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The expression of the ubiquitin ligase subunit Cks1 in human breast cancerAcetylation-dependent regulation of Skp2 functionCooperation of ERK and SCFSkp2 for MKP-1 destruction provides a positive feedback regulation of proliferating signalingRegulation of p27 degradation and S-phase progression by Ro52 RING finger proteinThe X protein of hepatitis B virus binds to the F box protein Skp2 and inhibits the ubiquitination and proteasomal degradation of c-MycIntegrative genomics analysis of chromosome 5p gain in cervical cancer reveals target over-expressed genes, including DroshaPhosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7Oncogenic role of the ubiquitin ligase subunit Skp2 in human breast cancerThe Arabidopsis mutant sleepy1gar2-1 protein promotes plant growth by increasing the affinity of the SCFSLY1 E3 ubiquitin ligase for DELLA protein substratesPhosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destructionSkp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescencePhosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKBDeregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancerRole of Cks1 overexpression in oral squamous cell carcinomas: cooperation with Skp2 in promoting p27 degradationRole of the F-box protein Skp2 in adhesion-dependent cell cycle progressionThe F-box protein SKP2 mediates androgen control of p27 stability in LNCaP human prostate cancer cells.Deregulation of p27 by oncogenic signaling and its prognostic significance in breast cancerDrugging the undruggables: exploring the ubiquitin system for drug developmentRINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesisAPC/C and retinoblastoma interaction: cross-talk of retinoblastoma protein with the ubiquitin proteasome pathwayEpstein-Barr Virus: Diseases Linked to Infection and TransformationThree different binding sites of Cks1 are required for p27-ubiquitin ligationInduction of homologue of Slimb ubiquitin ligase receptor by mitogen signalingDifferential expression of the F-box proteins Skp2 and Skp2B in breast cancerBIS targeting induces cellular senescence through the regulation of 14-3-3 zeta/STAT3/SKP2/p27 in glioblastoma cellsMutant B-RAF signaling and cyclin D1 regulate Cks1/S-phase kinase-associated protein 2-mediated degradation of p27Kip1 in human melanoma cellsThe gap junction-independent tumor-suppressing effect of connexin 43S-phase kinase-associated protein-2 (Skp2) promotes vascular smooth muscle cell proliferation and neointima formation in vivoDeregulation of F-box proteins and its consequence on cancer development, progression and metastasis.Information theoretical quantification of cooperativity in signalling complexes.Phosphorylation by mTORC1 stablizes Skp2 and regulates its oncogenic function in gastric cancerDevelopment and validation of a method for profiling post-translational modification activities using protein microarrays.Regulation of Cop9 signalosome activity by the EF-hand Ca2+-binding protein tescalcinEffects of the kava chalcone flavokawain A differ in bladder cancer cells with wild-type versus mutant p53.Chemical genetics approach to restoring p27Kip1 reveals novel compounds with antiproliferative activity in prostate cancer cellsMYC Deregulation in Primary Human Cancers.Cytoplasmic Skp2 expression is increased in human melanoma and correlated with patient survivalCharacterization of a naturally-occurring p27 mutation predisposing to multiple endocrine tumors.Polyploid giant cancer cells with budding and the expression of cyclin E, S-phase kinase-associated protein 2, stathmin associated with the grading and metastasis in serous ovarian tumor.MYC cofactors: molecular switches controlling diverse biological outcomes.
P2860
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P2860
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Skp2 is oncogenic and overexpressed in human cancers
@ast
Skp2 is oncogenic and overexpressed in human cancers
@en
type
label
Skp2 is oncogenic and overexpressed in human cancers
@ast
Skp2 is oncogenic and overexpressed in human cancers
@en
prefLabel
Skp2 is oncogenic and overexpressed in human cancers
@ast
Skp2 is oncogenic and overexpressed in human cancers
@en
P2093
P2860
P356
P1476
Skp2 is oncogenic and overexpressed in human cancers
@en
P2093
Catzavelos C
Gstaiger M
Slingerland J
P2860
P304
P356
10.1073/PNAS.081474898
P407
P577
2001-04-17T00:00:00Z