Identification of a selective inverse agonist for the orphan nuclear receptor estrogen-related receptor alpha
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Kaempferol is an estrogen-related receptor alpha and gamma inverse agonistCrystal structure of human estrogen-related receptor alpha in complex with a synthetic inverse agonist reveals its novel molecular mechanismCharacterization of a novel small molecule subtype specific estrogen-related receptor alpha antagonist in MCF-7 breast cancer cellsNovel drugs that target the estrogen-related receptor alpha: their therapeutic potential in breast cancerHuman fetal mesenchymal stem cells differentiate into brown and white adipocytes: a role for ERRalpha in human UCP1 expressionThe estrogen-related receptor α inverse agonist XCT 790 is a nanomolar mitochondrial uncouplerA novel steroidal inhibitor of estrogen-related receptor alpha (ERR alpha).MiR-137 targets estrogen-related receptor alpha and impairs the proliferative and migratory capacity of breast cancer cellsThe Drosophila estrogen-related receptor directs a metabolic switch that supports developmental growth.The cannabinoid receptor inverse agonist AM251 regulates the expression of the EGF receptor and its ligands via destabilization of oestrogen-related receptor α proteinEstrogen-related receptor-α is a metabolic regulator of effector T-cell activation and differentiationNuclear receptors--a perspective from Drosophila.The NR3B subgroup: an ovERRviewMolecular pathways: the metabolic regulator estrogen-related receptor α as a therapeutic target in cancer.Estrogen related receptor α (ERRα) a promising target for the therapy of adrenocortical carcinoma (ACC)Production and characterization of monoclonal antibodies to estrogen-related receptor alpha (ERRα) and use in immunoaffinity chromatographyMCF-7aro/ERE, a novel cell line for rapid screening of aromatase inhibitors, ERalpha ligands and ERRalpha ligandsInverse agonist of estrogen-related receptor α suppresses the growth of triple negative breast cancer cells through ROS generation and interaction with multiple cell signaling pathwaysEstrogen-related receptor alpha is critical for the growth of estrogen receptor-negative breast cancer.ERRalpha: a metabolic function for the oldest orphan.Development of a stable cell line with an intact PGC-1α/ERRα axis for screening environmental chemicals.Orphan nuclear receptor oestrogen-related receptor γ (ERRγ) plays a key role in hepatic cannabinoid receptor type 1-mediated induction of CYP7A1 gene expression.Estrogen related receptor alpha in castration-resistant prostate cancer cells promotes tumor progression in boneThiadiazole-a promising structure in medicinal chemistry.Mechanism of cardiomyocyte PGC-1α gene regulation by ERRα.Mitochondrial biogenesis is required for the anchorage-independent survival and propagation of stem-like cancer cellsExercise-induced changes in tumour LDH-B and MCT1 expression are modulated by oestrogen-related receptor alpha in breast cancer-bearing BALB/c mice.Estrogen-related receptor alpha is a repressor of phosphoenolpyruvate carboxykinase gene transcription.Modulation of estrogen related receptor alpha activity by the kinesin KIF17.MYC-dependent oxidative metabolism regulates osteoclastogenesis via nuclear receptor ERRαPeroxisome proliferator-activated receptor-gamma coactivator-1alpha controls transcription of the Sirt3 gene, an essential component of the thermogenic brown adipocyte phenotype.Kinase suppressor of ras 1 (KSR1) regulates PGC1α and estrogen-related receptor α to promote oncogenic Ras-dependent anchorage-independent growthSynthetic FXR agonist GW4064 is a modulator of multiple G protein-coupled receptorsOn the intractability of estrogen-related receptor alpha as a target for activation by small molecules.Identification of seven genes essential for male fertility through a genome-wide association study of non-obstructive azoospermia and RNA interference-mediated large-scale functional screening in Drosophila.Identification of Estrogen-Related Receptor α Agonists in the Tox21 Compound Library.Modulation of Autophagy by a Small Molecule Inverse Agonist of ERRα Is Neuroprotective.Identification of Estrogen Receptor α Antagonists from Natural Products via In Vitro and In Silico Approaches.Cholesterol as an Endogenous ERRα Agonist: A New Perspective to Cancer Treatment
P2860
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P2860
Identification of a selective inverse agonist for the orphan nuclear receptor estrogen-related receptor alpha
description
2004 nî lūn-bûn
@nan
2004 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Identification of a selective ...... strogen-related receptor alpha
@ast
Identification of a selective ...... strogen-related receptor alpha
@en
Identification of a selective ...... strogen-related receptor alpha
@nl
type
label
Identification of a selective ...... strogen-related receptor alpha
@ast
Identification of a selective ...... strogen-related receptor alpha
@en
Identification of a selective ...... strogen-related receptor alpha
@nl
prefLabel
Identification of a selective ...... strogen-related receptor alpha
@ast
Identification of a selective ...... strogen-related receptor alpha
@en
Identification of a selective ...... strogen-related receptor alpha
@nl
P2093
P356
P1476
Identification of a selective ...... strogen-related receptor alpha
@en
P2093
Brett B Busch
Douglas W Sapp
Peter Ordentlich
Raju Mohan
Richard Martin
Robert A Horlick
Sihong Zhou
William C Stevens
P304
P356
10.1021/JM049334F
P407
P577
2004-11-04T00:00:00Z