On the mechanism of interaction of potent surmountable and insurmountable antagonists with the prostaglandin D2 receptor CRTH2

On the mechanism of interaction of potent surmountable and insurmountable antagonists with the prostaglandin D2 receptor CRTH2

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http://www.wikidata.org/entity/Q28292274
The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptorsProstanoid receptor antagonists: development strategies and therapeutic applicationsFevipiprant (QAW039), a Slowly Dissociating CRTh2 Antagonist with the Potential for Improved Clinical Efficacy.Antagonism of the prostaglandin D2 receptor CRTH2 attenuates asthma pathology in mouse eosinophilic airway inflammation.DP(2) receptor antagonists in development.Novel CRTH2 antagonists: a review of patents from 2006 to 2009.Approaches for probing allosteric interactions at 7 transmembrane spanning receptors.Biochemical and pharmacological characterization of AZD1981, an orally available selective DP2 antagonist in clinical development for asthma.The C-terminal tail of CRTH2 is a key molecular determinant that constrains Galphai and downstream signaling cascade activation.Applying label-free dynamic mass redistribution technology to frame signaling of G protein-coupled receptors noninvasively in living cells.
P2860

On the mechanism of interaction of potent surmountable and insurmountable antagonists with the prostaglandin D2 receptor CRTH2

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http://www.wikidata.org/entity/Q28292274
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2006 nî lūn-bûn
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2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2006 թվականի ապրիլին հրատարակված գիտական հոդված
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2006年の論文
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2006年学术文章
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On the mechanism of interactio ...... rostaglandin D2 receptor CRTH2
@ast
On the mechanism of interactio ...... rostaglandin D2 receptor CRTH2
@en
On the mechanism of interactio ...... rostaglandin D2 receptor CRTH2
@nl
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label
On the mechanism of interactio ...... rostaglandin D2 receptor CRTH2
@ast
On the mechanism of interactio ...... rostaglandin D2 receptor CRTH2
@en
On the mechanism of interactio ...... rostaglandin D2 receptor CRTH2
@nl
prefLabel
On the mechanism of interactio ...... rostaglandin D2 receptor CRTH2
@ast
On the mechanism of interactio ...... rostaglandin D2 receptor CRTH2
@en
On the mechanism of interactio ...... rostaglandin D2 receptor CRTH2
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P356
P1433
P1476
On the mechanism of interactio ...... rostaglandin D2 receptor CRTH2
@en
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698