Requirement for PIKfyve enzymatic activity in acute and long-term insulin cellular effects
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C5L2 is a functional receptor for acylation-stimulating proteinCore protein machinery for mammalian phosphatidylinositol 3,5-bisphosphate synthesis and turnover that regulates the progression of endosomal transport. Novel Sac phosphatase joins the ArPIKfyve-PIKfyve complexKinesin adapter JLP links PIKfyve to microtubule-based endosome-to-trans-Golgi network traffic of furinFunctional dissociation between PIKfyve-synthesized PtdIns5P and PtdIns(3,5)P2 by means of the PIKfyve inhibitor YM201636The phosphoinositide kinase PIKfyve is vital in early embryonic development: preimplantation lethality of PIKfyve-/- embryos but normality of PIKfyve+/- micePIKfyve: Partners, significance, debates and paradoxesArPIKfyve-PIKfyve interaction and role in insulin-regulated GLUT4 translocation and glucose transport in 3T3-L1 adipocytesArPIKfyve homomeric and heteromeric interactions scaffold PIKfyve and Sac3 in a complex to promote PIKfyve activity and functionalityPhosphoinositides: Key modulators of energy metabolismActive PIKfyve associates with and promotes the membrane attachment of the late endosome-to-trans-Golgi network transport factor Rab9 effector p40PIKfyve negatively regulates exocytosis in neurosecretory cellsPIKfyve, a class III PI kinase, is the target of the small molecular IL-12/IL-23 inhibitor apilimod and a player in Toll-like receptor signalingMuscle-specific Pikfyve gene disruption causes glucose intolerance, insulin resistance, adiposity, and hyperinsulinemia but not muscle fiber-type switchingGLUT4 traffic through an ESCRT-III-dependent sorting compartment in adipocytes.Curcumin diminishes the impacts of hyperglycemia on the activation of hepatic stellate cells by suppressing membrane translocation and gene expression of glucose transporter-2Microarray characterization of gene expression changes in blood during acute ethanol exposureSac3 is an insulin-regulated phosphatidylinositol 3,5-bisphosphate phosphatase: gain in insulin responsiveness through Sac3 down-regulation in adipocytesExploring phosphatidylinositol 5-phosphate 4-kinase function.Class III PI 3-kinase is the main source of PtdIns3P substrate and membrane recruitment signal for PIKfyve constitutive function in podocyte endomembrane homeostasisPtdIns5P: news and views of its appearance, disappearance and deeds.Turning signals on and off: GLUT4 traffic in the insulin-signaling highway.Plentiful PtdIns5P from scanty PtdIns(3,5)P2 or from ample PtdIns? PIKfyve-dependent models: Evidence and speculation (response to: DOI 10.1002/bies.201300012).APP controls the formation of PI(3,5)P(2) vesicles through its binding of the PIKfyve complexPhosphoinositides in insulin action on GLUT4 dynamics: not just PtdIns(3,4,5)P3.Unexpected severe consequences of Pikfyve deletion by aP2- or Aq-promoter-driven Cre expression for glucose homeostasis and mammary gland development.The CMT4B disease-causing proteins MTMR2 and MTMR13/SBF2 regulate AKT signallingThe nucleophosmin-anaplastic lymphoma kinase oncogene interacts, activates, and uses the kinase PIKfyve to increase invasiveness.Active vacuolar H+ ATPase and functional cycle of Rab5 are required for the vacuolation defect triggered by PtdIns(3,5)P2 loss under PIKfyve or Vps34 deficiency.Curcumin directly inhibits the transport activity of GLUT1Metabolic Reprogramming by the PI3K-Akt-mTOR Pathway in Cancer.Vac14 protein multimerization is a prerequisite step for Fab1 protein complex assembly and functionCurcumin Improves Palmitate-Induced Insulin Resistance in Human Umbilical Vein Endothelial Cells by Maintaining Proteostasis in Endoplasmic ReticulumPolyphenols and their effects on diabetes management: A review.Curcumin, Cardiometabolic Health and Dementia
P2860
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P2860
Requirement for PIKfyve enzymatic activity in acute and long-term insulin cellular effects
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2002 nî lūn-bûn
@nan
2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Requirement for PIKfyve enzyma ...... -term insulin cellular effects
@ast
Requirement for PIKfyve enzyma ...... -term insulin cellular effects
@en
Requirement for PIKfyve enzyma ...... -term insulin cellular effects
@nl
type
label
Requirement for PIKfyve enzyma ...... -term insulin cellular effects
@ast
Requirement for PIKfyve enzyma ...... -term insulin cellular effects
@en
Requirement for PIKfyve enzyma ...... -term insulin cellular effects
@nl
prefLabel
Requirement for PIKfyve enzyma ...... -term insulin cellular effects
@ast
Requirement for PIKfyve enzyma ...... -term insulin cellular effects
@en
Requirement for PIKfyve enzyma ...... -term insulin cellular effects
@nl
P2093
P3181
P356
P1433
P1476
Requirement for PIKfyve enzyma ...... -term insulin cellular effects
@en
P2093
Diego Sbrissa
Krzysztof Mlak
Ognian C Ikonomov
P304
P3181
P356
10.1210/EN.2002-220615
P407
P577
2002-12-01T00:00:00Z