Mitochondrial biogenesis is required for the anchorage-independent survival and propagation of stem-like cancer cells
about
Cancer stem cell metabolismOn metabolic reprogramming and tumor biology: A comprehensive survey of metabolism in breast cancerNADH autofluorescence, a new metabolic biomarker for cancer stem cells: Identification of Vitamin C and CAPE as natural products targeting "stemness".Mitochondrial mass, a new metabolic biomarker for stem-like cancer cells: Understanding WNT/FGF-driven anabolic signaling.Extracellular pH Modulates Neuroendocrine Prostate Cancer Cell Metabolism and Susceptibility to the Mitochondrial Inhibitor Niclosamide.Dissecting tumor metabolic heterogeneity: Telomerase and large cell size metabolically define a sub-population of stem-like, mitochondrial-rich, cancer cellsMetabolic Reprogramming and Dependencies Associated with Epithelial Cancer Stem Cells Independent of the Epithelial-Mesenchymal Transition Program.Bedaquiline, an FDA-approved antibiotic, inhibits mitochondrial function and potently blocks the proliferative expansion of stem-like cancer cells (CSCs).Repurposing atovaquone: targeting mitochondrial complex III and OXPHOS to eradicate cancer stem cells.Germline BRCA1 mutation reprograms breast epithelial cell metabolism towards mitochondrial-dependent biosynthesis: evidence for metformin-based "starvation" strategies in BRCA1 carriers.Doxycycline is an NF-κB inhibitor that induces apoptotic cell death in malignant T-cells.TRIM28 multi-domain protein regulates cancer stem cell population in breast tumor development.Loss of fructose-1,6-bisphosphatase induces glycolysis and promotes apoptosis resistance of cancer stem-like cells: an important role in hexavalent chromium-induced carcinogenesis.Mitochondrial "power" drives tamoxifen resistance: NQO1 and GCLC are new therapeutic targets in breast cancer.Inhibition of stress-inducible HSP70 impairs mitochondrial proteostasis and function.Hallmarks of cancer stem cell metabolism.Mitochondrial dynamics as regulators of cancer biology.The master role of microphthalmia-associated transcription factor in melanocyte and melanoma biology.Targeting hypoxic cancer stem cells (CSCs) with Doxycycline: Implications for optimizing anti-angiogenic therapy.A Transcript-Specific eIF3 Complex Mediates Global Translational Control of Energy Metabolism.Mitochondrial biomarkers predict tumor progression and poor overall survival in gastric cancers: Companion diagnostics for personalized medicine.Vitamin C and Doxycycline: A synthetic lethal combination therapy targeting metabolic flexibility in cancer stem cells (CSCs).Mitochondrial markers predict recurrence, metastasis and tamoxifen-resistance in breast cancer patients: Early detection of treatment failure with companion diagnostics.Mitochondrial mRNA transcripts predict overall survival, tumor recurrence and progression in serous ovarian cancer: Companion diagnostics for cancer therapy.Mitoriboscins: Mitochondrial-based therapeutics targeting cancer stem cells (CSCs), bacteria and pathogenic yeast.Targeting cancer stem cell propagation with palbociclib, a CDK4/6 inhibitor: Telomerase drives tumor cell heterogeneity.Therapeutic potential of the metabolic modulator phenformin in targeting the stem cell compartment in melanoma.Doxycycline: new tricks for an old drug.Transcriptomic analysis of mitochondrial TFAM depletion changing cell morphology and proliferation.Targeting flavin-containing enzymes eliminates cancer stem cells (CSCs), by inhibiting mitochondrial respiration: Vitamin B2 (Riboflavin) in cancer therapy.Doxycycline induces apoptosis via ER stress selectively to cells with a cancer stem cell-like properties: importance of stem cell plasticity.Proteomic analysis of mitochondria: biological and clinical progresses in cancer.PGC1α: Friend or Foe in Cancer?Hypoxic regulation of the expression of genes encoded estrogen related proteins in U87 glioma cells: eff ect of IRE1 inhibition.Metabolic regulation of glioma stem-like cells in the tumor micro-environment.Regulated Cell Death of Lymphoma Cells after Graded Mitochondrial Damage is Differentially Affected by Drugs Targeting Cell Stress Responses.Exploiting mitochondrial targeting signal(s), TPP and bis-TPP, for eradicating cancer stem cells (CSCs).YAP1-TEAD1 signaling controls angiogenesis and mitochondrial biogenesis through PGC1α.Targeting Tumor Metabolism: A New Challenge to Improve Immunotherapy.Elucidating the Metabolic Plasticity of Cancer: Mitochondrial Reprogramming and Hybrid Metabolic States.
P2860
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P2860
Mitochondrial biogenesis is required for the anchorage-independent survival and propagation of stem-like cancer cells
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
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2015年學術文章
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name
Mitochondrial biogenesis is re ...... tion of stem-like cancer cells
@en
type
label
Mitochondrial biogenesis is re ...... tion of stem-like cancer cells
@en
prefLabel
Mitochondrial biogenesis is re ...... tion of stem-like cancer cells
@en
P2093
P2860
P356
P1433
P1476
Mitochondrial biogenesis is re ...... tion of stem-like cancer cells
@en
P2093
Anna Rita Cappello
Arianna De Luca
Bela Ozsvari
Duncan L Smith
Marco Fiorillo
Maria Peiris-Pagès
Rosa Sanchez-Alvarez
Ubaldo E Martinez-Outschoorn
Vincenzo Pezzi
P2860
P304
14777-14795
P356
10.18632/ONCOTARGET.4401
P407
P577
2015-06-01T00:00:00Z