Wnt but not BMP signaling is involved in the inhibitory action of sclerostin on BMP-stimulated bone formation
about
Control of the SOST bone enhancer by PTH using MEF2 transcription factorsDistinct modes of inhibition by sclerostin on bone morphogenetic protein and Wnt signaling pathwaysWISP-1/CCN4 regulates osteogenesis by enhancing BMP-2 activitySclerostin Inhibition in the Management of OsteoporosisFrom disease to treatment: from rare skeletal disorders to treatments for osteoporosisBiological Events in Periodontal Ligament and Alveolar Bone Associated with Application of Orthodontic ForcesFunctions of the osteocyte network in the regulation of bone massThe DAN family: modulators of TGF-β signaling and beyondControl of bone mass and remodeling by PTH receptor signaling in osteocytesCharacterization of the Structural Features and Interactions of Sclerostin: MOLECULAR INSIGHT INTO A KEY REGULATOR OF Wnt-MEDIATED BONE FORMATIONBone turnover markers in primary hyperparathyroidism.Single-dose, placebo-controlled, randomized study of AMG 785, a sclerostin monoclonal antibodyGenetic evidence that SOST inhibits WNT signaling in the limbMutational analysis of sclerostin shows importance of the flexible loop and the cystine-knot for Wnt-signaling inhibitionStructure of neuroblastoma suppressor of tumorigenicity 1 (NBL1): insights for the functional variability across bone morphogenetic protein (BMP) antagonists.Single-pulsed electromagnetic field therapy increases osteogenic differentiation through Wnt signaling pathway and sclerostin downregulation.Lrp4, a novel receptor for Dickkopf 1 and sclerostin, is expressed by osteoblasts and regulates bone growth and turnover in vivo.Sclerostin stimulates osteocyte support of osteoclast activity by a RANKL-dependent pathwayProfile of romosozumab and its potential in the management of osteoporosis.Sclerostin-erbB-3 interactions: modulation of erbB-3 activity by sclerostin.Sclerostin: current knowledge and future perspectives.Osteocyte network; a negative regulatory system for bone mass augmented by the induction of Rankl in osteoblasts and Sost in osteocytes at unloading.The transcriptional profile of mesenchymal stem cell populations in primary osteoporosis is distinct and shows overexpression of osteogenic inhibitorsCellular mechanisms of bone remodelingAnti-Sclerostin antibody inhibits internalization of Sclerostin and Sclerostin-mediated antagonism of Wnt/LRP6 signaling.Differential expression of sclerostin in adult and juvenile mouse calvariaeRole of Wnt signaling in fracture healingParathyroid hormone (PTH)-induced bone gain is blunted in SOST overexpressing and deficient miceTranscriptional Profiling of Laser Capture Microdissected Subpopulations of the Osteoblast Lineage Provides Insight Into the Early Response to Sclerostin Antibody in Rats.TIEG1-NULL OSTEOCYTES DISPLAY DEFECTS IN THEIR MORPHOLOGY, DENSITY AND SURROUNDING BONE MATRIX.Circulating sclerostin in disorders of parathyroid gland function.Prostate cancer induces bone metastasis through Wnt-induced bone morphogenetic protein-dependent and independent mechanisms.Sclerostin inhibition: a novel therapeutic approach in the treatment of osteoporosis.Plasma Sclerostin in HIV-Infected Adults on Effective Antiretroviral Therapy.Sclerostin is a locally acting regulator of late-osteoblast/preosteocyte differentiation and regulates mineralization through a MEPE-ASARM-dependent mechanism.Expression of sclerostin in the developing zebrafish (Danio rerio) brain and skeleton.Sclerostin inhibits osteoblast differentiation without affecting BMP2/SMAD1/5 or Wnt3a/β-catenin signaling but through activation of platelet-derived growth factor receptor signaling in vitroBuilding bone to reverse osteoporosis and repair fracturesA human bone morphogenetic protein antagonist is down-regulated in renal cancerOsteocytes, mechanosensing and Wnt signaling.
P2860
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P2860
Wnt but not BMP signaling is involved in the inhibitory action of sclerostin on BMP-stimulated bone formation
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Wnt but not BMP signaling is i ...... BMP-stimulated bone formation
@ast
Wnt but not BMP signaling is i ...... BMP-stimulated bone formation
@en
Wnt but not BMP signaling is i ...... BMP-stimulated bone formation
@nl
type
label
Wnt but not BMP signaling is i ...... BMP-stimulated bone formation
@ast
Wnt but not BMP signaling is i ...... BMP-stimulated bone formation
@en
Wnt but not BMP signaling is i ...... BMP-stimulated bone formation
@nl
prefLabel
Wnt but not BMP signaling is i ...... BMP-stimulated bone formation
@ast
Wnt but not BMP signaling is i ...... BMP-stimulated bone formation
@en
Wnt but not BMP signaling is i ...... BMP-stimulated bone formation
@nl
P2093
P50
P3181
P356
P1476
Wnt but not BMP signaling is i ...... BMP-stimulated bone formation
@en
P2093
Annemieke Visser
Clemens W G M Löwik
Daniël Eefting
Marcel Karperien
Paul H A Quax
Peter ten Dijke
Rutger L van Bezooijen
Socrates E Papapoulos
P3181
P356
10.1359/JBMR.061002
P407
P577
2007-01-01T00:00:00Z