof Mlak
Ognian C Ikonomov
Robert Deeb
Russell L Finley
P2860
P304
P356
10.1074/JBC.M307260200
P407
P577
2003-12-19T00:00:00Z