Structure of S6 kinase 1 determines whether raptor-mTOR or rictor-mTOR phosphorylates its hydrophobic motif site
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Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylationTurnover of the active fraction of IRS1 involves raptor-mTOR- and S6K1-dependent serine phosphorylation in cell culture models of tuberous sclerosismTOR Signaling in Protein Translation Regulation: Implications in Cancer Genesis and Therapeutic InterventionsStructural Basis of Human p70 Ribosomal S6 Kinase-1 Regulation by Activation Loop PhosphorylationRICTOR Amplification Defines a Novel Subset of Patients with Lung Cancer Who May Benefit from Treatment with mTORC1/2 InhibitorsRegulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networksMaintenance of metabolic homeostasis by Sestrin2 and Sestrin3Anti-remodeling effects of rapamycin in experimental heart failure: dose response and interaction with angiotensin receptor blockadeAn ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1An inhibitory role of the G-protein regulator AGS3 in mTOR-dependent macroautophagy.Current and future approaches for control of graft-versus-host disease.Cross-talk between sirtuin and mammalian target of rapamycin complex 1 (mTORC1) signaling in the regulation of S6 kinase 1 (S6K1) phosphorylation.Phosphatidic acid is a leukocyte chemoattractant that acts through S6 kinase signalingmTORC1-independent reduction of retinal protein synthesis in type 1 diabetes.The complexes of mammalian target of rapamycin.TSC1/TSC2 and Rheb have different effects on TORC1 and TORC2 activity.Genome-scale RNAi on living-cell microarrays identifies novel regulators of Drosophila melanogaster TORC1-S6K pathway signaling.The Impact of Overnutrition on Insulin Metabolic Signaling in the Heart and the KidneySerotonin increases phosphorylation of synaptic 4EBP through TOR, but eukaryotic initiation factor 4E levels do not limit somatic cap-dependent translation in aplysia neurons.Mammalian target of rapamycin (mTOR) regulates TLR3 induced cytokines in human oral keratinocytes.Cardiac insulin resistance and microRNA modulators.Mechanisms underlying acute protection from cardiac ischemia-reperfusion injuryEthyl pyruvate preserves IGF-I sensitivity toward mTOR substrates and protein synthesis in C2C12 myotubes.The mTOR (mammalian target of rapamycin) kinase maintains integrity of mTOR complex 2.Mammalian target of rapamycin inhibition in macrophages of asymptomatic HIV+ persons reverses the decrease in TLR-4-mediated TNF-α release through prolongation of MAPK pathway activation.Extended follow-up of methotrexate-free immunosuppression using sirolimus and tacrolimus in related and unrelated donor peripheral blood stem cell transplantation.Adaptive mechanisms to compensate for overnutrition-induced cardiovascular abnormalities.A unifying model for mTORC1-mediated regulation of mRNA translation.Ubiquilin-mediated Small Molecule Inhibition of Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling.TAK1 regulates autophagic cell death by suppressing the phosphorylation of p70 S6 kinase 1.Morphoproteomic confirmation of a constitutively activated mTOR pathway in high grade prostatic intraepithelial neoplasia and prostate cancer.Morphoproteomic evidence of constitutively activated and overexpressed mTOR pathway in cervical squamous carcinoma and high grade squamous intraepithelial lesions.Amino acid regulation of TOR complex 1.mTORC1 phosphorylation sites encode their sensitivity to starvation and rapamycinAutoregulation of the mechanistic target of rapamycin (mTOR) complex 2 integrity is controlled by an ATP-dependent mechanismMammalian target of rapamycin inhibition as a therapeutic strategy in the management of urologic malignanciesS6K1 alternative splicing modulates its oncogenic activity and regulates mTORC1.Mechanisms involved in the nutritional regulation of mRNA translation: features of the avian model.Current perspectives on Akt Akt-ivation and Akt-ions.Drug synergy screen and network modeling in dedifferentiated liposarcoma identifies CDK4 and IGF1R as synergistic drug targets.
P2860
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P2860
Structure of S6 kinase 1 determines whether raptor-mTOR or rictor-mTOR phosphorylates its hydrophobic motif site
description
2005 nî lūn-bûn
@nan
2005 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Structure of S6 kinase 1 deter ...... tes its hydrophobic motif site
@ast
Structure of S6 kinase 1 deter ...... tes its hydrophobic motif site
@en
Structure of S6 kinase 1 deter ...... tes its hydrophobic motif site
@nl
type
label
Structure of S6 kinase 1 deter ...... tes its hydrophobic motif site
@ast
Structure of S6 kinase 1 deter ...... tes its hydrophobic motif site
@en
Structure of S6 kinase 1 deter ...... tes its hydrophobic motif site
@nl
prefLabel
Structure of S6 kinase 1 deter ...... tes its hydrophobic motif site
@ast
Structure of S6 kinase 1 deter ...... tes its hydrophobic motif site
@en
Structure of S6 kinase 1 deter ...... tes its hydrophobic motif site
@nl
P2860
P356
P1476
Structure of S6 kinase 1 deter ...... tes its hydrophobic motif site
@en
P2093
Siraj M Ali
P2860
P304
19445-19448
P356
10.1074/JBC.C500125200
P407
P577
2005-04-04T00:00:00Z