about
Structure of Cdc42 in complex with the GTPase-binding domain of the 'Wiskott-Aldrich syndrome' proteinMelanoma chondroitin sulphate proteoglycan regulates cell spreading through Cdc42, Ack-1 and p130casInvolvement of alpha-PAK-interacting exchange factor in the PAK1-c-Jun NH(2)-terminal kinase 1 activation and apoptosis induced by benzo[a]pyreneSemaphorin 5A and plexin-B3 inhibit human glioma cell motility through RhoGDIalpha-mediated inactivation of Rac1 GTPaseTargeting and activation of Rac1 are mediated by the exchange factor beta-Pix.p21-activated kinase 1 phosphorylates and regulates 14-3-3 binding to GEF-H1, a microtubule-localized Rho exchange factorRhoG signals in parallel with Rac1 and Cdc42Pak1 and PIX regulate contact inhibition during epithelial wound healingBrk activates rac1 and promotes cell migration and invasion by phosphorylating paxillinGIT2 represses Crk- and Rac1-regulated cell spreading and Cdc42-mediated focal adhesion turnoverRecruitment of the Arp2/3 complex to vinculin: coupling membrane protrusion to matrix adhesionPaxillin-dependent paxillin kinase linker and p21-activated kinase localization to focal adhesions involves a multistep activation pathwayMembrane recruitment of DOCK180 by binding to PtdIns(3,4,5)P3A PAK1-PIX-PKL complex is activated by the T-cell receptor independent of Nck, Slp-76 and LAT.Vav2 activates Rac1, Cdc42, and RhoA downstream from growth factor receptors but not beta1 integrinsCoupling of PAK-interacting exchange factor PIX to GIT1 promotes focal complex disassemblyInteraction between PAK and nck: a template for Nck targets and role of PAK autophosphorylationRegulation of the p21-activated kinase (PAK) by a human Gbeta -like WD-repeat protein, hPIP1Paxillin LD4 motif binds PAK and PIX through a novel 95-kD ankyrin repeat, ARF-GAP protein: A role in cytoskeletal remodeling.Actopaxin, a new focal adhesion protein that binds paxillin LD motifs and actin and regulates cell adhesionPseudomonas aeruginosa exotoxin T induces potent cytotoxicity against a variety of murine and human cancer cell lines.Crystal structure of the Shank PDZ-ligand complex reveals a class I PDZ interaction and a novel PDZ-PDZ dimerizationA novel interaction between atrophin-interacting protein 4 and beta-p21-activated kinase-interactive exchange factor is mediated by an SH3 domainStructure and mutagenesis of the Dbl homology domainThe mechanism of PAK activation. Autophosphorylation events in both regulatory and kinase domains control activityA tyrosine-phosphorylated protein that binds to an important regulatory region on the cool family of p21-activated kinase-binding proteinsalphaPIX nucleotide exchange factor is activated by interaction with phosphatidylinositol 3-kinaseThe Shank family of postsynaptic density proteins interacts with and promotes synaptic accumulation of the beta PIX guanine nucleotide exchange factor for Rac1 and Cdc42Characterization of ARHGEF6, a guanine nucleotide exchange factor for Rho GTPases and a candidate gene for X-linked mental retardation: mutation screening in Börjeson-Forssman-Lehmann syndrome and MRX27Leukemia-associated Rho guanine nucleotide exchange factor, a Dbl family protein found mutated in leukemia, causes transformation by activation of RhoAPhosphorylation of Pak1 by the p35/Cdk5 kinase affects neuronal morphologyThe Cbl proteins are binding partners for the Cool/Pix family of p21-activated kinase-binding proteinsAndrogen receptor specifically interacts with a novel p21-activated kinase, PAK6The serine/threonine kinase PAK4 prevents caspase activation and protects cells from apoptosisBasic fibroblast growth factor stimulates activation of Rac1 through a p85 betaPIX phosphorylation-dependent pathwayThe paxillin LD motifsAkt phosphorylation of serine 21 on Pak1 modulates Nck binding and cell migrationUpregulation of p21-activated Kinase 6 in rat brain cortex after traumatic brain injuryRegulation of mitogen-activated protein kinases in cardiac myocytes through the small G protein Rac1Tiam1-IRSp53 complex formation directs specificity of rac-mediated actin cytoskeleton regulation
P2860
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P2860
description
1998 nî lūn-bûn
@nan
1998 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
name
A novel regulator of p21-activated kinases
@ast
A novel regulator of p21-activated kinases
@en
A novel regulator of p21-activated kinases
@nl
type
label
A novel regulator of p21-activated kinases
@ast
A novel regulator of p21-activated kinases
@en
A novel regulator of p21-activated kinases
@nl
prefLabel
A novel regulator of p21-activated kinases
@ast
A novel regulator of p21-activated kinases
@en
A novel regulator of p21-activated kinases
@nl
P2093
P2860
P356
P1476
A novel regulator of p21-activated kinases
@en
P2093
K A Jordon
L Van Aelst
R A Cerione
S Bagrodia
S J Taylor
P2860
P304
P356
10.1074/JBC.273.37.23633
P407
P577
1998-09-11T00:00:00Z