The intracellular cytoplasmic domain of the Alzheimer's disease amyloid precursor protein interacts with phosphotyrosine-binding domain proteins in the yeast two-hybrid system
about
VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasisAutoinhibition of X11/Mint scaffold proteins revealed by the closed conformation of the PDZ tandemA pilot proteomic study of amyloid precursor interactors in Alzheimer's diseaseSequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domainReduced hippocampal insulin-degrading enzyme in late-onset Alzheimer's disease is associated with the apolipoprotein E-epsilon4 alleleDeletion of Mint proteins decreases amyloid production in transgenic mouse models of Alzheimer's diseaseA role for Mints in transmitter release: Mint 1 knockout mice exhibit impaired GABAergic synaptic transmissionStructure of the C-terminal phosphotyrosine interaction domain of Fe65L1 complexed with the cytoplasmic tail of amyloid precursor protein reveals a novel peptide binding modeAutoinhibition of Mint1 adaptor protein regulates amyloid precursor protein binding and processingThe beta-amyloid precursor protein functions as a cytosolic anchoring site that prevents Fe65 nuclear translocationThe neuronal adaptor protein X11alpha interacts with the copper chaperone for SOD1 and regulates SOD1 activityMint2/X11-like colocalizes with the Alzheimer's disease amyloid precursor protein and is associated with neuritic plaques in Alzheimer's diseaseFe65, a ligand of the Alzheimer's beta-amyloid precursor protein, blocks cell cycle progression by down-regulating thymidylate synthase expressionThe beta-amyloid precursor protein APP is tyrosine-phosphorylated in cells expressing a constitutively active form of the Abl protoncogeneSynergistic effects of Munc18a and X11 proteins on amyloid precursor protein metabolismProteolytic processing of Alzheimer's β-amyloid precursor proteinFe65 and the protein network centered around the cytosolic domain of the Alzheimer's beta-amyloid precursor proteinDexras1 interacts with FE65 to regulate FE65-amyloid precursor protein-dependent transcriptionFE65 interacts with ADP-ribosylation factor 6 to promote neurite outgrowthInsulin-degrading enzyme rapidly removes the beta-amyloid precursor protein intracellular domain (AICD)FE65 as a link between VLDLR and APP to regulate their trafficking and processingInteraction of Mint2 with TrkA is involved in regulation of nerve growth factor-induced neurite outgrowthMint3/X11gamma is an ADP-ribosylation factor-dependent adaptor that regulates the traffic of the Alzheimer's Precursor protein from the trans-Golgi network.Loss of c-Jun N-terminal kinase-interacting protein-1 does not affect axonal transport of the amyloid precursor protein or Aβ production.Direct visualization of the gamma secretase-generated carboxyl-terminal domain of the amyloid precursor protein: association with Fe65 and translocation to the nucleus.Rab6 interacts with the mint3 adaptor protein.Screening for PTB domain binding partners and ligand specificity using proteome-derived NPXY peptide arrays.Role of X11 and ubiquilin as in vivo regulators of the amyloid precursor protein in DrosophilaThe disabled 1 phosphotyrosine-binding domain binds to the internalization signals of transmembrane glycoproteins and to phospholipidsIdentification and characterization of a neuronal enriched novel transcript encoding the previously described p60Fe65 isoform.Calsyntenin-1 mediates axonal transport of the amyloid precursor protein and regulates Aβ productionAmyloid-beta protein precursor (AbetaPP) intracellular domain-associated protein-1 proteins bind to AbetaPP and modulate its processing in an isoform-specific manner.Modulation of gene expression and cytoskeletal dynamics by the amyloid precursor protein intracellular domain (AICD)FE65 in Alzheimer's disease: neuronal distribution and association with neurofibrillary tanglesAmyloid Precursor Protein (APP) Metabolites APP Intracellular Fragment (AICD), Aβ42, and Tau in Nuclear Roles.Interaction of ASK1 and the beta-amyloid precursor protein in a stress-signaling complex.Genome-wide SNP typing reveals signatures of population history.Single-Cell Detection of Secreted Aβ and sAPPα from Human IPSC-Derived Neurons and Astrocytes.The role of presenilin and its interacting proteins in the biogenesis of Alzheimer's beta amyloidSpecific intercellular binding of the beta-amyloid precursor protein to the presenilins induces intercellular signaling: its significance for Alzheimer's disease.
P2860
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P2860
The intracellular cytoplasmic domain of the Alzheimer's disease amyloid precursor protein interacts with phosphotyrosine-binding domain proteins in the yeast two-hybrid system
description
1996 nî lūn-bûn
@nan
1996 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
The intracellular cytoplasmic ...... in the yeast two-hybrid system
@ast
The intracellular cytoplasmic ...... in the yeast two-hybrid system
@en
The intracellular cytoplasmic ...... in the yeast two-hybrid system
@nl
type
label
The intracellular cytoplasmic ...... in the yeast two-hybrid system
@ast
The intracellular cytoplasmic ...... in the yeast two-hybrid system
@en
The intracellular cytoplasmic ...... in the yeast two-hybrid system
@nl
prefLabel
The intracellular cytoplasmic ...... in the yeast two-hybrid system
@ast
The intracellular cytoplasmic ...... in the yeast two-hybrid system
@en
The intracellular cytoplasmic ...... in the yeast two-hybrid system
@nl
P2860
P1433
P1476
The intracellular cytoplasmic ...... in the yeast two-hybrid system
@en
P2093
C C Miller
D M McLoughlin
P2860
P304
P356
10.1016/S0014-5793(96)01128-3
P407
P577
1996-11-18T00:00:00Z