Differential expression of the F-box proteins Skp2 and Skp2B in breast cancer
about
Acetylation-dependent regulation of Skp2 functionSkp2B attenuates p53 function by inhibiting prohibitinPhosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destructionSkp2: a novel potential therapeutic target for prostate cancerPhosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKBDeregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancerDrugging the undruggables: exploring the ubiquitin system for drug developmentTargeting the ubiquitin pathway for cancer treatmentSkp2B stimulates mammary gland development by inhibiting REA, the repressor of the estrogen receptorDistinct molecular mechanisms underlying clinically relevant subtypes of breast cancer: gene expression analyses across three different platformsNuclear translocation of Skp2 facilitates its destruction in response to TGFβ signaling.Curcumin exerts its antitumor activity through regulation of miR-7/Skp2/p21 in nasopharyngeal carcinoma cells.Skp2B overexpression alters a prohibitin-p53 axis and the transcription of PAPP-A, the protease of insulin-like growth factor binding protein 4Cytoplasmic Skp2 expression is associated with p-Akt1 and predicts poor prognosis in human breast carcinomasRoles of F-box proteins in cancerSCF Fbx4/alphaB-crystallin cyclin D1 ubiquitin ligase: a license to destroy.Skp2 is a promising therapeutic target in breast cancer.Phosphorylation by p38 mitogen-activated protein kinase promotes estrogen receptor α turnover and functional activity via the SCF(Skp2) proteasomal complex.The APC/C Ubiquitin Ligase: From Cell Biology to TumorigenesisSkp2 expression unfavorably impacts survival in resectable esophageal squamous cell carcinoma.FOXP3 is a novel transcriptional repressor for the breast cancer oncogene SKP2.BRCA1 inhibits AR-mediated proliferation of breast cancer cells through the activation of SIRT1Mitochondrial protein quality control by the proteasome involves ubiquitination and the protease OmiOver-expression of Skp2 is associated with resistance to preoperative doxorubicin-based chemotherapy in primary breast cancer.Skp2 is over-expressed in breast cancer and promotes breast cancer cell proliferationIdentification of acetylation-dependent regulatory mechanisms that govern the oncogenic functions of Skp2.Connexin Controls Cell-Cycle Exit and Cell Differentiation by Directly Promoting Cytosolic Localization and Degradation of E3 Ligase Skp2.Skp2 regulates subcellular localization of PPARγ by MEK signaling pathways in human breast cancerCurcumin inhibits cell growth and invasion and induces apoptosis through down-regulation of Skp2 in pancreatic cancer cellsSOD2 to SOD1 switch in breast cancer.Acquisition of epithelial-mesenchymal transition is associated with Skp2 expression in paclitaxel-resistant breast cancer cells.The role of FOXP3 in the development and metastatic spread of breast cancer.MicroRNA regulation of F-box proteins and its role in cancer.S-phase kinase-associated protein 2 promotes cell growth and motility in osteosarcoma cells.FBXO50 Enhances the Malignant Behavior of Gastric Cancer Cells.microRNA-186 inhibits cell proliferation and induces apoptosis in human esophageal squamous cell carcinoma by targeting SKP2.Downregulation of Skp2 inhibits the growth and metastasis of gastric cancer cells in vitro and in vivo.Skp2 and Skp2B team up against Rb and p53.Akt finds its new path to regulate cell cycle through modulating Skp2 activity and its destruction by APC/Cdh1.Cell cycle-dependent regulation of cytoglobin by Skp2.
P2860
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P2860
Differential expression of the F-box proteins Skp2 and Skp2B in breast cancer
description
2005 nî lūn-bûn
@nan
2005 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Differential expression of the F-box proteins Skp2 and Skp2B in breast cancer
@ast
Differential expression of the F-box proteins Skp2 and Skp2B in breast cancer
@en
Differential expression of the F-box proteins Skp2 and Skp2B in breast cancer
@nl
type
label
Differential expression of the F-box proteins Skp2 and Skp2B in breast cancer
@ast
Differential expression of the F-box proteins Skp2 and Skp2B in breast cancer
@en
Differential expression of the F-box proteins Skp2 and Skp2B in breast cancer
@nl
prefLabel
Differential expression of the F-box proteins Skp2 and Skp2B in breast cancer
@ast
Differential expression of the F-box proteins Skp2 and Skp2B in breast cancer
@en
Differential expression of the F-box proteins Skp2 and Skp2B in breast cancer
@nl
P2093
P3181
P356
P1433
P1476
Differential expression of the F-box proteins Skp2 and Skp2B in breast cancer
@en
P2093
Andreja Pirkmaier
Doris Germain
Susanne Radke
P2860
P2888
P304
P3181
P356
10.1038/SJ.ONC.1208328
P407
P577
2005-05-12T00:00:00Z
P5875
P6179
1022016152